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Urine Collection Products for Culture, NAAT, and Nucleic Acid Research

 

Urine collection products for laboratory use range from sterile 30–60 mL cups for culture and urinalysis to preservative-prefilled tubes that stabilize DNA, RNA, and proteins in urine specimens at ambient temperature for 24–72 hours—enabling delayed transport to centralized labs without refrigeration. Format selection depends on downstream application: sterile cups for NAAT and culture (process within 2 hours or refrigerate), boric acid tubes for culture transport up to 24 hours, and nucleic acid preservative tubes for cfDNA liquid biopsy and molecular research.

MBP supplies urine collection products for clinical and research labs across the USA, Canada, and worldwide with direct PO ordering. Request a quote by contacting customerservice@mbpinc.net 

Urine Collection Products

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What are Urine Collection Products?


Urine collection products for laboratory use are containers and preservative systems designed to collect, stabilize, and transport urine specimens for urinalysis (UA), urine culture (C&S), nucleic acid-based testing (NAAT for STIs), cell-free DNA (cfDNA) liquid biopsy, and 24-hour timed collections. Formats include sterile cups (30–60 mL), preservative tubes (5–50 mL), vacuum-draw urine transfer tubes, 24-hour collection containers (2–3 L), and preservative-prefilled devices for ambient-temperature stabilization of DNA, RNA, and proteins. Choose urine collection products with an active preservative when specimens cannot be processed within 2 hours of collection, when samples must be shipped to a centralized lab, or when nucleic acid integrity over 24+ hours is required.

 

What you will find:

 

  • Sterile urine collection containers for routine diagnostic sampling
  • Urine transport tubes for secure handling and transfer workflows
  • Preservative urine tubes for culture and urinalysis stability
  • Midstream urine collection systems for contamination reduction
  • 24-hour urine collection containers for metabolic testing workflows
  • Leak-resistant screw-cap urine tubes for safe transport
  • Graduated urine containers with volume markings for easy measurement
  • Pediatric urine collection solutions for low-volume sampling
  • Closed-system urine transfer devices for reduced exposure handling
  • General laboratory urine collection consumables for research use


How to Choose Urine Collection Products


Application: Culture vs. NAAT vs. Nucleic Acid Research
For culture (C&S), use sterile cups or boric acid preservative tubes. For NAAT (STI panels for Chlamydia, Gonorrhea), use sterile cups or manufacturer-validated transfer tubes; confirm with your platform's IFU (e.g., Hologic Aptima Combo 2 uses a specific urine transport tube). For nucleic acid research (cfDNA, RNA, protein), use dedicated urine preservative tubes (Norgen, Streck) that stabilize analytes for up to 72 hours at room temperature.

Volume: Random vs. 24-Hour Collection
Random midstream urine (10–30 mL) is adequate for urinalysis, culture, and NAAT. Timed 24-hour collections (total volume 500–3000 mL) require large-volume containers with the appropriate preservative for the ordered panel. Mixing 24-hour containers with different preservatives is a common error—verify the correct preservative type with the laboratory before dispensing to the patient.

Preservative Compatibility
Boric acid tubes maintain bacterial counts for culture up to 24 hours at room temperature. Boric acid is NOT compatible with NAAT workflows—it inhibits PCR. For NAAT, use plain sterile containers or manufacturer-specific transfer tubes. For liquid biopsy cfDNA, Streck Cell-Free DNA Urine Preservative maintains cell integrity and prevents genomic DNA contamination for up to 72 hours.

Sterility
All urine containers intended for culture must be certified sterile. Containers for NAAT must be certified DNase-free and RNase-free to prevent nucleic acid contamination from the container. Confirm sterility and nuclease-free certification in the manufacturer's datasheet before use in molecular workflows.

Automated Compatibility
For high-throughput labs using automated urine analyzers (Sysmex UF-5000, Siemens CLINITEK), confirm that the collection tube format and cap design are compatible with tube-handling robotics. Copan UriSponge® (FDA-cleared October 2024) is a boric-acid-free device validated for direct loading on WASP® automation systems.

 

Specifications Context


Standard urine collection cups are manufactured from transparent polypropylene (PP) or polystyrene (PS) with wide-mouth, screw-cap lids. Sterile cups rated for culture meet ISO 7886 and are non-pyrogenic. Boric acid preservative tubes contain approximately 1.8% boric acid, stabilizing bacterial counts by creating a bacteriostatic environment. Norgen urine preservative tubes (5–50 mL, available in multiple sizes) stabilize DNA, RNA, microRNA, and protein from fresh urine for over 2 years at room temperature per manufacturer validation data. As of 2026, liquid biopsy studies using urine cfDNA routinely use Streck Cell-Free DNA Urine Preservative (3 mL per 30 mL urine) as the standard stabilization protocol in published clinical research protocols.

Need help picking the right urine collection setup? Contact MBP, and we’ll help you sort it out fast. No confusion, just the right fit for your workflow.

FAQ

Laboratory urine collection products include sterile cups (30–60 mL, for culture, UA, and NAAT), boric acid preservative tubes (5–10 mL, for culture with delayed transport up to 24 hours), nucleic acid preservative tubes (5–50 mL, for cfDNA and RNA liquid biopsy up to 72 hours at room temperature), 24-hour collection containers (2–3 L, for timed chemistry panels), and platform-specific transfer tubes for STI NAAT assays.
Urine without a preservative should be processed within 2 hours of collection; refrigeration at 2–8 °C extends this to approximately 24 hours before significant cellular degradation and bacterial growth occur. Boric acid preservative tubes extend culture stability to 24 hours at room temperature. Nucleic acid urine preservative tubes (Norgen, Streck) maintain DNA, RNA, and protein integrity for up to 72 hours at ambient temperature.
No. Boric acid is a known PCR inhibitor and should not be used in urine collection for NAAT-based assays such as Chlamydia/Gonorrhea testing (Hologic Aptima, Abbott RealTime). Use sterile cups or manufacturer-validated transfer tubes specifically cleared for the target platform's NAAT workflow. Mixing boric acid tubes with molecular assays is a common cause of false-negative results.
Cell-free DNA (cfDNA) liquid biopsy from urine requires a preservative that stabilizes cells in suspension (preventing lysis and genomic DNA release) while protecting cfDNA fragments. Streck Cell-Free DNA Urine Preservative (added at 3 mL per 30 mL of urine) maintains urine sample integrity for up to 72 hours at room temperature and is used in published clinical liquid biopsy protocols.
A 24-hour urine collection begins with the patient discarding the first morning void, then collecting all subsequent urine for exactly 24 hours including the first void of the following morning. The entire volume is measured in mL, recorded on the requisition form, and an aliquot submitted to the laboratory. The correct preservative (boric acid, hydrochloric acid, or thymol) must be pre-added to the container based on the specific chemistry panel ordered.
Urine cups intended for culture (C&S) must be certified sterile and non-pyrogenic, meeting ISO 7886 standards for specimen containers. Cups for NAAT applications must additionally be certified DNase-free and RNase-free to prevent nucleic acid contamination. Always verify the sterility and nuclease-free certification on the manufacturer's datasheet before use in culture or molecular workflows.
Sterile cups without preservative and boric acid tubes should be shipped refrigerated to preserve sample integrity. Nucleic acid urine preservative tubes (Norgen 5–50 mL format) are stable for 72 hours at ambient temperature, enabling room-temperature courier shipping for liquid biopsy and molecular testing programs. Confirm the specific stability window with the manufacturer's datasheet for the preservative format you use.
MBP accepts purchase orders for bulk urine collection product procurement, including sterile cups, preservative tubes, and NAAT transfer containers, with direct human support for institutional quotes. Contact MBP for case pricing on large-volume orders for hospitals, clinical laboratories, and research programs across the USA, Canada, and worldwide.
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