Brands

Hotplate & Stirrer

<h2>What Are Laboratory Hotplates and Stirrers?</h2>
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Laboratory hotplates are electrically heated work surfaces used to warm flasks, beakers, and vessels containing reagents, culture media, buffers, and reaction mixtures. Magnetic stirrers use a rotating magnetic field beneath the plate to spin a PTFE-coated stir bar inside the vessel, providing uniform mixing without mechanical contact. Combination hotplate-stirrer units integrate both functions in a single instrument and are the most common format in chemistry, biology, and pharmaceutical labs. Standalone magnetic stirrers (without heating) are used for room-temperature mixing, pH measurement, and buffer preparation. Applications include chemical synthesis and recrystallization, cell culture media preparation, buffer and reagent preparation, dissolution testing, enzyme assays, protein and nucleic acid precipitation, and polymer synthesis. Digital hotplate-stirrers with PID temperature control, external probe inputs for actual solution temperature monitoring, and PTFE-coated ceramic or aluminum plates are the standard in research-grade instruments. Choose a combination hotplate-stirrer for most bench chemistry and biology work; choose a standalone magnetic stirrer for room-temperature mixing where a heating element would be a contamination or safety risk.
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<h2 dir="ltr">What You Will Find:</h2>
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<ul>
<li dir="ltr" aria-level="1">
<a href="https://mbpinc.net/equipments/temperature-control-equipment/hotplate-and-stirrers/magnetic-stirrers" title="Magnetic Stirrers">Magnetic Stirrers</a> provide powerful, quiet rotation using high-quality magnetic bars to ensure your liquids are blended perfectly every time.
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<li dir="ltr" aria-level="1">
<a href="https://mbpinc.net/equipments/temperature-control-equipment/hotplate-and-stirrers/hotplate-and-stirrer-accessories" title="Hotplate &amp; Stirrer Accessories">Hotplate &amp; Stirrer Accessories</a> include everything from extra stir bars to external temperature probes, helping you customize your setup for better accuracy.
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<a href="https://mbpinc.net/equipments/temperature-control-equipment/hotplate-and-stirrers/multi-position-hotplate-stirrers" title="Multi-Position Hotplate Stirrers">Multi-Position Hotplate Stirrers</a> allow you to process several samples at once with uniform heat and speed, making your high-throughput days much more manageable.
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<a href="https://mbpinc.net/equipments/temperature-control-equipment/hotplate-and-stirrers/overhead-stirrers" title="Overhead Stirrers">Overhead Stirrers</a> deliver the high-torque power needed for thick, high-viscosity liquids that standard magnetic stirrers just can't handle.
</li>
</ul>
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<h2>How to Choose a Lab Hotplate or Stirrer</h2>
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Hotplate-only vs. stirrer-only vs. combination unit
Hotplates without a stirring function are used for applications requiring only controlled heating: drying samples, warming baths, or maintaining solution temperature without agitation. Standalone stirrers (no heating) handle room-temperature mixing, titrations, and sample homogenization without thermal risk. Combination hotplate-stirrers serve both purposes in one instrument and are the standard choice for chemistry and cell biology benches where both heating and mixing are regularly needed.
Plate material: ceramic vs. stainless steel vs. aluminum
Ceramic top plates resist corrosive chemical spills, provide a white surface ideal for titrations and colorimetric work, and withstand temperatures up to 550 degrees C. Stainless steel plates offer stronger magnetic coupling and higher stirring force, preferred for dense suspensions or high-viscosity liquids. Aluminum plates heat and cool faster than ceramic, making them suitable for applications requiring rapid temperature changes. PTFE-coated plates are chemically resistant but limited to lower temperatures.
Temperature range and accuracy
Standard combination units reach 300 degrees C to 380 degrees C on the plate surface. Digital PID-controlled units with an external temperature probe monitor actual solution temperature (not plate temperature) and maintain the solution within plus or minus 1 degree C at setpoint, which is important for temperature-sensitive enzyme reactions, crystallization protocols, and culture media preparation. Analog units without external probes rely on plate surface temperature, which can differ significantly from solution temperature.
Stirring speed and stir bar volume
Stirring speed ranges from 100 rpm for gentle mixing to 1500 rpm for vigorous suspension. Match stir bar size to vessel volume: a 10 mm bar for tubes and small vials, a 25 mm to 40 mm bar for 50 mL to 500 mL beakers, and a 50 mm to 80 mm bar for 1 L to 5 L vessels. Using a stir bar too large for the vessel prevents rotation; too small causes inefficient mixing.
Safety features
For work with flammable solvents, specify an explosion-proof or EX-rated hotplate with enclosed heating elements that do not produce sparks. Digital models with over-temperature alarms and contact temperature sensors on the plate surface prevent runaway heating events. Some models include motor auto-shutoff if the stir bar decouples, reducing the risk of unattended overheating.
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<h2>Specifications Context</h2>
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Maximum plate temperature (300 to 550 degrees C) is a surface rating; actual solution temperature depends on vessel geometry, fill volume, and heat loss. Use an external temperature probe (PT1000 or thermocouple) inserted into the solution for accurate setpoint control. Plate dimensions (typically 135 mm x 135 mm to 300 mm x 300 mm) determine the vessel sizes the unit can safely support; oversized vessels extending beyond the plate perimeter are unstable. PTFE stir bars should be inspected for wear periodically, as chipped PTFE releases particles into the solution; replace any stir bar showing surface damage.&nbsp;
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Ready to stir things up? Take a look through our hotplate and stirrer collection and <a href="https://mbpinc.net/contact-us">reach out to the MBP team</a> for a friendly quote today.

Hotplate & Stirrers

Flyer

GHS-380S - Product Guide

GHS-380H - Product Guide

Hotplate Stirrer

GHS-380 Group Hotplates & Stirrers

The GHS-380HS by Globe Scientific is a digital hotplate stirrer with a 380°C maximum temperature, 200–1,500 RPM stirring range, and a 140 × 140 mm (5.5 × 5.5 in) ceramic-coated aluminum plate. Rated at 510 W with IP21 protection, it operates on 100–120 V or 200–240 V and supports up to 5 L stir volume. Available from MBP Inc. for laboratory procurement across the USA and Canada.

Manufacture

Hotplate Stirrer, Digital, 380C Maximum Temperature, 5.5 x 5.5 inch ceramic coated top plate, 100-120v, 50-60Hz

Hotplate Stirrer, Digital, 380C Maximum Temperature, 5.5 x 5.5 

Hotplate, Digital, 380C Maximum Temperature, 5.5 x 5.5 inch ceramic coated top plate, 100-120v, 50-60Hz

Hotplate, Digital, 380C Maximum Temperature, 5.5 x 5.5 inch ceramic coated top plate, 200-240v 50-60Hz

Stirrer, Digital, 5.5 x 5.5 inch ceramic coated top plate, 100-240v, 50-60Hz

Hotplate-Stirrer

Sensor support stand and clamp, for use with GHS-550 models

Sensor support stand and clamp, small, for use with GHS-380 models

Temperature sensor, 230mm length, for use with GHS models with heat

Temperature sensor, 230mm length, glass coated, for use with GHS models with heat

GHS-550 Group Hotplates & Stirrers

GHS-550 by Globe Scientific — four-model group of digital hotplates, magnetic stirrers, and combination hotplate-stirrers with a 7 × 7 in glass ceramic surface and 550°C maximum. Stirrer models: 0–1500 rpm, brushless DC motor, up to 20 L (GHS-550HSP). GHS-550HSP adds PID control, LCD display, and RS232 port.

Hotplate Stirrer, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, with RS232 port, 100-120v, 50-60Hz

Hotplate Stirrer, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, with RS232 port, 200-240v 50-60Hz

Hotplate Stirrer, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, 100-120v, 50-60Hz

Hotplate Stirrer, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, 200-240v 50-60Hz

Hotplate, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, 100-120v, 50-60Hz

Hotplate, Digital, 550C Maximum Temperature, 7 x 7 inch glass ceramic  top plate, 200-240v 50-60Hz

Stirrer, Analog, 7 x 7 inch glass ceramic  top plate, 100-120v, 50-60Hz

Stirrer, Analog, 7 x 7 inch glass ceramic top plate, 200-240v 50-60Hz

Homogenizer Accessories

<h2>What are homogenizer accessories?</h2>
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Homogenizer accessories are the interchangeable tools, replacement parts, and supporting vessels and hardware that enable a laboratory homogenizer to be used across different sample volumes, sample types, and processing conditions beyond what the base instrument alone provides. For rotor-stator homogenizers, the critical accessories are the generator head and dispersing tool (the probe tip with rotating blade inside a stator tube), available in different sizes to match different sample volumes. For ultrasonic probe homogenizers, the primary accessories are the sonic probe tip or microtip, which is the consumable component that transmits ultrasonic energy and eventually wears or fatigues. Additional accessories include cleaning stations, jacketed vessels for temperature control, and support stands.
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<h2>What you will find:</h2>
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<ul>
<li>Rotor-stator homogenizer generator probes</li>
<li>Rotor-stator homogenizer probe tips and microtips</li>
<li>Bead kit and bead grinding media for bead mill homogenizers</li>
<li>Sample tube adapters and holders for homogenizers</li>
<li>Stands, clamp attachments, and supports</li>
<li>Cup horns and flow cells for ultrasonic homogenizers</li>
<li>Sound chamber enclosures for noisy ultrasonic homogenizers</li>
<li>Seals and other replaceable homogenizer parts </li>
</ul>
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<h2>How to choose homogenizer accessories</h2>
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Match the generator head size to your sample volume
Rotor-stator generator heads (dispersing elements) are designed for specific volume ranges: the S10N generator head suits 0.5&ndash;30 mL, S18N suits 5&ndash;150 mL, and S25N suits 50&ndash;500 mL volumes in common IKA Ultra-Turrax style instruments. Processing a 2 mL sample with a large S25N head gives poor energy density; processing 200 mL
Check ultrasonic probe tip diameter against the sample vessel and volume
Ultrasonic probe homogenizer tips are available in standard (12.7&ndash;19 mm) and micro (3&ndash;6 mm) diameters, with the micro-tip providing higher acoustic intensity for small volumes and the standard tip covering larger volumes. The tip diameter should be approximately 1/4 to 1/3 of the diameter of the sample container for effective cavitation throughout the sample.
Replace ultrasonic probe tips before pitting becomes severe
Ultrasonic probe tips erode at the vibrating face through cavitation, and a pitted tip delivers less energy, generates metal particles contaminating the sample, and risks mechanical failure. Inspect the tip face regularly for pitting and replace at the first signs of significant erosion to maintain energy delivery.
Use a water-jacketed vessel for temperature-sensitive samples
Water-jacketed homogenization vessels circulate cold water around the sample vessel during homogenization, limiting the temperature rise in the sample from frictional and ultrasonic heating. This is particularly important for enzyme preparations, RNA isolation, and other applications where sample heating above a few degrees above ambient can cause degradation.
Invest in a probe cleaning station for high-throughput work
Probe cleaning stations hold cleaning and rinse solutions in sequence for rapid cleaning between samples, reducing cleaning time and ensuring consistent decontamination in labs processing many samples per session compared with manual cleaning.
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<h2>Specifications context</h2>
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Ultrasonic probe tip replacement is a consumable cost, with tip lifespan typically 50&ndash;200 hours before pitting degrades performance. Manufacturers specify replacement tip models compatible with each horn assembly; non-specified tips risk poor energy coupling or damage. Titanium alloy probe tips remain the standard material for their combination of acoustic properties, corrosion resistance, and fatigue resistance under repeated ultrasonic cycling.
<a href="https://mbpinc.net/contact-us">Contact us to receive a quotation</a> on our homogenizer accessories from our expert staff at Molecular Biology Products Inc.

Gasket Accessories for IPD9600-25G

Benchmark Scientific IPD9600-25G: replacement gasket for the 25 mL stainless steel grinding jar (IPD9600-25S) used with the BeadBlaster 96 / IPD9600 grinding mill. Sold individually (1 gasket/unit). Maintains jar seal integrity during bead-based homogenization.

Gasket for Stainless steel 25ml jar, 25ml, each

Gasket for 50ml Stainless steel jar, each

Cryo Kit for liquid nitrogen

<h2>What are ball mills and mixing equipment?</h2>
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Ball mills and mixing equipment use mechanical energy to grind solid samples into fine particles, disrupt biological cells for molecular extraction, homogenize heterogeneous samples, and mix reagents, solvents, or cultures. The major types include planetary ball mills that use rotating grinding vessels with balls for high-energy size reduction; bead mill homogenizers that shake tubes containing sample and small beads for rapid cell disruption in molecular biology; vortex mixers for rapid agitation of tubes and microplates; rocker and roller platforms for gentle continuous mixing during incubation steps; and overhead stirrers for viscous or large-volume applications.
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<h2 dir="ltr">What you will get here:</h2>
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<ul>
<li dir="ltr" aria-level="1">
Laboratory ball mills for particle grinding
</li>
<li dir="ltr" aria-level="1">
Planetary ball mills for mixing
</li>
<li dir="ltr" aria-level="1">
Jar mills for grinding and blending
</li>
<li dir="ltr" aria-level="1">
Mixer mills for sample homogenizing
</li>
<li dir="ltr" aria-level="1">
Vibratory ball mills for small sample grinding
</li>
<li dir="ltr" aria-level="1">
Grinding jars and milling media
</li>
<li dir="ltr" aria-level="1">
Benchtop ball mills for labs
</li>
<li dir="ltr" aria-level="1">
High energy mills for research
</li>
</ul>
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<h2>How to navigate Ball Mills &amp; Mixing equipment</h2>
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Use a planetary ball mill or mixer mill for grinding hard materials to powder
Planetary ball mills and swing/mixer mills apply high-energy impact and friction to grind rock, minerals, soil, plant material, and other hard samples to micrometer-scale particle size in minutes, suitable for preparing samples for elemental analysis, spectroscopy, or other analytical methods requiring homogeneous fine powder.
Use a bead mill homogenizer for fast cell disruption and tissue homogenization
Bead mill homogenizers (such as the FastPrep, TissueLyser, or equivalent) shake or oscillate tubes filled with sample and small beads at high speed, lysing cells and disrupting tissue in seconds to a few minutes, producing a homogeneous lysate directly in the tube with no external probe to clean between samples.
Choose vortex mixers for rapid tube agitation in routine molecular biology
Vortex mixers provide rapid circular agitation of tubes by pressing the closed tube onto the vibrating cup surface, and are used throughout molecular biology for mixing reactions, resuspending pellets, mixing samples with buffers, and other quick agitation tasks where brief, high-intensity mixing is needed.
Use rocker or roller platforms for gentle long-duration mixing
Rocking platforms, rotating wheel mixers, and roller platforms provide gentle, continuous mixing suitable for antibody incubation on blot membranes, bead incubations for immunoprecipitation, and other applications where prolonged agitation rather than brief intense mixing is needed.
Consider throughput when selecting bead mill or mixing equipment
Single-tube bead mill homogenizers process one sample at a time for precious or highly variable samples, while 24-well or 96-well plate format bead mills process many samples simultaneously. Vortex mixers with microplate adaptors mix entire 96-well plates at once, suitable for high-throughput molecular biology workflows.
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<h2>Specifications context</h2>
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Bead mill homogenizers are characterized by oscillation speed, tube format support, and cooling adapter availability to prevent sample heating during extended bead beating. As of 2026, bead mill homogenizers with interchangeable adapters for 2 mL microtubes, 15/50 mL centrifuge tubes, and 96-well plates are the standard in core facility and high-throughput molecular biology settings.
<a href="https://mbpinc.net/equipments/ball-mills-and-mixing">Get a quote from MBP</a> &ndash; the experts in molecular biology products.

Ball Mills & Mixing

Gear-Drive Planetary Ball Mill Specifications

PQN04 Standard Package

PQN2 Standard Package

PQN4 Standard Package

Across International PQ-N 4x1000ml Gear-Drive 4-Liter Planetary Ball Mill

New! UL/CSA Certification for Ball Mills

Gear-Drive Planetary Ball Mill

Across International Gear-Drive Planetary Ball Mills available in 0.4 L (4×100 mL), 2 L (4×500 mL), and 4 L (4×1000 mL) configurations, grinding to 0.1 μm with programmable timers and CE certification. Compatible with 110 V or 220 V supply.

Manufacturer

4x100ml Gear-Drive 0.4L Planetary Ball Mill

4x500ml Gear-Drive 2-Liter Planetary Ball Mill

4x1000ml Gear-Drive 4-Liter Planetary Ball Mill

Electrophoresis System Accessories

User Manual

Product Literature

Accuris myGel Mini electrophoresis-MyGel Mini Comb

Gel Casting Stand for 5x6cm gels, includes 4 trays, and 2 combs (18/10 teeth)

E1101-CS2 by Accuris is the SureCast™ gel casting set for 5 × 6 cm mini gels, designed for the E1101 myGel™ Mini Electrophoresis System. The kit includes four 5 × 6 cm casting trays and two double-sided combs (18/10 teeth), enabling rapid small-format gel runs for colony PCR screening, restriction digest confirmation, and teaching workflows.

Gel Casting set for 10.5x6cm gels, includes stand, 2 trays, and 2 combs(22/12 teeth)

E1101-CS1 by Accuris Instruments is the myGel Mini gel casting set for 10.5 × 6 cm agarose gels, including a casting stand, 2 trays, and 2 reversible combs (22-tooth and 12-tooth faces) for the Accuris E1101 electrophoresis system.

<h2>What are Gel Extraction Kits?</h2>
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Gel extraction kits (gel purification or gel DNA recovery kits) isolate specific DNA fragments from standard and low-melting agarose gels after electrophoresis by dissolving the excised gel band in a chaotropic buffer that melts agarose and conditions DNA to bind a Zymo-Spin followed by washing to remove agarose, gel stains (EtBr, SYBR Safe, GelRed), salts, and proteins, and elution in 30-50 ul. Gel extraction is the primary method for isolating specific DNA fragments from multi-band reactions - PCR amplifications producing non-specific products, restriction digests generating multiple fragments, and vector preparations requiring removal of small insert-incompatible fragments. Use gel extraction instead of direct PCR cleanup whenever the reaction produces more than one visible band and only a specific size is needed downstream; for single-band reactions, PCR cleanup recovers 10-20% more DNA in the same protocol time.
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<h2 dir="ltr">What you will find:</h2>
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<ul>
<li dir="ltr" aria-level="1">
Zymoclean&trade; Gel DNA &amp; RNA Recovery: Innovative spin-column systems created for quick extraction of nucleic acids without any salt or agarose contamination.
</li>
<li dir="ltr" aria-level="1">
ZR small-RNA&trade; PAGE Recovery: A dedicated method for the accurate isolation of microRNA and small RNA types from polyacrylamide gels, preserving isoform uniqueness.
</li>
<li dir="ltr" aria-level="1">
Large Fragment DNA Recovery: Designed methods for the careful elution of high-molecular-weight DNA, avoiding mechanical shearing for extended-read sequencing.
</li>
<li dir="ltr" aria-level="1">
High-Throughput &amp; Universal Kits: Adaptable ZR-96 formats and flexible Column-Pure systems designed for standard laboratory cleanup and automated processes.
</li>
</ul>
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<h2>How to Choose a Gel Extraction Kit</h2>
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Fragment Size Range
Standard silica-column gel extraction kits ( Zymo Zymoclean, Thermo Fisher GeneJET) purify 70 bp to 10 kb with &gt;80% recovery for 200 bp-5 kb.&nbsp; For fragments larger than 10 kb requiring size-selective gel purification, use electroelution, agarase digestion of low-melting agarose, or pulse-field gel extraction followed by alcohol precipitation.
Agarose Percentage and Dissolution Protocol
For standard 0.8-2% agarose gels: use 3 volumes of dissolution buffer per 1 volume (weight:volume) of gel slice at 50-60 degrees C for 5-10 minutes. For high-percentage gels (&gt;2%): use 6 volumes of dissolution buffer and extend incubation to 10-15 minutes, or add isopropanol to help dissolve the denser agarose matrix. Incomplete dissolution is the most common cause of low yield and must be verified visually - no visible agarose particles should remain in the dissolved solution before loading the column.
Elution Volume
For cloning applications where insert concentration matters, use the minimum elution volume (30-35 ul) to maximize insert concentration for ligation. For sequencing of gel-purified products, elute in 30-50 ul and measure concentration by Qubit or NanoDrop before use.&nbsp;
UV Exposure Minimization
UV transilluminator exposure damages DNA via pyrimidine dimer formation, reducing downstream PCR amplification and sequencing efficiency. Limit UV exposure to &lt;30 seconds when excising bands; use a long-wavelength (365 nm) UV source instead of short-wavelength (254 nm) to minimize damage. Alternatively, use a blue-light transilluminator (Safe-Imager, Clare Chemical DarkReader) with SYBR Safe or GelRed stain, which causes no photodamage to DNA during band excision.
Column vs. Magnetic Bead Gel Extraction
Standard gel extraction uses spin columns. For 96-well high-throughput gel extraction applications, vacuum-manifold compatible 96-well plate formats (Norgen DNA Gel Extraction Kit 96-well) process multiple samples simultaneously. AMPure XP magnetic beads can perform gel-alternative size selection from solution without the gel step, which avoids UV damage entirely and is preferred in NGS library preparation workflows where fragment size distribution rather than specific band isolation is the goal.
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<h2>Specifications Context</h2>
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Key benchmarks for gel extraction kits: &gt;=70% recovery for 200 bp-5 kb fragments from 1% TAE agarose gels, A260/A280 &gt;= 1.7 in eluate, no detectable agarose (confirmed by no viscosity increase in eluate), and complete removal of gel stain and EtBr (confirmed by absence of stain fluorescence in eluate). The Zymo Zymoclean Gel DNA Recovery Kit purifies DNA from TAE or TBE gels using Zymo-Spin technology, eluting in as little as 6 ul for highly concentrated DNA in minutes. Gel extraction remains an essential cloning technique at academic molecular biology labs, with blue-light transilluminator-based band excision increasingly replacing UV-based methods to protect DNA integrity during size selection.
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Unleash the genetic capabilities of your samples&mdash;<a href="https://mbpinc.net/contact-us">reach out to MBP Inc.</a> now to obtain a quote for our gel recovery services.

Gel Extraction Kits

Gel Extraction Kit

Gel Extraction Kit (DC3511-00) by MBP recovers DNA from agarose gels and purifies DNA fragments from PCR, RFLP, and other enzymatic reactions. 70 bp to 20 kb using ezBind™ mini column; over 80–90% recovery. Available in 4 (DC3511-00), 50 (DC3511-01), and 250 (DC3511-02) prep sizes.

Gel Extraction Kit , 4 Preps

Gel Extraction Kit , 50 Preps

Gel Extraction Kit , 250 Preps

<h2 data-section-id="3d1466" data-start="0" data-end="47">What are cell culture buffers and solutions?</h2>
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Cell culture buffers and balanced salt solutions are isotonic solutions used to wash, dilute, transport, and temporarily maintain cells outside of complete growth media. Unlike culture media, these solutions do not contain the nutrients and growth factors required for cell proliferation. Instead, their primary role is to maintain physiological pH and osmotic balance while protecting cells from stress during handling and experimental procedures.
The most commonly used cell culture buffers include PBS (Phosphate-Buffered Saline), DPBS (Dulbecco's Phosphate-Buffered Saline), HBSS (Hank's Balanced Salt Solution), and EBSS (Earle's Balanced Salt Solution). These solutions are widely used in cell washing, passaging, tissue dissociation, sample preparation, immunoassays, and short-term cell maintenance.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Standard Isotonic Buffers to wash cells, maintain osmotic balance, and dilute reagents.</li>
<li dir="ltr" role="presentation">Biological Buffering Agents for metabolic support and pH maintenance.</li>
<li dir="ltr" role="presentation">Cell Dissociation &amp; Neutralizing Reagents maintain high cell viability and are used for cell recovery, detachment, and passaging</li>
<li dir="ltr" role="presentation">Surface Coating &amp; Matrix Solutions with high-grade gelatin for improved cell attachment.</li>
<li dir="ltr" role="presentation">Insulin-Transferrin-Selenite (ITS), Bovine Serum Albumin (BSA), and high-purity Holo-Transferrin for enhanced cell growth and viability</li>
</ul>
&nbsp;
<h2 data-section-id="1cuz7jf" data-start="1165" data-end="1216">How to choose cell culture buffers and solutions</h2>
&nbsp;
PBS vs. DPBS PBS is a simple sodium chloride/phosphate buffer solution. DPBS adds potassium chloride and may include calcium, magnesium, glucose, and pyruvate depending on formulation. The practical difference between PBS and DPBS formulations is minimal &mdash; both maintain pH 7.2-7.4 and osmolality ~280-315 mOsm/kg and are functionally interchangeable for standard washing, immunoassay, and sample preparation applications. If your protocol is sensitive to minor salt concentration differences, compare specific formulation sheets rather than assuming equivalence. &nbsp; Calcium/magnesium-free vs. calcium/magnesium-containing Calcium and magnesium facilitate cell-cell and cell-surface adhesion. Calcium/magnesium-free PBS, DPBS, or HBSS is required: before enzymatic dissociation (residual Ca/Mg inhibits trypsin, requiring more enzyme and harsher conditions &mdash; the most common cause of poor trypsinization results), for rinsing EDTA or other chelators from culture, and for minimizing cell-cell aggregation during gentle dissociation or suspension recovery. Calcium/magnesium-containing formulations support cell binding and clumping, useful for transport applications or attachment-dependent procedures. &nbsp; HBSS/EBSS vs. PBS/DPBS for short-term maintenance HBSS and EBSS include sodium bicarbonate buffering and may include glucose, providing meaningfully better short-term physiological support for cells &mdash; particularly under CO₂ atmosphere &mdash; than the simpler PBS/DPBS formulations. Use HBSS/EBSS when cells need to remain viable for a meaningful period outside complete growth media (tissue dissociation workflows, transport, short-term holding). Use PBS/DPBS for washing steps, immunoassay/Western blot dilutions, and sample preparation where osmotic balance &mdash; not metabolic support &mdash; is the requirement. &nbsp; Phenol red and glucose/pyruvate variants DPBS and HBSS are available with or without phenol red and with or without glucose/pyruvate, allowing matching to downstream applications (phenol red-free for fluorescence work; glucose/pyruvate-containing for short-term metabolic support). &nbsp; Endotoxin and quality testing Regular quality testing of balanced salt solutions includes osmolality, pH, stability, and screening for endotoxins and bacterial/fungal contamination. For immune cell handling and other endotoxin-sensitive applications, premium formulations document endotoxin levels below 0.005 EU/mL &mdash; a meaningfully tighter specification than standard research-grade buffers. &nbsp; Powder vs. liquid format Powdered balanced salt solutions are manufactured without sodium (to avoid sodium bicarbonate off-gassing during storage), requiring sodium bicarbonate addition, pH adjustment, and sterile filtration at time of preparation &mdash; following the same principle as powdered classic media.Specifications context
&nbsp;
<h2>Specifications context</h2>
&nbsp;
Most balanced salt solutions are formulated to maintain physiological conditions with a pH of approximately 7.2&ndash;7.4 and osmolality ranging from about 280&ndash;315 mOsm/kg. These properties help minimize osmotic stress and maintain cell viability during handling.
Calcium- and magnesium-free DPBS remains one of the most commonly specified buffers for cell dissociation workflows because it improves the effectiveness of trypsin and other detachment enzymes. HBSS and EBSS continue to be widely used when short-term metabolic support is required outside complete growth media.
<a href="https://mbpinc.net/contact-us">Contact the expert team</a> at MBP today to get high-purity buffers and solutions for your lab.

Buffers & Solutions

Buffers/Salts

Gelatin Coating Solution (0.1%)

Gelatin Coating Solution 0.1% (TM063) by Applied Biological Materials is a 100 ml sterile collagen-derived gelatin solution for coating tissue culture surfaces to improve cell attachment, validated for mESC, miPSC, and PEF culture. Do not freeze. Store at 2–8°C; stable 12 months from shipment.

Unit Quantity

Sterility

Appearance

Storage Condition

Disclaimer

Shipping Condition

PCR & qPCR Film

DataSheet

General Application (PCR and Storage) Sealing Films

SF-AS-400 General Application Sealing Films by Novasbio are adhesive plate seals for standard PCR and storage, available in pierceable aluminium (SF-AS-400), polyester PCR/storage (SF-TS-600, −20°C to +120°C), and storage-only polyester (SF-TS-200) formats. All are DNase/RNase/human-DNA-free. Available from MBP Inc.

Packaging

LT Storage Aluminum sealing film for Long Term Storage. Pierceable. 100/PK 5PK/CS

PCR, Storage General application sealing film for PCR and Storage 100/PK 5PK/CS

Storage General application sealing film for Storage 100/PK 5PK/CS

Funnels

<h2>What Are Laboratory Weighing Funnels?</h2>
&nbsp;
Laboratory weighing funnels are single-use antistatic polypropylene (PP) funnels specifically designed for the weighing-and-transfer step in analytical chemistry, pharmaceutical weighing, and sample preparation workflows. Unlike standard powder funnels, weighing funnels have one flat side that allows the funnel to rest stable on a balance pan during mass measurement, and a conical stem sized to the neck of a specific volumetric flask volume. After the sample mass is recorded, the funnel inserts directly into the flask neck, and the sample is transferred by tipping or rinsing&mdash;providing quantitative, loss-free transfer into narrow-neck vessels. Available in extra small (fits microtubes and 5&ndash;20 mL flasks) through extra-extra-large (fits 1000 mL+ vessels). Antistatic weighing funnels are single-use; washing removes the antistatic treatment. Reusable funnels needing autoclave sterilization should be standard polypropylene powder funnels, not antistatic weighing funnels.
&nbsp;
<h2>What you will find:</h2>
&nbsp;
<ul>
<li>Powder funnels with wide stems for smooth solid transfer</li>
<li>Long-stem funnels for controlled pouring into narrow containers</li>
<li>Short-stem funnels for faster liquid transfer</li>
<li>Filter funnels for use with standard filter paper</li>
<li>Chemical-resistant plastic funnels for lab compatibility</li>
<li>Disposable funnels for single-use workflows</li>
</ul>
&nbsp;
<h2>How to Choose Laboratory Weighing Funnels</h2>
&nbsp;
Match Size to Flask Neck
The critical specification for a weighing funnel is the stem outer diameter relative to the flask neck inner diameter. Extra small fits 96-well microtubes and 5&ndash;20 mL volumetric flasks; small fits 20&ndash;50 mL; medium fits 50&ndash;200 mL; large fits 200&ndash;500 mL; extra large fits 500&ndash;1000 mL. A funnel that is too wide will not insert and will spill during transfer&mdash;when in doubt, choose one size smaller.
Disposable Antistatic vs. Reusable PP
For analytical weighing of fine powders, use disposable antistatic PP funnels&mdash;the antistatic surface dissipates charge that causes powder adhesion. For bulk transfer of coarse materials or liquids where static is not an issue, standard reusable polypropylene powder funnels (autoclavable at 121&deg;C, large-bore stem) are more economical and can be sterilized between uses.
Assorted vs. Individual Packs
Assorted packs covering extra small through extra large provide flexibility when flask sizes vary across experiments and reduce the number of individual SKUs to manage. Individual packs are more economical when only one funnel size is used at high volume.
Flat-Side Stability
All antistatic weighing funnels have one flat side on the funnel body. This flat face allows the funnel to rest stably on a balance pan without rolling during the weighing step before transfer&mdash;a design feature absent on standard laboratory funnels.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
Antistatic polypropylene weighing funnels achieve antistatic performance through a surface additive incorporated during molding; this is a surface treatment rather than a bulk polymer property. The flat side is designed to rest on a balance pan while keeping the stem vertical for direct transfer into volumetric flasks. As of 2026, these funnels are standard in pharmaceutical QC and analytical chemistry labs for gravimetric transfer workflows compliant with USP procedures. Explore weighing dishes and funnels category for related consumables.
Pick the size that fits your work&mdash;and everything else gets a lot easier.&nbsp;<a href="https://mbpinc.net/consumables/tubes-and-sample-collection/funnels" title="Contact the MBP Team">Contact the MBP Team</a> today.

General Purpose Funnels Specifications

General Purpose Funnel, HDPE

Globe Scientific 604171 general-purpose HDPE funnel, 80 mm top I.D., 100 mL capacity, 13 mm OD × 27 mm stem. External ribbing prevents air lock during liquid transfer. Sold 5/bag.

Funnel, General Purpose, HDPE, 80mm, 100mL, BAG/5

Funnel, General Purpose, HDPE, 100mm, 300mL, BAG/5

Funnel, General Purpose, HDPE, 120mm, 450mL, BAG/5

Funnel, General Purpose, HDPE, 140mm, 750mL, BAG/5

Funnel, General Purpose, HDPE, 180mm, 1500mL, BAG/5

Funnel, General Purpose, HDPE, 220mm, 2750mL, BAG/5

Funnel, General Purpose, HDPE, 250mm, 4000mL, BAG/5

Funnel, General Purpose, HDPE, 300mm, 5500mL, BAG/5

Funnel, General Purpose, HDPE, 420mm, 10000mL, BAG/5

<h2 data-section-id="1go10h8" data-start="173" data-end="215">What are classic cell culture media?</h2>
&nbsp;
Classic cell culture media refers to the foundational basal medium formulations that have underpinned mammalian cell culture since the mid-20th century: DMEM (Dulbecco's Modified Eagle Medium), MEM (Minimum Essential Medium), RPMI 1640, Ham's Nutrient Mixtures F-10 and F-12, IMDM (Iscove's Modified Dulbecco's Medium), and the combination formulation DMEM/F-12. Each is manufactured according to its originally published formula, with modifications limited to those necessary for consistent performance and stability of the medium over its shelf life. These media supply the amino acids, vitamins, glucose, salts, and (in most formulations) phenol red pH indicator that form the nutritional backbone of essentially all subsequent specialty, serum-free, and Advanced media derivatives.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Selective Mammalian Antibiotics including Puromycin, Geneticin, and Hygromycin B for stable development of cell lines.</li>
<li dir="ltr" role="presentation">Broad-Spectrum Bactericidal Agents for routine contamination prevention, including Penicillin/Streptomycin and Gentamicin&nbsp;</li>
<li dir="ltr" role="presentation">Prokaryotic Selection Reagents for effective bacterial transformation, including Ampicillin, Kanamycin, Chloramphenicol, and Tetracycline&nbsp;</li>
<li dir="ltr" role="presentation">Antifungal and Antimycotic Solutions to maintain sterile cultures, including combined 100X cocktails and Amphotericin B (Fungizone)&nbsp;</li>
<li dir="ltr" role="presentation">Specialized Small Molecules for targeted biochemical assays, including Ganciclovir, Rapamycin, and Actinomycin D&nbsp;</li>
</ul>
&nbsp;
<h2 data-section-id="1mfajxk" data-start="1218" data-end="1252">How to choose a classic medium</h2>
&nbsp;
DMEM vs MEM
DMEM contains up to four times the amino acid and vitamin concentration of original Eagle's MEM, along with higher glucose levels, making it suitable for cell types with elevated nutrient demands &mdash; DMEM is broadly applicable across mammalian, insect, and plant cell phenotypes including primary cells, stem cells, and transformed lines. MEM remains widely used for monolayer culture of many standard cell types, with optional Hanks' or Earle's salt formulations and a calcium-free modification that permits suspension growth.
RPMI 1640 for suspension and hematopoietic culture
RPMI 1640, developed at the Roswell Park Memorial Institute for culturing human leukemic cells, is optimized for non-adherent cell types &mdash; lymphocytes and other blood cells &mdash; and contains glutathione plus higher biotin, B12, and PABA concentrations than DMEM or MEM. Despite its hematopoietic origin, RPMI 1640 supports a broad range of adherent lines (HeLa, T47D, RENCA, CT26.WT) when properly supplemented.
Ham's F-10/F-12 for CHO and specialized applications
Ham's nutrient mixtures were originally developed for CHO cell clones, HeLa cells, and mouse L-cells, and remain suited to hepatocyte culture, viral fusion experiments, and toxicity assays, with formulations available for use with or without serum. Coon's modification of Ham's F-12 roughly doubles the amino acid and pyruvate content and adds ascorbic acid, developed specifically for hybrid cells produced by viral fusion.
DMEM/F-12 for complex, rich-medium applications
DMEM/F-12 (1:1 mixture) combines DMEM's glucose, amino acid, and vitamin richness with Ham's F-12's zinc, putrescine, hypoxanthine, and thymidine, producing an extremely rich complex medium used for MDCK cells, glial cells, fibroblasts, and human endothelial cells &mdash; and serving as the basal medium for many serum-free Advanced formulations used in organoid and stem cell work.
IMDM for high-density rapid proliferation
IMDM further enriches DMEM with additional amino acids and vitamins, substituting potassium nitrate for ferric nitrate and adding HEPES and sodium pyruvate. IMDM's sodium bicarbonate buffer system (5&ndash;10% CO₂) and enriched composition make it well suited for rapidly proliferating, high-density cultures including Jurkat, COS-7, and macrophage cells.
Liquid vs. powder format
Liquid classic media are ready to use (after appropriate FBS and supplement addition) and include sodium bicarbonate in the formulation. Powdered media are manufactured without sodium bicarbonate, since it tends to off-gas in powder form &mdash; 3.7 g/L sodium bicarbonate must be added upon reconstitution, followed by sterile filtration. Powder formats offer cost and shipping-weight advantages for high-volume labs preparing their own media.
&nbsp;
<h2 data-section-id="17i0pj" data-start="5035" data-end="5061">Specifications context</h2>
&nbsp;
Classic media are manufactured according to originally published formulas, with stability-related modifications documented per product. DMEM's sodium bicarbonate buffer system at 3.7 g/L is standard across liquid formulations; powdered formats require this addition upon reconstitution along with 0.22 &micro;m sterile filtration. As of 2026, DMEM, DMEM/F-12, and RPMI 1640 remain the three most widely specified classic media across academic and biomanufacturing labs, with IMDM increasingly used for high-density suspension applications in bioprocessing.
For recombinant growth factors and cytokines used alongside classic media, see Recombinant Proteins. For supplementation reagents (GlutaMAX, NEAA, sodium pyruvate, HEPES), see Cell Culture Supplements &amp; Additives. Browse Mammalian Cell Culture for the broader category.
<a href="https://mbpinc.net/contact-us">Contact the expert team </a>at MBP to get highly efficient microbial control solutions for your lab.

Antibiotics

Geneticin (Antibiotic G418)

Geneticin (Antibiotic G418) G271 by ABM — 50 mg/mL active G418, 0.2 µm filtered, sterility tested, 10 mL liquid. Selects for neomycin-resistant transfected cells at 400 µg/mL. Ships from MBP INC to USA, Canada, and international labs.

Usage

<h2>What are DNA Cleanup Kits?</h2>
&nbsp;
DNA cleanup kits purify and concentrate pre-extracted or pre-amplified DNA by removing enzymes, salts, organic solvents (phenol, chloroform), unincorporated nucleotides, RNA, detergents, and other contaminants from DNA solutions using silica-membrane spin columns with a bind-wash-elute protocol. Unlike PCR cleanup kits that are specifically optimized to remove primers and dNTPs from PCR reactions, DNA cleanup kits accept broader input chemistries - including post-phenol-chloroform extraction DNA, genomic DNA in high-salt lysis buffers, restriction digest reactions, and dilute DNA solutions requiring concentration - and elute DNA in minimal volumes (as little as 6 ul) for immediate use in downstream applications. Use a DNA cleanup kit whenever your DNA preparation contains inhibitors incompatible with downstream enzymatic reactions, when residual phenol must be removed, or when dilute DNA must be concentrated into a small volume.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" aria-level="1">
DNA Clean &amp; Concentrator&trade; (DCC): Efficient spin-column systems (5, 25, 100, 500 preps) created to concentrate low-concentration DNA into ultra-pure, transfection-quality volumes.
</li>
<li dir="ltr" aria-level="1">
Genomic DNA Clean &amp; Concentrator: Tailored procedures for extracting large templates while maintaining genomic integrity for long-read sequencing uses.
</li>
<li dir="ltr" aria-level="1">
Select-a-Size DNA Clean &amp; Concentrator&trade;: Tailored systems for the recovery of size-specific fragments, efficiently eliminating adapter dimers and non-target amplicons.
</li>
<li dir="ltr" aria-level="1">
ZR-96 DNA Cleanup Systems: Scalable 96-well and MagBead configurations designed for high-throughput, automated processes while ensuring reproducibility-validated outcomes.
</li>
</ul>
&nbsp;
<h2>How to Choose a DNA Cleanup Kit</h2>
&nbsp;
Capacity and Input Volume
Zymo DNA Clean &amp; Concentrator kits are available in formats matched to DNA input mass: DCC-5 (&lt;=5 ug input, elute &gt;=6 ul), DCC-25 (&lt;=25 ug input, elute &gt;=25 ul), DCC-100 (&lt;=100 ug input, elute &gt;=25 ul). Choose the format whose maximum capacity exceeds your expected DNA input by at least 2-fold to avoid column overloading, which reduces yield and purity. For genomic DNA preparations from tissue (typically 5-30 ug), DCC-25 or DCC-100 is appropriate.
Minimum Elution Volume and Concentration
For maximum DNA concentration, Zymo DCC-5 elutes in 6 ul - the industry minimum for standard silica columns. If the input volume is 500 ul (1 ng/ul) and the elution is 6 ul, the final concentration reaches approximately 80 ng/ul (assuming 95% recovery), a concentration suitable for transfection, electroporation, and microinjection.
Size Selectivity
Standard DNA cleanup kits retain all DNA &gt;=100 bp. If size selection is also required, use gel extraction (for specific band isolation) or AMPure XP beads (for size-range selection by bead: volume ratio adjustment) rather than a standard cleanup kit.
Post-Phenol-Chloroform Cleanup
For DNA recovered from phenol-chloroform extraction, add 5 volumes of binding buffer and 2 volumes of 100% ethanol to the aqueous phase before column loading. The organic solvent in residual phenol or chloroform does not significantly impair column binding at these dilutions. Multiple column reloads allow processing of large aqueous-phase volumes through a single column.
RNase A Treatment for DNA-Only Preparations
For gDNA preparations that must be RNA-free for optical mapping or certain long-read sequencing library kits, add RNase A (100 ug/ml) to the DNA solution, incubate at 37 degrees C for 10 minutes, then proceed directly to DCC cleanup. The RNase digestion products are removed during the wash steps.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
Zymo DNA Clean &amp; Concentrator kits use a single-buffer system with Zymo-Spin column technology and recover DNA from PCR, enzymatic reactions, phenol-chloroform extractions, and dilute solutions. DNA is eluted in volumes as small as 6 ul, providing up to 80-fold concentration from 500 ul inputs. The kits remove enzymes, proteins, salts, organic solvents, dyes, unincorporated nucleotides, primers, and other small molecules, delivering DNA ready for restriction digestion, ligation, sequencing, Southern blotting, transfection, and long-read library preparation. DNA cleanup and concentration are standard workflow steps in genomics laboratories at Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center, where removing trace inhibitors from gDNA before library preparation significantly improves NGS library complexity and uniformity.
&nbsp;
Enhance your capabilities&mdash;<a href="https://mbpinc.net/contact-us">reach out to the MBP Inc. team</a> now to obtain a quote for your DNA concentration requirements.

DNA Cleanup Kits

D4064-MSDS

D4064-Protocol

Genomic DNA Clean & Concentrator™ Kit-25

D4064 by Zymo Research — Genomic DNA Clean &amp; Concentrator™-25 Kit (25 preps). Purifies and concentrates up to 25 µg high molecular weight DNA (50 bp to 200 kb) from enzymatic reactions and dilute samples in ~5 minutes. Elution ≥ 35 µl; recovery 70–95%; A260/A280 &gt; 1.8. Also available as D4065 (100 preps).