Brands

<h2>What Are Nucleases?</h2>
&nbsp;
Nucleases are enzymes that cleave phosphodiester bonds between nucleotide subunits in nucleic acids. Deoxyribonucleases (DNases) act on DNA; ribonucleases (RNases) act on RNA; and some nucleases (S1 Nuclease, Mung Bean Nuclease) act on both single-stranded DNA and RNA. Nucleases are further divided into endonucleases, which cleave internal phosphodiester bonds, and exonucleases, which progressively remove nucleotides from the 5' or 3' terminus of a strand. Major research nucleases include DNase I (non-specific endonuclease for both ss- and ds-DNA), RNase A (cleaves single-stranded RNA at pyrimidine residues), RNase H (degrades the RNA strand of RNA: DNA hybrids), Exonuclease III (removes nucleotides from 3'-recessed or blunt ends of duplex DNA), S1 Nuclease (degrades single-stranded DNA or RNA), and RNase R (degrades linear RNA but not circular RNA). Match the nuclease to the substrate type (single-stranded vs. double-stranded, DNA vs. RNA), the directionality required (endo vs. exo), and cofactor compatibility with your reaction buffer.
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<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" aria-level="1">
PureRec RNase A (Recombinant): A ribonuclease free of animal-derived components, designed for the swift elimination of RNA from DNA samples, ensuring no threat of viral contamination.
</li>
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DNase I Set (RNase-free): A highly effective endonuclease formulated for complete DNA digestion in delicate RNA applications while preserving the integrity of the transcript.
</li>
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PureRec Duplex-Specific Nuclease (DSN): A unique enzyme designed to equalize high-abundance transcripts, greatly enhancing the identification of rare variants in cDNA libraries.
</li>
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RNase R: A distinctive 3'-to-5' exoribonuclease that breaks down linear RNA but preserves circular RNA forms, crucial for the identification of circRNA.
</li>
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RNaseOFF Inhibitor: A strong protein-based barrier that counteracts a wide range of RNases, maintaining the delicate transcriptional environment of your samples.
</li>
</ul>
&nbsp;
<h2>How to Choose Nucleases</h2>
&nbsp;
DNase selection
DNase I (bovine pancreatic, recombinant) non-specifically cleaves both single- and double-stranded DNA in the presence of Mg2+ (random cleavage) or Mn2+ (double-strand cuts at approximately the same position on both strands). Use RNase-free DNase I for RNA preparations to remove genomic DNA contamination. Use Plasmid-Safe ATP-Dependent DNase to selectively degrade linear double-stranded DNA while preserving supercoiled and relaxed circular plasmid DNA. Baseline-ZERO DNase is optimized for the complete removal of trace DNA without damaging RNA.
RNase selection
RNase A cleaves single-stranded RNA at pyrimidine (C and U) residues to produce 3'-pyrimidine nucleotides; it is used to remove RNA from DNA preps, to perform RNase protection assays, and to analyze RNA secondary structure. RNase H degrades the RNA strand of RNA: DNA duplexes and is used after first-strand cDNA synthesis to remove the mRNA template. RNase R (3'-&gt;5' exoribonuclease) degrades all linear RNA without affecting circular RNA, and is used in circular RNA enrichment workflows and to characterize circular RNA splice junctions. Terminator 5'-Phosphate-Dependent Exonuclease (Terminator) digests linear RNA with a 5'-monophosphate, enriching for capped mRNA or circular RNA.
Exonuclease selection
Exonuclease III (Exo III) removes nucleotides from the 3' terminus of duplex DNA and generates single-stranded regions used in unidirectional nested deletions, mapping regulatory elements, and generating single-stranded templates for sequencing. Exonuclease I (Exo I) digests single-stranded DNA in the 3'-&gt;5' direction and is used after PCR to remove unincorporated primers before Sanger sequencing. Lambda Exonuclease removes nucleotides from 5'-phosphorylated duplex DNA in the 5'-&gt;3' direction and is used in isothermal amplification and strand displacement workflows.
Cofactor and inhibitor sensitivity
DNase I requires Mg2+ or Ca2+ for activity and is completely inhibited by EDTA at a 5 mM concentration. RNase A is active across a wide pH range (optimum 7.0-7.5) and is exceptionally stable; inactivation requires proteinase K digestion, phenol-chloroform extraction, or RNase inhibitor protein. RNase H requires Mg2+; RNase R requires Mg2+ and is most active between 37-50 degrees C.
Purity and application grade
For RNA-focused applications, all nucleases used on DNA substrates must be certified RNase-free. For DNA-focused work, DNase-free grades of RNases are required. Confirm lot-specific QC contamination data from the manufacturer before use in sensitive workflows.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
DNase I activity is expressed in Kunitz units: 1 unit increases A260 by 0.001 per minute per mL during DNA hydrolysis at pH 5.0. RNase A activity is expressed as the amount of enzyme hydrolyzing 50% of an RNA substrate under defined conditions; it remains active at a wide range of temperatures and is notoriously difficult to inactivate (requires boiling in SDS, proteinase K digestion, or phenol-chloroform extraction). RNase R from E. coli degrades linear RNA processively in the 3'-&gt;5' direction and is used at 2-10 U per microgram of total RNA to enrich for circular RNA species. RNase R treatment before library construction is the standard method for circular RNA sequencing (circRNA-seq) workflows on both short-read and long-read platforms. For protecting RNA from RNase contamination during nuclease-adjacent workflows, see&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/enzymes-and-inhibitors">RNase inhibitors</a>&nbsp;in the parent Enzymes and Inhibitors category.
&nbsp;
Safeguard your molecular images&mdash;<a href="https://mbpinc.net/contact-us">reach out to the MBP team</a> now to obtain a quote for our sophisticated nucleases and inhibitors.

Nucleases

MSDS

RNase A Solution

RNase A Solution G118 — 10 mg/ml, 1.0 ml. Cleaves single-stranded RNA at C and U residues. For RNA removal from plasmid DNA preparations, RNase protection assays, and cell lysate processing. Working concentration determined by end user. Store at −20 °C.

Unit Quantity

Concentration

Storage Condition

Shipping condition

DataSheet

RNase R

E049 by Applied Biological Materials is recombinant E. coli RNase R at 10 U/µL, supplied as 500 U (50 µL) with 10× Reaction Buffer. 3′-to-5′ exonuclease degrades linear RNA; leaves circRNA, lariat RNA, and dsRNA (&lt;7 nt overhang) intact. For circRNA enrichment, lariat identification, and splicing studies. Store at −20°C; stable 1 year.

Format General

Expression System General

Reaction Definition

Reaction Buffer

Storage Buffer

Note

Caution

Shipping Condition

RNase R with RNaseOFF Bundle

E049-G138 by Applied Biological Materials is the RNase R with RNaseOFF Bundle: E049 RNase R (500 U, 10 U/µL; degrades linear RNA, spares circRNA/lariat) + G138S RNaseOFF Ribonuclease Inhibitor (800 U, 40 U/µL; RNA protection). Complete reagent pair for circRNA enrichment and lariat RNA research. Store at −20°C.

Certificate of Analysis

Flyer

RNaseOFF Ribonuclease Inhibitor Product Testing Report

RNaseOFF Ribonuclease Inhibitor

G138 by Applied Biological Materials is RNaseOFF Ribonuclease Inhibitor, supplied at 40 U/µL as 4,000 U (100 µL). Inhibits RNase A, B, and C with no polymerase inhibition. Enhanced oxidation resistance; stable at DTT &lt;1 mM and at 70°C. For RT-PCR, RT-qPCR, IVT, cDNA synthesis, and RNA storage. Larger format available as G591.

G591 by Applied Biological Materials is RNaseOFF Ribonuclease Inhibitor — 100,000 U (2 × 1.25 mL) at 40 U/µL. Inhibits RNase A, B, and C; no polymerase inhibition; oxidation-resistant; stable at &lt;1 mM DTT and 70°C. For RT-PCR, in vitro transcription, cDNA synthesis, RNA storage. Smaller size: G138. Store at −20°C.

<h2 data-section-id="185nm5c" data-start="0" data-end="38">What is classic cell culture media?</h2>
&nbsp;
Classic cell culture media refers to the foundational basal medium formulations that have underpinned mammalian cell culture for decades, including DMEM (Dulbecco's Modified Eagle Medium), MEM (Minimum Essential Medium), RPMI 1640, Ham's F-10, Ham's F-12, IMDM (Iscove's Modified Dulbecco's Medium), and DMEM/F-12. These media provide the amino acids, vitamins, glucose, salts, buffering agents, and other nutrients required to support cell survival and growth in vitro. They form the basis of many modern specialized, serum-free, and advanced media formulations used in academic research, biotechnology, pharmaceutical development, and biomanufacturing.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" aria-level="1">
&nbsp;Availability of both low and high carbohydrate levels of balanced basal formulations for the distinct metabolic requirements of diverse mammalian cell lines.
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Maintenance of precise physiological pH during long-term incubation cycles using optimized buffering configurations with integrated chemical stabilizers&nbsp;
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Nutrient-dense cell media supplemented with vitamins and essential amino acids to support&nbsp; hybridomas and rapidly proliferating continuous cultures
</li>
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Optimized serum reduction along with enhanced cell attachment using&nbsp;Multi-purpose 1:1 formulation hybrids&nbsp;
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Salt solutions supplemented with essential minerals to facilitate enzyme preparation, cell washing, and reliable short-term osmotic maintenance.
</li>
</ul>
&nbsp;
<h2 data-section-id="1blio5n" data-start="931" data-end="964">How to choose a classic medium</h2>
&nbsp;
DMEM vs MEM
DMEM contains up to four times the amino acids and vitamins found in MEM, along with higher glucose concentrations, making it suitable for cell types with elevated nutrient demands. It is widely used for primary cells, stem cells, and many transformed mammalian cell lines. MEM, based on the original Eagle's formulation, remains a common choice for standard monolayer culture and is available with different salt formulations to support various applications.
RPMI 1640 for suspension and hematopoietic culture
RPMI 1640 was originally developed for culturing human leukemic cells and remains the preferred medium for lymphocytes, hybridomas, and other hematopoietic cell types. Its formulation includes glutathione and elevated levels of biotin, vitamin B12, and PABA. Although designed for suspension cultures, RPMI 1640 also supports a wide range of adherent cell lines when appropriately supplemented.
Ham's F-10/F-12 for CHO and specialized applications
Ham's nutrient mixtures were developed for CHO cells and other specialized cell types. Their formulations include additional nutrients such as zinc, putrescine, hypoxanthine, and thymidine, making them useful for hepatocyte culture, toxicity testing, viral fusion studies, and other specialized applications. These media can be used with or without serum depending on the experimental requirements.
DMEM/F-12 for complex, rich-medium applications
DMEM/F-12 combines the nutrient-rich composition of DMEM with the specialized components found in Ham's F-12. The resulting formulation supports demanding cell types including MDCK cells, glial cells, fibroblasts, and endothelial cells. It is also widely used as the foundation for many serum-free and advanced culture systems.
IMDM for high-density rapid proliferation
IMDM is an enriched derivative of DMEM that contains additional amino acids, vitamins, HEPES buffer, sodium pyruvate, and potassium nitrate. Its enhanced nutrient profile makes it particularly suitable for rapidly proliferating and high-density cultures such as Jurkat cells, COS-7 cells, and macrophages.
Liquid vs powder format
Liquid classic media are supplied ready for use after the addition of serum and required supplements. Powdered media offer lower shipping costs and greater flexibility for high-volume laboratories but require reconstitution, sodium bicarbonate addition, and sterile filtration before use.
&nbsp;
<h2 data-section-id="1fljvas" data-start="4382" data-end="4407">Specifications context</h2>
&nbsp;
Classic media are manufactured according to their original published formulations, with only stability-related modifications where necessary. Most liquid formulations contain sodium bicarbonate as the primary buffering system and require incubation in a 5&ndash;10% CO₂ atmosphere to maintain physiological pH. Powdered formulations require reconstitution, sodium bicarbonate supplementation, and sterile filtration before use.
As of 2026, DMEM, DMEM/F-12, and RPMI 1640 remain the most widely used classic cell culture media across academic, biotechnology, pharmaceutical, and biomanufacturing laboratories. IMDM continues to gain popularity for high-density culture and bioprocessing applications.
For recombinant growth factors and cytokines used alongside classic media, see Recombinant Proteins. For supplementation reagents such as GlutaMAX, NEAA, sodium pyruvate, and HEPES, see Cell Culture Supplements &amp; Additives. Browse Mammalian Cell Culture for the broader category.
<a href="https://mbpinc.net/contact-us">Contact the expert team</a> at MBP today and get optimized classic media for your lab.

Classic Media

RPMI 1640 Medium

RPMI 1640 Medium (TM503) by Applied Biological Materials is a 500 ml sterile basal medium containing L-glutamine, sodium bicarbonate (2.0 g/L), and phenol red (no HEPES) for culture of Jurkat, MCF-7, HeLa, PBMC, astrocytes, and carcinoma lines. Supplement with 10% FBS; requires 5–10% CO₂. Store at 2–8°C, protected from light.

Sterility

Appearance

Disclaimer

<h2>What are epigenetics NGS library preparation kits?</h2>
&nbsp;
Epigenetics NGS library preparation kits convert the DNA output of an upstream epigenetics workflow into an indexed sequencing library: adapters are ligated to the ends of each DNA fragment, an optional amplification step increases the total amount of library, and indexes are added to allow multiplexed sequencing of many samples in a single run. These kits are specifically optimized for epigenetics-specific inputs, including ChIP-enriched DNA (often low-yield, sheared to 200&ndash;750 bp), chromatin-accessible DNA from ATAC-seq (also low-yield and fragmented), and bisulfite-converted DNA (fragmented and chemically modified, with low-complexity sequence).
&nbsp;
<h2 dir="ltr">What You Will Discover:</h2>
&nbsp;
<ul>
<li dir="ltr">Groundbreaking single-tube processes that integrate bisulfite conversion and library preparation to chart entire genomes with extremely low input needs.</li>
<li dir="ltr">Rapid, efficient transposase-driven methods that seize open chromatin areas and dynamic regulatory environments in only a few hours.</li>
<li dir="ltr">Enzymatic restriction methods combined with targeted sequencing for affordable, high-density CpG coverage without incurring full-genome expenses.</li>
<li dir="ltr">Advanced multi-adapter ligation techniques designed to reduce bias and optimize library retrieval from fragmented or challenging DNA sources.</li>
<li dir="ltr">Post-bisulfite library preparation systems designed explicitly for sub-nanogram DNA quantities, individual cells, or extensively degraded specimens.</li>
<li dir="ltr">Locus-specific, genome-wide enrichment approaches aimed at accurately monitoring and characterizing 5-hydroxymethylcytosine alterations throughout the genome.</li>
</ul>
&nbsp;
<h2>How to choose epigenetics NGS library preparation kits</h2>
&nbsp;
Match your library prep kit to your specific epigenetics input type
ChIP-seq library prep kits are optimized for low-yield sheared chromatin enriched by immunoprecipitation, while ATAC-seq kits work with tagmented open chromatin fragments, and bisulfite or enzymatic methyl-seq library prep kits are specifically formulated for the highly fragmented, low-complexity sequence characteristics of bisulfite-converted DNA input.
Confirm the kit supports your input DNA amount
ChIP experiments, especially those targeting low-abundance transcription factors or run from limited cell numbers, often yield very little enriched DNA, and kits validated for low-input or picogram-scale library preparation are necessary to generate libraries with sufficient complexity without excessive PCR amplification introducing duplicates.
Choose an indexing strategy appropriate to your sample multiplexing plan
Dual-index strategies, using unique combinations of two distinct index sequences per sample, provide more reliable sample demultiplexing in highly multiplexed runs compared with single-index strategies, and confirming whether your kit supports the number of samples and multiplexing depth required is an important selection criterion.
Understand the impact of PCR cycles on library complexity and duplicate rate
Fewer PCR amplification cycles reduce the proportion of duplicate reads in sequencing data, which is especially important for low-complexity epigenetics libraries where overamplification can dominate output with copies of the same original fragment. Efficient ligation chemistry that increases library yield from low input helps minimize required PCR cycles.
Confirm kit compatibility with your downstream analysis pipeline
Some library prep protocols use specific adapter sequences or library structures that require corresponding adjustments in bioinformatics analysis pipelines, and confirming compatibility before sequencing helps avoid downstream analysis failures.
&nbsp;
<h2>Specifications context</h2>
&nbsp;
ChIP-seq library prep kits optimized for low-input or ultra-low-input chromatin are designed to achieve high library complexity from picogram-scale DNA inputs that would otherwise produce low-complexity libraries with standard kits at similar PCR cycle numbers. As of 2026, library prep kits compatible with enzymatic methyl-seq (EM-seq) as well as classical bisulfite-converted DNA continue to expand, enabling researchers to leverage improved DNA quality while maintaining familiar downstream sequencing workflows.
Prepared to enhance your sequencing efficiency? Discover our complete selection of NGS Library Preparation Kits and <a href="https://mbpinc.net/contact-us">contact the MBP team</a> for a quote now.

NGS Libray Preparation Kits

Protocol

RRHP 5-hmC Library Prep Kit

The RRHP 5-hmC Library Prep Kit (D5450) by Zymo Research enables reduced representation hydroxymethylation profiling of 5-hmC in 12 reactions, using an enzymatic—not bisulfite—approach for genome-wide 5-hmC mapping compatible with Illumina HiSeq and MiSeq platforms.

Equipment Required

Input

Sample Source

Sequencing Compatibility

Manufacturer

RRHP™ 5-hmC Library Prep Kit (12 Preps.)

RRHP™ 5-hmC Library Prep Kit (25 Preps.)

Dispenser Syringe Tips

3920S-Group-RV-Pette PRO Brochure

RV-Pette PRO Dispenser Syringe Tips, Sterile

3920S by Globe Scientific — certified sterile RV-Pette PRO™ dispenser tips, 0.05 mL per stroke. RNase-free, DNase-free, ATP-free, pyrogen-free. Box of 100. For non-sterile workflows, see SKU 3920. Available from MBP Inc. worldwide.

Manufacture

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 0.05mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 0.1mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 0.2mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 0.5mL, CS/2000

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 1.0mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 1.25mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 2.5mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 5mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 10mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 12.5mL, CS/1600

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 25mL (1 Red Adapter Included), CS/400

RV-Pette PRO Dispenser Tip for Repeat Volume Pipettors, Certified, Sterile, 50mL (1 Gray Adapter Included), CS/400

Vortex Mixers Accessories

<h2>What are vortex mixer accessories?</h2>
&nbsp;
Vortex mixer accessories are the interchangeable cup heads, foam inserts, and platform adapters that convert a standard single-tube vortex mixer to batch-process multiple tubes or different vessel formats simultaneously. The standard single-tube cup head can be replaced with a multi-tube foam insert holding 6 to 24 microcentrifuge tubes, a tube strip or microplate adapter, or a platform-style attachment for larger vessel formats. These accessories are typically instrument-specific, using a proprietary attachment mechanism that varies between vortex mixer brands.&nbsp;
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Tube racks for 0.5 ml, 1.5/2.0 ml, 12 mm, 13 mm, and 15 ml tubes</li>
<li dir="ltr" role="presentation">High-capacity tube racks for holding up to 96 samples</li>
<li dir="ltr" role="presentation">Horizontal heads for mixing 2 &times; 50 ml tubes and 4 &times; 15 ml tubes</li>
<li dir="ltr" role="presentation">Foam tube holders for 6 mm, 10 mm, 12 mm, and 16 mm tubes</li>
</ul>
&nbsp;
<h2>How to choose vortex mixer accessories</h2>
&nbsp;
Select foam inserts by the tube format they accommodate
Foam inserts for vortex mixers are sized to hold specific tube formats by pressing the closed tube caps into the foam at defined positions: standard microcentrifuge inserts hold 1.5 mL and 2 mL tubes, larger foam blocks accommodate 15 mL and 50 mL conical tubes, and low-profile inserts hold 0.5 mL tubes or PCR strip tubes in defined arrays. Check that the insert format matches the tube types you use most and that the insert is rated for your vortex mixer's speed range.
Confirm accessory compatibility with your vortex mixer model
Vortex mixer accessories attach via model-specific connectors &mdash; threaded onto the drive spindle or clipped onto the instrument head &mdash; and are not universally compatible between brands or models. Always check that the specific accessory is listed as compatible with your vortex mixer model before ordering.
Use a microplate adapter for 96-well plate mixing
Microplate vortex adapters replace the standard cup head with a flat or recessed platform sized to hold a standard 96-well plate, allowing entire plates to be mixed in continuous mode for ELISA plate washing steps, microplate cell resuspension, and plate-format biochemical assays. The adapter should be rated for the speed at which it will be used to prevent plate sliding.
Check that foam insert speed ratings are compatible with your operating speed
Foam inserts are rated for a maximum operating speed, and using a foam insert at speeds above its rating risks tubes not being securely retained by the foam compression at high rpm. Confirm that the insert's rated speed covers your intended operating speed before batch-processing valuable samples.
Consider a universal platform adapter for flexible use
Some vortex mixer manufacturers offer a universal platform adapter that replaces the cup head with a flat non-slip platform, accepting a wide range of vessel formats using a non-slip mat for retention. While less format-specific than a dedicated foam insert, a universal platform provides flexibility for less common vessel formats.
&nbsp;
<h2>Specifications context</h2>
&nbsp;
Foam inserts work by compressing foam around tube caps to provide frictional retention during high-speed oscillation; foam material and cell size determine tube sizes accommodated and maximum safe speed. As of 2026, inserts accommodating PCR strip tubes alongside microcentrifuge tubes in a single insert have become available, reducing the number of separate formats needed.
<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> today to request a quote and find the right accessories for your vortex mixer.

Vortex Mixer Accessories

Rack for 96 x 0.2ml tubes or strips (3pk)

BV1010-MP02 by Benchmark Scientific is a pack of 3 carriers for 96 x 0.2 mL PCR tubes or strip tubes, designed to load into the BV1010-MP multiplate rack on BenchMixer XL vortex mixers (BV1010 and BV1010-TST). The BV1010-MP parent rack is required and sold separately.

Rack for up to 3 microplates

BV1010-MP by Benchmark Scientific is an optional rack for up to 3 standard microplates, designed to mount on the BenchMixer XL (BV1010) and BenchMixer XLQ (BV1010-TST) platforms for simultaneous multi-plate vortexing.

Filtered Pipette Tips

<h2 dir="ltr"> What Are Filtered Pipette Tips?</h2>
 Filtered pipette tips contain a hydrophobic aerosol-barrier plug &mdash; polyethylene (PE) frit or cellulose &mdash; embedded inside the tip body, positioned to intercept aerosol and liquid that would otherwise travel up through the tip collar into the pipette barrel during dispensing or when handling volatile or splashing samples. The filter protects the pipette barrel from internal contamination (which requires costly professional decontamination) and protects samples from cross-contamination by previously deposited nucleic acids, proteins, or biohazardous material in the barrel. Filtered tips are the standard consumables for PCR and qPCR setup, RNA extraction, cDNA synthesis, working with radioactive or biohazardous agents, and any workflow where a single contaminated barrel could compromise a run or an experiment. Non-filtered tips remain appropriate for routine buffer, media, and reagent dispensing where cross-contamination through the barrel is not a concern. Use filtered tips for all nucleic acid work, PCR, and biohazardous samples; use standard tips for routine buffer and reagent dispensing.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li><a href="https://mbpinc.net/consumables/liquid-handling-products/pipette-tips/universal-fit-pipette-tips" title="Universal Fit Filter Tips">Universal Fit Filter Tips:</a> &ndash; Designed to fit a wide range of standard pipettes, with options including wide-bore, low-retention, sterile, RNase/DNase-free, and aerosol barrier formats to support diverse liquid handling applications while maintaining sample integrity.</li>
<li><a href="https://mbpinc.net/consumables/liquid-handling-products/filtered-pipette-tips/lts-compatible-filter-tips" title="LTS Compatible Filter Tips:">LTS Compatible Filter Tips:</a>&nbsp;Optimized for high-performance pipetting systems, featuring extended-length and rack-packed configurations for deep-vessel access, with bulk-pack options available to support reliable, high-throughput laboratory workflows.</li>
</ul>
<h2 dir="ltr"> How to Choose Filtered Pipette Tips</h2>
 Filter Material: Polyethylene Frit vs Cellulose Hydrophobic PE frits are the most common and most studied aerosol-barrier material; they block liquid ingress reliably without absorbing sample material or releasing fibres. Cellulose filters are used in some barrier tips (including the original Thermo Barrier tips); they are effective aerosol barriers but can absorb a small volume of aqueous sample, relevant at &le;10 &micro;L, where the absorbed volume is proportionally significant.
Universal Fit vs LTS-Compatible Filtered Tips Universal filtered tips use standard collar geometry (3.8 mm for &le;10 &micro;L, 6.1 mm for &le;200 &micro;L) and fit Eppendorf, Rainin Classic (non-LTS), and Thermo pipettes. LTS-compatible filtered tips use Rainin's cylindrical LTS mounting geometry and are required for Rainin LTS pipettes.&nbsp;
Low-Retention Filtered Tips Low-retention filtered tips combine an aerosol barrier with a hydrophobic inner tip wall, reducing liquid adhesion during dispensing. They are recommended for small-volume (&le;10 &micro;L) nucleic acid work, RNA, protein, and enzyme dispensing, where both contamination protection and volume accuracy are critical.
Volume Range Filtered tips are available across 10 &micro;L (P2&ndash;P10), 20 &micro;L (P20), 100 &micro;L (P100), 200 &micro;L (P200), 300 &micro;L, 1,000 &micro;L (P1000), and 1,250 &micro;L extended formats. Extended-length filtered tips reach deep into 15 mL and 50 mL conical tubes for nucleic acid elution and sample transfer steps.
Packaging Filtered tips are typically sterile-racked (96/rack, 10 racks/box); reload/refill formats are available for high-volume filter tip users.
<h2 dir="ltr"> Specifications Context</h2>
 Globe Scientific filter tips are certified free of human DNA, RNase, DNase, pyrogens, and PCR inhibitors; sterile, in flip-top or hinged racks. Sorenson Bioscience universal filter tips span 10&ndash;1,250 &micro;L in standard rack and EcoRack reload formats, pre-sterilised, DNase/RNase-free. Invitrogen Barrier Tips (Thermo Fisher) are the original reference for nucleic acid work with cellulose filter elements; compatible with Eppendorf pipettes. Globe Scientific, Nest Scientific, and Sorenson Bioscience filtered tips are stocked by MBP Inc.&nbsp; 
&nbsp;
Don&rsquo;t let cross-contamination stall your progress. <a href="https://mbpinc.net/contact-us" style="color: #236fa1;">Reach out to the MBP team</a> today for a quote or to find the perfect fit for your specific pipette brand.

<h2 dir="ltr"> What Are LTS-Compatible Filter Tips?</h2>
 LTS-compatible filter tips combine two design features: the cylindrical collar geometry of Rainin's LiteTouch System (LTS), which mates with Rainin LTS pipette shafts for low-insertion-force ergonomic operation, and an integrated hydrophobic aerosol-barrier filter element that prevents aerosol droplets and liquid from reaching the pipette barrel. They are the required tip format for Rainin LTS labs running PCR, qPCR, RT-PCR, RNA extraction, nucleic acid dispensing, or any contamination-sensitive workflow where both LTS ergonomics and aerosol protection are needed simultaneously. LTS filter tips are the single correct format for Rainin LTS users doing PCR, RNA, or biohazardous work &mdash; no substitution with universal filtered tips is possible. 
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" aria-level="1">
Diamond PosiStop Racked Tips &ndash; Precision-engineered for a perfect seal and easy, contamination-free loading.
</li>
<li dir="ltr" aria-level="1">
Bulk Packed Pipette Tips &ndash; High-volume, economical supply for routine laboratory liquid handling.
</li>
<li dir="ltr" aria-level="1">
Reload Stacks &ndash; Eco-friendly, space-saving inserts designed for rapid rack replenishment.
</li>
<li dir="ltr" aria-level="1">
GreenRack Systems &ndash; Sustainable, low-waste packaging for high-throughput diagnostic workflows.
</li>
<li dir="ltr" aria-level="1">
Sterile Rainin LTS Tips &ndash; RNase, DNase, and pyrogen-free options for sensitive molecular research.
</li>
<li dir="ltr" aria-level="1">
Empty Tip Racks &ndash; Durable, reusable frames designed for seamless use with reload components.
</li>
</ul>
<h2 dir="ltr"> How to Choose LTS-Compatible Filter Tips</h2>
 Confirm LTS Instrument Only pipettes displaying 'LTS' in the model designation &mdash; Pipet-Lite XLS+ LTS, Pipet-Lite M LTS, L8 LTS, L12 LTS &mdash; accept LTS tips. Standard Rainin models (older PIPET-LITE without 'LTS') and all non-Rainin pipettes require universal-fit tips, not LTS-specific tips. Low-Retention Filter Tips for Small Volumes Low-retention LTS filter tips combine the LTS mount, aerosol barrier, and hydrophobic inner wall. Use them when dispensing &le;20 &micro;L of RNA, enzyme, or protein solutions where maximum volume recovery plus contamination protection are simultaneously required &mdash; the most stringent tip specification for Rainin LTS users. Volume Range Common LTS filter tip volumes: 20 &micro;L, 200 &micro;L, 300 &micro;L, 1,000 &micro;L, and 1,200 &micro;L. Confirm the exact volume range available in LTS-compatible filter format from your supplier, as not all volumes are available in every format from every manufacturer. OEM vs Third-Party Rainin OEM filter tips for LTS are specified to the tightest cylindrical geometry tolerance. LTS filter tips are available in sterile racked and refill stacked-box formats with RNase/DNase/non-pyrogenic certification. For routine research use, third-party LTS filter tips offer equivalent performance at 20&ndash;40% lower cost. Packaging LTS filter tips are available in hinged racks (10 racks &times; 96 = 960 tips/box) and refill stacked-box inserts. Sterile options are standard across the range. 
<h2 dir="ltr"> Specifications Context</h2>
 LTS-compatible filter tips are manufactured from virgin polypropylene (PP) with hydrophobic PE filter frits; low-retention variants use hydrophobic resin for reduced surface adhesion.&nbsp;LTS filter tips: certified RNase-free, DNase-free, non-pyrogenic, CE and FDA-listed, in sterile refill stacked-box format. Multiple third-party manufacturers supply LTS-compatible filter tips at 20&ndash;40% below Rainin OEM pricing, with equivalent documented performance for research workflows.&nbsp; 
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<a href="https://mbpinc.net/contact-us" style="color: #236fa1;">Connect with the MBP team</a> today! Let&rsquo;s get you a quote for the tips that feel just as good as they perform.

LTS Compatible Filter Tips

Racked Filter Tips for Rainin LTS

Sterile racked filter tips (SKU: LTS) compatible with Rainin LTS pipettes, available in 20 µL, 200 µL, and 1000 µL volumes. E-beam sterilized, RNase/DNase/PCR inhibitor-free, hydrophobic aerosol filter included, 4,800 tips per case.

Tip Technology

Volumes Available

Filter

Sterilized

Pipette Tip Type

20ul Racked Filter Tips for Rainin LTS, 4800/Cs

200ul Racked Filter Tips for Rainin LTS, 4800/Cs

1000 Racked Filter Tips for Rainin LTS, 4800/Cs

Benchtop Recappers

<h2>What Are Benchtop Recappers?</h2>
&nbsp;
Benchtop recappers are compact, motor-driven instruments that automate the opening and sealing of screw-cap or push-cap sample storage tubes in standard rack formats (24-, 48-, and 96-position). They are used in biobanks, clinical sample management laboratories, genomics core facilities, and other environments where large numbers of cryogenic or ambient-storage tubes require repeated capping and decapping. Manual recapping at scale is a leading contributor to repetitive strain injury (RSI) in high-throughput sample preparation workflows.
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<h2>What you will find:</h2>
&nbsp;
<ul>
<li>RFID-enabled racks for reliable sample tracking</li>
<li>SBS-format compatibility for standardized laboratory workflows</li>
<li>Automated capper and decapper functionality for improved efficiency</li>
<li>Secure and consistent tube sealing with CT&trade; caps</li>
<li>Compact benchtop designs that maximize laboratory space</li>
</ul>
&nbsp;
<h2>How to Choose a Benchtop Recapper</h2>
&nbsp;
Throughput Format (24 / 48 / 96)
Select the rack format that matches your primary tube storage system. A 96-position automated device can process a full rack in under 60 seconds, while a semi-automated 8-channel row decapper can complete a single row in under 5 seconds, making it suitable for moderate-throughput laboratories without full-rack automation requirements.
Cap Type Compatibility
Confirm whether your tubes use screw caps or push caps, as each requires a different capping mechanism. Screw-cap recappers apply a preset torque value, typically between 1 and 5 N&middot;cm, and automatically stop when the proper seal is achieved. Push-cap systems rely on controlled vertical force. Multi-format adapters can support several tube brands within a single instrument.
Standalone vs. Integrated Systems
Standalone benchtop recappers are suitable for laboratories without dedicated automation infrastructure, while integrated models connect with Hamilton, Tecan, or Beckman Coulter workstations through SBS-format racks and software interfaces. Laboratories requiring LIMS connectivity and sample traceability should consider systems with built-in 1D and 2D barcode scanning capabilities.
Tube Diameter Range
Most automated recappers support standard collection tubes ranging from 13 to 16 mm in diameter and 75 to 115 mm in height. Verify compatibility with your cryovials or specialty microtubes before purchasing, particularly when using proprietary storage systems.
Maintenance Requirements
Pneumatics-free designs eliminate the need for compressed-air infrastructure and generally reduce maintenance demands. Pneumatic systems may offer high performance but require periodic servicing and access to a laboratory air supply.
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<h2>Specifications Context</h2>
&nbsp;
Rack format (24, 48, or 96 tubes) establishes the maximum throughput of a benchtop recapper. Torque settings must be compatible with the selected tube and cap combination, since excessive torque can crack caps while insufficient torque can lead to evaporation or contamination. SBS-format compliance ensures interoperability with industry-standard racks and automated workflows. As of 2026, many benchtop recappers incorporate IoT-enabled monitoring, barcode integration, and LIMS connectivity to improve sample traceability and reduce manual documentation requirements in high-throughput laboratories.
<a href="https://mbpinc.net/contact-us">Contact the expert team at Molecular Biology Products Inc. (MBP)</a> today to find the right benchtop recapper for your laboratory workflow.

BioBlue Series Compound Microscopes-TDS-EBB-4260

BioBlue Series Compound Microscopes-TDS-EBB-4253

BioBlue Series Compound Microscopes-TDS-EBB-4220-LCD

BioBlue Series Compound Microscopes-Choosing a Microscope Made Easy

Rack - Brochure

Racks with RFID Disks for CapTrack, 36 Places

456445 by Globe Scientific is a half-size, 36-place reinforced nylon tube rack (3×12 array, 13 mm max tube OD, 100×102×57 mm) pre-assembled with a unique RFID disk for the CapTrack™ CT1 and CT2 automated sample tracking systems. Fully autoclavable; rust-resistant; available in multiple colours. Contact MBP at customerservice@mbpinc.net for volume pricing and colour availability.

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Blue 

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Green

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Magenta

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Orange

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Red

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, White

Wireless Tube Rack with RFID for CapTrack CT1 and CT2 models - Half size, 13mm, 36 place, Yellow

United States

Texas

mbpinc