Excel Scientific Sealing Films

<h2 dir="ltr">What are light-sensitive sealing films?</h2>
 Light-sensitive sealing films are light-blocking microplate seals &mdash; typically aluminum foil or opaque pigmented polymer &mdash; used to protect photosensitive contents from light exposure during incubation, detection, and storage. They prevent the photobleaching of fluorophores and the photodegradation of light-labile reagents and drugs, while still stopping evaporation and well-to-well contamination. Foil versions also block gases and tolerate &minus;80 &deg;C storage, and several are pierceable for robotic access. Buy from this category whenever a sample's signal or stability depends on keeping light out of the wells.
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<h2 dir="ltr">What you will find: </h2>
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Black opaque sealing films for full light protection
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Semi-opaque light-reducing films for controlled exposure workflows
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Standard formats for 96-well microplates (approx. 127 &times; 80 mm)
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384-well compatible sealing films for high-throughput assays
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Adhesive sealing films for secure microplate closure
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Optical-compatible films for fluorescence-based assays
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Pierceable and non-pierceable film options for workflow flexibility
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High-barrier films for evaporation and contamination control
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<h2 dir="ltr"> How to choose light-sensitive films</h2>
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Confirm full light-blocking Choose fully opaque foil or pigmented film, not tinted clear film, when contents are strongly photosensitive; foil blocks light completely, while pigmented polymer films balance light protection with easier handling.
Decide whether you still need optical access Light-sensitive films are not for reading through; if a protocol requires both light protection and optical detection, seal for storage with an opaque film and switch to an optical film at the read step.
Check temperature and storage rating Foil light-blocking films often double as cold storage seals rated to &minus;80 &deg;C, suiting light-sensitive compound libraries; confirm the stated range before archiving frozen samples.
<h2 dir="ltr"> Compare light-sensitive film variants.</h2>
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<li data-section-id="17gvbe2" data-start="0" data-end="165">Opaque aluminum foil: Provides maximum light blocking and supports &minus;80 &deg;C storage; compatible with storage and polypropylene plates, as well as robotic probes.</li>
<li data-section-id="1jnkzrj" data-start="167" data-end="335">Pierceable foil: For photosensitive high-throughput screening (HTS) and automated sample access; compatible with polypropylene plates and liquid handling systems.</li>
<li data-section-id="1o0gauf" data-start="337" data-end="479" data-is-last-node="">Black/amber polymer film: For light-sensitive applications requiring easier benchtop handling; compatible with assay and culture plates.</li>
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<h2 dir="ltr"> Specifications context</h2>
 Light-sensitive films are characterized by opacity, temperature range, and whether they are pierceable. Aluminum foil offers complete light blocking plus a gas and moisture barrier, and often carries a &minus;80 &deg;C to +110 &deg;C rating for combined light protection and freezer storage. Pigmented polymer films are easier to handle for benchtop work. Because a conformable foil presses down into each well, it leaves a defined impression around every well that lets the user confirm a complete seal by eye, and the opaque, intact layer doubles as a tamper-evident and contamination barrier while plates move between the bench, incubator, and freezer. Because these films are not optically clear, they are removed before any fluorescence or absorbance read. As of 2026, they ship in packs of 100 or rolls in a low-to-mid price tier.&nbsp; 
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Instead of struggling with inconsistent results, choose a sealing solution designed specifically for light-sensitive work. <a href="https://mbpinc.net/contact-us">Connect with the MBP team</a> to find the right film format, compatibility, and bulk supply option for your application.

Light Sensitive Film

FoilSeal™, PCR

FoilSeal features a specially formulated adhesive that provides an excellent seal to minimize evaporation, reduce cross-contamination and prevent spillage.

Application

Temperature Range

Manufacturer

FoilSeal™, PCR, light sensitive assays and robotics, -20°C to +120°C, 100 Sealing Films/Pack

FoilSeal™, PCR, Sterile, light sensitive assays and robotics, -20°C to +120°C, 50 Sealing Films/Pack

PCR & qPCR Film

SealPlate® ColorTab™

Each end-tab features a colored dot and white writing area.

SealPlate® ColorTab™, Assorted, 50/Cs

SealPlate® ColorTab™, Blue, 100/Cs

SealPlate® ColorTab™, Green, 100/Cs

SealPlate® ColorTab™, Lavender, 100/Cs

SealPlate® ColorTab™, Orange, 100/Cs

SealPlate® ColorTab™, Red, 100/Cs

SealPlate® MiniStrips™, 4 Strips per Sheet, 2X8 Rows per Strip, Sterile

SealPlate® RollMate™, Dispenser +1 Roll of SealPlate Film, 500 Pre-Scored Sheets

Pre-scored film on a roll is a more economical and efficient alternative to rapidly seal microplates or racked test tubes; faster than applying single sheeted film.

<h2 dir="ltr">What are cell and tissue culture sealing films?</h2>
 Cell and tissue culture sealing films are breathable, gas-permeable membranes applied to multiwell culture plates to maintain sterility and limit evaporation while letting oxygen and carbon dioxide pass through to the cells. Unlike airtight polyester or foil seals, the porous membrane supports aerobic respiration, so cultures stay viable through multi-day incubations, shaking, and even plate inversion. They use a medical-grade, non-cytotoxic adhesive and suit polystyrene and polypropylene culture plates. Buy from this category for live-cell, tissue, and microbial culture, where gas exchange and sterility matter more than an airtight seal.
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Gas-permeable sealing films for optimal cell growth conditions
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Adhesive sealing films for microplates and culture plates
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Optical clear films for microscopy and imaging applications
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Pierceable films for repeated sample access
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Sterile sealing films for contamination-sensitive workflows
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Heat-resistant films for incubation and thermal applications
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<h2 dir="ltr"> How to choose cell and tissue culture films</h2>
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Confirm gas permeability Choose a hydrophobic, gas-permeable membrane with a defined pore size &mdash; commonly around 10&ndash;50 &micro;m &mdash; so O₂ and CO₂ exchange freely while liquid and contaminants stay out.
Verify the adhesive is non-cytotoxic For live cells, select a medical-grade, non-cytotoxic adhesive; the standard pressure-sensitive adhesives used on storage films are not validated for cell contact.
Match the plate and culture format Confirm the film fits 96-, 384-, or deep-well culture plates and supports shaking or inversion if your protocol requires it; deep-well cultures place more demand on the seal.
Decide on sterility and imaging Choose sterile film for cell work; if you image during incubation, select a film with optically clear windows so plates can be read without unsealing.
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<h2 dir="ltr">Specifications context</h2>
 Culture films are defined by gas permeability, pore size, adhesive biocompatibility, and sterility. A porous membrane with 10&ndash;50 &micro;m pores and high moisture-vapor transmission supports aerobic metabolism while limiting evaporation. A medical-grade, non-cytotoxic adhesive keeps cells viable, and sterile packaging prevents contamination of primary cultures. Some plate-reader manufacturers recommend a breathable moisture-barrier seal to prevent moisture release into the instrument. Because the membrane is gas-permeable rather than airtight, a breathable culture film is removed and replaced with an airtight foil or polyester seal before any subsequent freezing or chemical-processing step, where evaporation control and a full barrier &mdash; not gas exchange &mdash; becomes the priority. These films ship sterile in packs of 100 in a mid-price tier.&nbsp; 
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For product details, compatibility guidance, or bulk requirements, <a href="https://mbpinc.net/contact-us">the MBP team </a>can help you select the right sealing film for your specific culture system.

Cell & Tissue Culture Film

Product Literature

SealPlate® SealMate™ Starter Kit

For fast and efficient microplate sealing, The SealMate SealPlate Starter Kit features a re-usable dispenser and two rolls of perforated film.

SealPlate® SealMate™ Starter Kit, SealMate Dispenser + 2 Rolls of SealPlate® Film, 100 Sheets/Roll

SealPlate® SealMate™ Starter Kit, SealMate Dispenser + 2 Rolls of SealPlate® Film, 100 Sheets/Roll, Sterile

SealPlate® for General laboratory use

SealPlate minimizes evaporation, prevents well-to-well contamination and spillage. Eliminates the “edge effect” which can occur with plate lids (e.g. greater evaporation in the outside plate wells).

SealPlate®, General laboratory use, short-term storage, incubation and ELISA, -40°C to +120°C, 100 Sealing Films/Pack

SealPlate®, Sterile, General laboratory use, short-term storage, incubation and ELISA,Temperature Range: -40°C to +120°C, 100 Sealing Films/Pack

<h2 dir="ltr">What are PCR and qPCR sealing films?</h2>
 PCR and qPCR sealing films are optically clear microplate seals applied to 96- and 384-well PCR plates to create an airtight barrier through every thermal cycle, preventing evaporation, condensation, and cross-well contamination while still letting fluorescence pass through to the qPCR detector. Most are pressure-sensitive adhesive (PSA) or heat-activated films built on polypropylene or polyester (PET) with low-autofluorescence chemistry. Standard formats fit SBS sheets of approximately 137 &times; 80 mm. Buy from this category whenever the seal sits on a plate that will be thermally cycled or read in real time, not stored or incubated under simple lids. 
<h2 dir="ltr">What you will find:</h2>
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<li dir="ltr" role="presentation">Optical-grade qPCR sealing films for fluorescence-based detection</li>
<li dir="ltr" role="presentation">Standard adhesive PCR films for routine thermal cycling</li>
<li dir="ltr" role="presentation">96-well microplate sealing films for standard PCR workflows</li>
<li dir="ltr" role="presentation">384-well compatible sealing films for high-throughput assays</li>
<li dir="ltr" role="presentation">High-temperature resistant films for -40&deg;C to 120&deg;C cycling</li>
<li dir="ltr" role="presentation">Low-evaporation sealing films for reaction stability</li>
<li dir="ltr" role="presentation">DNase/RNase-free films for contamination-sensitive assays</li>
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<h2 dir="ltr">How to choose PCR or qPCR sealing film</h2>
 Confirm true optical clarity if you read fluorescence Not every "clear" sealing film has enough optical clarity and low enough autofluorescence for real-time PCR; choose a film specifically rated for qPCR with high light transmittance and no autofluorescence so excitation and emission pass cleanly. Standard storage films can suppress the signal. Decide between adhesive (PSA) and heat-seal Pressure-sensitive adhesive films are applied with a roller or paddle at the bench and peel off; heat-seal films bond under a plate sealer at controlled temperature and pressure for the strongest barrier in high-throughput and automated qPCR. PSA suits flexible workflows; heat-seal suits volume. Match the plate, thermal cycler, and skirt Confirm the film fits 96- or 384-well plates from your supplier and seats properly under the heated lid of your thermal cycler &mdash; full-skirt, semi-skirt, and non-skirt plates have different sealing surfaces. Sheet size near 137 &times; 80 mm is the SBS norm. Check chemical and temperature resistance PCR plate sealers and thermal cyclers reach 105 &deg;C routinely, and some films are rated to 150 &deg;C; check that the film and adhesive withstand the cycler protocol and the master mix without softening, lifting at corners, or leaving residue after peeling.
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<h2 dir="ltr">Specifications context</h2>
 Quality qPCR films are defined by light transmittance (typically &ge; 90 %), absence of autofluorescence, evaporation rate (commonly &le; 3 %), thermal tolerance to about 105 &deg;C with high-temperature variants to 150 &deg;C, and a DNase/RNase- and human-DNA-free certification appropriate for amplification. Most are supplied as flat SBS-format sheets around 137 &times; 80 mm, packed 100 per box; some have perforated end tabs for one-handed peeling. As of 2026, they sit in a low-to-mid price tier, with heat-seal films at the higher end.&nbsp; 
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<a href="https://mbpinc.net/contact-us">Connect with the MBP team today</a>&nbsp;to find the perfect optical or standard seal for your amplification workflow. Browse the wider&nbsp;<a href="https://mbpinc.net/consumables/sealing-films">sealing films range </a>for post-PCR archiving and reorder today via <a href="https://mbpinc.net/quickorder">Quick Order</a>.

DataSheet

ThermalSeal RTS Optically Clear, Silicone Adhesive

Are You Using 4311971 MicroAmp Optical Adhesive Film by Thermofisher? Try a direct alternative from the MBP team that matches the performance, clarity, and sealing reliability - at a more competitive price. You can press the "Email For Quote" button above to get started.

Optical Adhesive Films For PCR, Storage & Crystallization - Replaces 4311971 by Thermofisher 100 Seals/Case

ThermalSeal RTS™, Optically Clear, Silicone Adhesive, 25 Sealing Films/Pack

ThermalSeal RTS™, Optically Clear, Silicone Adhesive, Sterile, qPCR, long-term storage, protein crystallography & HPLC, -80°C to +105°C, 50 Sealing Films/Pack

ThermalSeal® 2™ and ThermalSeal® A™

ThermalSeal 2 and ThermalSeal A feature a soft, extra thick, conformable adhesive that forms a very strong seal around raised wells to minimize evaporation and cross-contamination.

ThermalSeal2™, PCR, -40°C to +120°Cl, 100 Sealing Films/Pack, 100 Sealing Films/Pack

ThermalSeal® Advanced, PCR, -40°C to +120°C, 100 Sealing Films/Pack

ThermalSeal® RT2 for Optically Clear for Flat-Top Plates

Are you using the MSB1001 Microseal by Biorad? Try a direct alternative from the MBP team that matches the performance, clarity, and sealing reliability - at a more competitive price. You can press the "Email For Quote" button above to get started.

ThermalSeal RT2™, Optically Clear for Flat-Top Plates, qPCR, -40°C to +120°C, 100 Sealing Films/Pack

ThermalSeal RT2RR™, Optically Clear for Raised Rim Plates, qPCR, -40°C to +120°C, 100 Sealing Films/Pack

ThermalSeal®, PCR and general storage

ThermalSeal features a moderate strength adhesive for ease of removal.