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Plate Sealer Accessories: Sealing Films, Foils, and Adapter Kits

Plate sealer accessories are the consumable sealing materials used with heat plate sealers to protect microplate samples from evaporation, contamination, and sample loss during PCR, qPCR, NGS library preparation, and storage. They include optically clear sealing films for PCR and qPCR, aluminum foil seals for secure storage and solvent resistance, and peelable, pierceable, or strong-bond film options for different laboratory workflows. Select a sealing film or foil that is compatible with your plate format, sealing instrument, and downstream application, such as optical detection, cold storage, or DMSO resistance.

MBP provides purchase order procurement for plate sealer accessories for US and Canadian research laboratories. Request a quote by contacting customerservice@mbpinc.net.

Plate Sealer Accessories

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MS1000-F1

Foil seals, peelable for PP plates, 100/pk

List Price:

USD147.80

Online Price:

USD105.57

Your Price:

MS1000-F2

Foil seals, strong bonding for cold storage (-200 to 110°C) and DMSO, for PP plates, 100/pk

List Price:

USD227.06

Online Price:

USD162.19

Your Price:

MS1000-PCR1

Optically clear sealing film for qPCR, Peelable, for most plate types, 100/pk

List Price:

USD227.06

Online Price:

USD162.19

Your Price:

MS1000-PCR3

Optically clear sealing film for qPCR, Pierceable, for most plate types, 100/pk

List Price:

USD227.06

Online Price:

USD162.19

Your Price:

MS1000-PCR2

Optically clear sealing film for qPCR, Strong Bond, for PP plates, 100/pk

List Price:

USD227.06

Online Price:

USD162.19

Your Price:

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What Are Plate Sealer Accessories?

Plate sealer accessories include consumable sealing materials and instrument hardware used with heat plate sealers. Consumable sealing materials, such as sealing films and foil seals, are the most frequently replaced accessories, with one seal used per plate. Films and foils vary in optical properties, adhesion, temperature resistance, and pierceability, making it important to select the appropriate type for PCR, qPCR, sample storage, or automated liquid handling. Instrument hardware accessories, such as sealing frames, adapter inserts, and replacement components, are model-specific and designed to maintain proper sealer performance. Before ordering, confirm whether your application requires an optically clear film, a pierceable foil, or a cryogenic-rated foil.

What You Will Find

Optically clear qPCR sealing films with peelable, pierceable, and strong-bond options.
Peelable sealing films compatible with most microplate types for PCR and qPCR workflows.
Strong-bond sealing films for polypropylene (PP) plates requiring secure sample containment.
Foil plate seals with peelable or strong-bond options for PP plates.
Foil seals suitable for DMSO applications and cold storage from -200°C to 110°C.

How to Choose Plate Sealer Accessories

Seal material: film vs. foil

Polymer films are optically transparent and required for qPCR, fluorescence assays, and plate readers that detect through the seal. They are suitable for thermal cycling and short-term storage. Aluminum foil seals provide superior evaporation protection and are preferred for long-term storage, solvent resistance, and applications that do not require optical read-through.

Optical properties for qPCR

Use optically clear, low-autofluorescence sealing films for real-time qPCR to maximize fluorescence detection sensitivity. Confirm compatibility with your PCR instrument and fluorescence detection wavelengths.

Cryogenic performance

For storage at -80°C or below, select sealing materials designed to maintain adhesion and barrier integrity through repeated freeze-thaw cycles. Cryogenic-rated foil seals provide the most reliable long-term performance.

Pierceable vs. non-pierceable seals

Pierceable foil seals allow robotic or manual pipette access without removing the seal, making them suitable for automated workflows. Non-pierceable seals provide the highest barrier protection for storage but must be removed before accessing samples.

Format adapters and sealing frames

Sealing frames and adapter inserts help align sealing materials and non-standard microplate formats during heat sealing. Verify compatibility with both your plate sealer model and microplate format before ordering.

Specifications Context

Film thickness influences evaporation protection, optical clarity, and piercing performance. Polymer films are typically 60 to 100 micrometers thick, while aluminum foils are generally 50 to 70 micrometers thick. Also confirm whether your plate sealer uses pre-cut sealing sheets or roll-format sealing material, as these formats are not interchangeable.

To discuss product availability or get selection guidance, contact the MBP team.

FAQ

Core plate sealer accessories include sealing films and foils matched to the application (optically clear polymer film for qPCR, aluminum foil for sample storage, pierceable foil for robotic liquid handling), sealing frames that hold the film in position during heat sealing, and format adapter inserts for 384-well and deep-well plates. Replacement instrument components (heating platens, temperature probes, sealing frame springs) are model-specific maintenance items required after extended service life.

Sealing films are transparent polymer materials (polyethylene, polypropylene, or copolymer blends) that allow fluorescence excitation and emission to pass through the seal -- required for real-time qPCR where the detector reads fluorescence through the sealed plate. Sealing foils are aluminum-based, opaque, and reflective -- they provide superior evaporation barrier and cryogenic performance for sample storage at -20 to -80 degrees C but cannot be read through optically. Select film for assays requiring optical access to well contents; select foil for storage and thermal cycling applications where optical transparency is not required.

Some optically clear polymer heat-sealing films are specified for both thermal cycling and short-term storage at -20 degrees C. However, for long-term storage at -80 degrees C, aluminum heat-seal foils with documented cryogenic performance to -80 degrees C are strongly preferred over polymer films, which may become brittle or lose barrier integrity at -80 degrees C over extended storage periods. Check the film manufacturer's stated minimum temperature rating and storage duration specifications before using polymer film for -80 degrees C long-term sample storage.

A pierceable foil seal bonds to the plate rim like a standard heat-seal foil but is formulated to allow a robotic pipette tip or manual pipette needle to pierce through the foil to access individual well contents after sealing -- without removing the entire seal from the plate. Pierceable seals are used in automated liquid handling workflows where the sealed plate is placed on a robotic deck and individual wells are accessed for aliquoting, reformatting, or verification dispensing. Non-pierceable seals provide a stronger barrier for long-term storage but require the entire seal to be removed to access well contents.

For real-time qPCR, select an optically clear heat-sealing film with low autofluorescence at the excitation wavelengths of your fluorescent dyes (typically 470 to 640 nm for multiplex qPCR). Verify that the film is compatible with your qPCR instrument's optical system -- some instruments use top-read optics that detect fluorescence through the seal, while others use side-read or bottom-read optics that may not require optical clarity in the seal. Film manufacturers often list compatible qPCR instruments on their product documentation; use this as a starting point, then validate with a test plate measuring known positive controls.

A sealing frame is a rigid holder that positions a pre-cut sheet of sealing film or foil over the plate, holding it in correct alignment with the plate rim before and during the heat sealing cycle. Without a sealing frame, the film may slip or wrinkle during handling or placement in the sealer, causing misalignment that results in incomplete seals along one or more edges. Most heat plate sealers include a sealing frame matched to the standard 96-well SBS plate footprint; additional sealing frames or adapters are purchased separately for 384-well plates or non-standard plate dimensions.

No. Heat-bonded sealing films and foils form a semi-permanent bond with the plate rim that cannot be cleanly removed and reused. Once peeled from the plate, the film loses its sealing integrity -- re-application does not create a reliable seal. Adhesive seals are also single-use; once removed, the adhesive is contaminated and will not re-seal reliably. For plates that need to be resealed after opening, use a fresh sealing film or foil for each sealing cycle. Maintain an adequate stock of sealing consumables to ensure a fresh seal is available for every plate access.

Yes. MBP provides purchase order procurement for plate sealer accessories including sealing films, aluminum foil seals, sealing frames, and adapter kits for research and pharmaceutical laboratories in the USA and Canada. MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center. Contact MBP via the contact page or Quick Order portal with your sealer model, plate format, and required seal type (optically clear film, aluminum foil, pierceable, or adhesive) for pricing and lead time.

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