ABM Cell Lines

Tumor cells

Thawing Protocol

Cell Line Catalog (Volume 2)

T8263 CWR-R1 Cells

T8263 CWR-R1 Cells are a human recurrent prostate carcinoma co-culture (epithelial + stromal fibroblasts) with AR-H874Y mutation enabling low-androgen activation. Derived from the CWR22 xenograft; supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8272 sNF94.3 Cells

T8272 sNF94.3 Cells are a human Schwann cell-like NF1 tumor cell line expressing S100, p75, and neurofibromin, with high histological resemblance to plexiform neurofibromas. Derived from a 43-year-old female. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8273 DB-1 Cells

T8273 DB-1 Cells are human melanoma cells expressing NGF, Iba1, TREM2, CD11b, CD68, and SV40 (RT-PCR). Polygonal morphology, 40,000 cells/cm&sup2; seeding, ~48 hr doubling. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8286 CDS11 Cells

T8286 CDS11 Cells are stem cell-related, invasive human secondary chondrosarcoma cells (Ollier disease-associated) with IDH1 p.R132L, TP53 p.P72R mutations and CDKN2A deletion. Suitable for subcutaneous and orthopedic animal models. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8287 T-CDS17 Cells

T8287 by Applied Biological Materials (ABM) is T-CDS17, a human dedifferentiated chondrosarcoma line with IDH2 p.R172G, TP53 mutations (p.P72R, p.S215R), and MDM2 amplification. Stem-cell-related and invasive; proliferates in subcutaneous and orthopedic mouse models. ECM coating required; culture in PriGrow III + 10% FBS + GlutaMAX + Pen/Strep at 37.0&deg;C.

T8288 T-CDS17-4 Cells

T8288 T-CDS17-4 Cells are stem cell-related, invasive human dedifferentiated chondrosarcoma cells with TP53 mutations and MDM2 amplification, suitable for subcutaneous and orthopedic animal models. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8289 UWO23 (HPV33) Cells

T8289 UWO23 (HPV33) Cells are HPV33-expressing human oral tongue cancer cells from a 53-year-old male donor, used to study HPV-driven HNSCC biology. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8290 UWO37 (HPV16) Cells

UWO37 (HPV16) Cells (T8290) by MBP are derived from oral tongue cancer and express HPV16. Model for investigating HPV and head and neck squamous cell carcinoma. Split ratio 1:2–1:3, PDT 37–45h. BSL II. 1&times;106 cells / 1.0 mL, frozen. MTA required.

T8292 HN12 Cells

T8292 HN12 Cells are human metastatic HNSCC cells expressing truncated p53 protein, used for apoptosis and therapeutic pathway research in head and neck squamous cell carcinoma. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.

T8293 U2OS Cells

T8293 by Applied Biological Materials (ABM) is a CRISPR/Cas9 HMGN1-knockout U2OS osteosarcoma line. The parental U2OS carries wild-type p53, wild-type Rb, and is p16-negative (CDKN2A-null) &mdash; a well-characterized CDK pathway background. Suited for chromatin biology, DNA damage, CDK4/6 inhibitor, and osteosarcoma drug-screening applications.

T8319 MELA15 Cells

T8319 by Applied Biological Materials (ABM) is MELA15, a human melanoma cell line from an inguinal lymph node metastasis of a 39-year-old Caucasian female. BRAF wild-type with confirmed NRAS Q61R (61 CAA&rarr;CGA) and PI3KCA wild-type &mdash; an NRAS-mutant profile relevant for MEK inhibitor studies and BRAF-wt negative controls in drug screening panels. Population doubling time is ~30 hours.

T8320 BCJ-4T Cells

T8320 BCJ-4T Cells are human bladder urothelial (transitional cell) carcinoma cells expressing amelogenin as a potential biomarker, with ~29.2 hr doubling time. Supplied by ABM as 1&times;106 cells/1.0 ml, frozen; BSL-2; RUO. MTA required.