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KingFisher Flex Consumables for Automated DNA, RNA, Protein, and Cell Purification

 

KingFisher Flex consumables are polypropylene 96-well deep well plates and tip combs manufactured by Thermo Scientific for automated magnetic bead-based purification of DNA, RNA, proteins, and cells on KingFisher Apex, Flex, Duo Prime, and Presto instruments. The 96-well deep well format supports 100–1,000 µL input per well; 24-well plates handle up to 5 mL. Instrument-specific plate and tip comb geometry is required for reproducible bead capture and transfer. MBP supplies KingFisher consumables to labs across the United States, Canada, and internationally.

Need help selecting the right KingFisher Flex consumables for your purification workflow? Contact customerservice@mbpinc.net for product recommendations, pricing, and procurement support.

Kingfisher Flex Consumables

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What Are KingFisher Flex Consumables?

 

KingFisher Flex consumables are specialized plates, tip combs, and accessories designed specifically for Thermo Scientific KingFisher magnetic particle processors, including the KingFisher Flex, Apex, Duo Prime, and Presto systems. These consumables are engineered to support automated magnetic bead-based purification workflows for DNA extraction, RNA isolation, protein purification, cell isolation, and other molecular biology applications. Their precise dimensions and well geometries ensure accurate magnetic rod movement, efficient bead transfer, and consistent purification results across high-throughput laboratory workflows.

Unlike standard deep well plates, KingFisher consumables are manufactured from low-binding polypropylene to minimize the loss of nucleic acids and proteins during extraction and washing steps. This helps maximize sample recovery, improve purity, and maintain reproducibility in research, clinical diagnostics, biobanking, and next-generation sequencing (NGS) applications.

 

At MBP, You can discover:

 

  • 6 Deep-Well Plates for KingFisher Flex and Presto systems

  • 24-Well Deep Well Plates for high-volume extraction

  • 96-Format Plastic Tip Combs for magnetic bead collection

  • U-bottom Square Well Plates for minimal volume

  • 10.4 ml 24-well plates for large-scale purification

  • Medical-grade Polypropylene Plates for chemical stability

  • Sterile, DNase/RNase-free consumables for sensitive assays

  • High-recovery extraction plates for maximum specimen yield

 

How to Choose KingFisher Flex Consumables

 

Instrument Configuration

Consumable selection depends on the instrument model and processing head installed. Most KingFisher Flex systems use a 96-well head designed for medium-throughput sample processing, while certain applications require a 24-well head for larger sample volumes. Always verify your instrument configuration before ordering consumables.

 

Sample Volume Requirements

The 96-well format is ideal for routine DNA and RNA extraction from blood, plasma, swabs, tissue lysates, and cultured cells. Applications requiring larger input volumes, such as circulating cell-free DNA isolation, environmental testing, or stool sample processing, often use the 24-well format, which accommodates significantly larger volumes per well.

 

Sterility Requirements

Non-sterile consumables are commonly used for standard nucleic acid purification and protein extraction workflows. Sterile plates and sterile plate-tip comb combination packs are recommended for cell-based applications, sensitive RNA workflows, and any procedure requiring aseptic processing conditions.

 

Individual Components vs. Combination Packs

Many laboratories purchase plates and tip combs separately to match workflow requirements. Combination packs containing both sterile plates and matching sterile tip combs simplify inventory management and ensure compatibility between components.

 

Downstream Application

For PCR, qPCR, sequencing, and library preparation workflows, purified samples are typically transferred into 96-well microplates with smaller working volumes. Applications requiring larger elution volumes may use deep well plates for the final collection step.

 

Common KingFisher Flex Consumable Formats

 

KingFisher workflows commonly use 96-well deep well plates for routine magnetic bead extraction, paired with matching 96-tip combs that facilitate bead capture and transfer throughout the purification process. Larger-volume workflows utilize 24-well deep well plates and corresponding tip combs. Additional accessories include elution plates, storage plates, and sterile combination packs that streamline automated extraction workflows.

 

Specifications Context

 

KingFisher consumables are manufactured from high-purity, low-binding polypropylene to reduce non-specific adsorption of DNA, RNA, proteins, and magnetic beads. They are produced under strict quality control standards to ensure dimensional consistency and compatibility with automated magnetic particle processors.

These consumables are widely used in molecular diagnostics, genomics, biobanking, pharmaceutical research, and clinical laboratories. Their standardized design supports reproducible extraction performance while maintaining compatibility with automated sample preparation workflows.

For laboratories requiring more general automation-compatible sample processing plates, deep well plates provide SBS-format compatibility with liquid handling systems from Hamilton, Tecan, Beckman Coulter, and other automation platforms. Immunoassay and ELISA workflows, however, require specialized assay plates designed for optical detection rather than magnetic bead processing. 

Lock your combs, load your plates, and let the automation handle the precision. Request a quote from the team at Molecular Biology Products Inc today.

FAQ

KingFisher Flex consumables are polypropylene deep well plates and tip combs manufactured by Thermo Scientific specifically for the KingFisher Flex, Apex, Duo Prime, and Presto magnetic bead processors. Instrument-specific plastics are required because the well geometry, plate depth, and tip comb dimensions are precisely engineered to match the magnetic rod travel path and bead transfer mechanics of each KingFisher head format — standard lab plates cannot reliably capture and transfer magnetic beads with equivalent yield and purity.
A standard KingFisher Flex run with the 96 deep well head requires: KingFisher 96 deep-well plate (Cat. No. 95040450), KingFisher 96 tip comb for deep-well (Cat. No. 97002534), a KingFisher 96 microplate 200 µL for elution (Cat. No. 97002540), and a KingFisher 96 tip comb for the microplate (Cat. No. 97002524). A sterile combi-pack (plate + tip comb, Cat. No. 97002820) is available for workflows requiring sterile conditions.
KingFisher 96 deep-well plates support sample input volumes from 100 µL to 1,000 µL per well, compared to 20–200 µL in the standard (200 µL) microplate format. The 24-well deep-well format for the KingFisher Flex supports processing volumes up to 5 mL per well for larger-input nucleic acid extractions such as plasma, stool, or environmental samples.
Polypropylene is specified for KingFisher consumables because of its low non-specific binding affinity for DNA, RNA, and proteins — critical for magnetic bead workflows where non-specific surface adsorption reduces yield and purity. Polypropylene also withstands the chaotropic salts, detergents, and ethanol washes in standard nucleic acid extraction buffers without surface degradation or leaching.
KingFisher 96 deep-well plates and tip combs are compatible with KingFisher Apex, KingFisher Flex, KingFisher Duo Prime, and KingFisher Presto instruments. Thermo Scientific specifies compatibility across all four platforms for the 96 deep well head format. The MagMAX Express-96 magnetic head also accepts the same 96-well tip combs as the KingFisher Flex.
Standard deep well plates can be used as a manual alternative with a magnetic stand if the KingFisher protocol is modified, but Thermo Scientific states that yield, purity, and reproducibility are significantly improved with KingFisher-optimized plastics. Tip comb geometry is proprietary and not compatible with standard deep well plate dimensions from other manufacturers. For validated workflows, instrument-specific consumables are the recommended choice.
KingFisher Flex consumables are used in automated magnetic bead-based purification of DNA (genomic, plasmid, cfDNA), RNA (total, mRNA, miRNA), proteins, and cells from sample types including blood, plasma, serum, tissue, swabs, and environmental matrices. Applications include next-generation sequencing library prep, clinical diagnostics sample processing, biobank extraction at scale, and CRISPR reagent purification.
MBP supplies KingFisher Flex-compatible consumables to labs in the United States, Canada, and internationally. For specific catalog numbers, case pricing, or PO-based procurement, contact MBP through the Quick Order tool or inquiry form at mbpinc.net. MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, MD Anderson Cancer Center, and Eurofins.
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