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Purification System Accessories: Cartridges and Collectors

Automated purification system accessories include tip combs, magnetic tip combs, deep-well plates, elution plates, reagent vessels, sample racks, and control devices used with automated nucleic acid purification platforms. These components support sample processing, reagent handling, and magnetic bead-based purification workflows and should be matched to the appropriate instrument model.

MBP provides purchase order procurement and direct support for automated purification system accessories for US and Canadian research, clinical, and biotechnology laboratories. Request a quote for IsoPure™ accessories, consumables, and replacement components by contacting customerservice@mbpinc.net.

Automated Purification System Accessories

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AP1016-6W

6-well reagent vessel for IsoPure Mini, cs 100

List Price:

USD183.10

Online Price:

USD130.79

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AP1016-MC

8-place magnetic tip comb for IsoPure Mini, cs 50

List Price:

USD102.62

Online Price:

USD73.30

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AP1096-DWP

96 deep well plates for IsoPure™, cs 50

List Price:

USD365.01

Online Price:

USD260.72

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AP1096-ELP

96 well elution plates for IsoPure™, cs 100

List Price:

USD695.26

Online Price:

USD496.61

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AP1016-ASR

Aluminum Sample Rack for AP1016-6W reagent vessels

List Price:

USD701.50

Online Price:

USD501.07

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AP1016-DC

IsoPURE Mini Demo Case

List Price:

USD708.82

Online Price:

USD506.30

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AP1024-DWP

IsoPURE™ 24 14.6mL Deep Well Plate, 24/pack

List Price:

USD319.99

Online Price:

USD228.57

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AP1024-TC

IsoPURE™ 24 Tip Combs, 24/pack

List Price:

USD306.21

Online Price:

USD218.72

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AP1096-TC

Tip Comb for IsoPure™ 96, cs 50

List Price:

USD365.01

Online Price:

USD260.72

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AP1016-TAB

Android tablet preloaded with IsoPure™ Mini app

List Price:

USD368.54

Online Price:

USD263.24

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Showing 1 to 10 of 10 results

What Are Automated Purification System Accessories?

Automated purification system accessories include consumables and support components used with automated nucleic acid purification platforms. Common accessories include tip combs, magnetic tip combs, deep-well plates, elution plates, reagent vessels, sample racks, and system control devices. These components support sample preparation, reagent handling, magnetic bead-based purification workflows, and routine instrument operation. Choose Automated Purification System Accessories to support efficient magnetic bead-based purification, minimize workflow interruptions, and maintain reproducible results.

What You Will Find:

Tip combs and magnetic tip combs for automated magnetic bead-based nucleic acid purification workflows.
Deep-well and elution plates designed for sample processing, washing, and nucleic acid recovery.
Reagent vessels for automated handling of buffers, wash solutions, and purification reagents.
Sample racks and support components for organized workflow setup and consumable positioning.
Platform-specific accessories and control devices that support routine operation of IsoPure™ purification systems.

How to Choose Accessories for Automated Purification Systems

Tip combs and magnetic tip combs

Tip combs and magnetic tip combs are used during automated magnetic bead handling and nucleic acid purification workflows. Select accessories designed for the specific purification platform to ensure proper fit, alignment, and operation.

Deep-well and elution plates

Deep-well plates are used for sample processing and reagent handling, while elution plates are used to collect purified nucleic acids following extraction. Confirm plate format and compatibility with the instrument and workflow requirements before ordering.

Reagent vessels and sample racks

Reagent vessels hold buffers, wash solutions, and other workflow reagents required during automated purification procedures. Sample racks provide organized positioning of vessels and consumables to support efficient workflow setup and operation.

System accessories

Additional accessories, including preconfigured control tablets and demonstration kits, support instrument operation, training, workflow development, and system setup activities.

Specifications Context

Automated purification workflows depend on the correct combination of consumables and instrument accessories. Tip combs, plates, reagent vessels, and racks should be selected according to the instrument model and workflow format to ensure reliable sample handling and purification performance. Routine replacement of consumable components helps maintain workflow consistency and minimizes the risk of cross-contamination.

To discuss product availability or receive guidance on accessory selection, contact the MBP team.

FAQ

Core accessories for automated flash chromatography include prepacked silica or C18 flash cartridges in the gram sizes used most frequently (12 g, 25 g, 40 g, 80 g, and 120 g are the most common), solid loaders for dry sample application, fraction collection tubes and racks matched to the instrument's fraction collector format, UV detector replacement lamps, and (for custom separations) reusable empty glass columns for user-packed stationary phases.

Prepacked flash chromatography cartridges are single-use in most workflows -- the stationary phase is contaminated by sample components and mobile phase residues after each run, and reuse degrades resolution. Empty reusable column hardware (GlasPure-style glass columns) can be repacked with fresh bulk silica multiple times, making them cost-effective for large-scale or high-frequency purifications above 5 g per run. For regulated pharmaceutical workflows, single-use prepacked cartridges are required to ensure batch-to-batch separation consistency.

Normal-phase silica cartridge loading is approximately 1 to 5% of the silica bed mass for routine separations. A 12 g cartridge handles 0.06 to 0.6 g of crude sample; a 25 g cartridge handles 0.12 to 1.25 g; a 40 g cartridge handles 0.2 to 2 g; a 120 g cartridge handles 0.6 to 6 g. For difficult separations with closely similar compounds, reduce the loading to 0.5 to 1% of silica mass to maintain resolution. Overloading beyond 5% of silica mass causes peak broadening and co-elution of adjacent compounds.

A solid loader is a short open-bed tube containing dry silica or Celite onto which the crude sample is adsorbed before loading onto the main flash column. It is used when the sample is not directly soluble in the initial mobile phase composition at the required concentration, or when direct liquid injection causes band broadening at the column head. The adsorbed sample distributes evenly across the stationary phase during loading, improving peak shape. Solid loaders are sized to hold the required sample mass and connect in-line upstream of the main column cartridge.

Flash cartridge compatibility between brands depends on the connector design. Many systems use proprietary cartridge connectors or Luer-lock fittings that are specific to the instrument manufacturer. Some third-party suppliers produce cartridges with universal connectors compatible with multiple instrument platforms, but fit and seal integrity must be verified before use to avoid leaks under pump pressure. Fraction collector tube racks and UV detector lamps are almost always model-specific and must be ordered using the manufacturer's part number.

UV detector lamps in automated flash and preparative HPLC systems typically provide 1,000 to 2,000 operating hours before output decreases to a level that compromises detection sensitivity. Replace the lamp when baseline noise increases, signal intensity at a known compound's UV maximum decreases noticeably, or the instrument's lamp-hours counter reaches the manufacturer's replacement threshold. Continuing to run with a degraded lamp reduces detection of low-UV-absorbing peaks and increases the risk of missed fractions.

Normal-phase silica flash cartridges use a polar stationary phase (silica) and non-polar to mildly polar mobile phases (hexane-ethyl acetate, hexane-acetone) to separate compounds by polarity -- the more polar the compound, the longer it is retained. They are the standard for most synthetic organic chemistry purifications. Reversed-phase C18 flash cartridges use a non-polar bonded stationary phase and polar aqueous-organic mobile phases (water-methanol, water-acetonitrile) to separate compounds by hydrophobicity -- the more hydrophobic the compound, the longer it is retained. Use reversed phase for polar pharmaceutical intermediates, peptides, and compounds that do not elute cleanly on silica.

Yes. MBP provides purchase order procurement for purification system accessories, including flash cartridges, solid loaders, fraction collection consumables, and replacement hardware for research and pharmaceutical laboratories in the USA and Canada. MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center. Contact MBP via the contact page or Quick Order portal with the instrument model and required accessory part numbers for pricing and lead time.

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