Genomic DNA

<h2>What Are Genomic DNA Extraction Kits?</h2>
&nbsp;
Genomic DNA extraction kits isolate chromosomal DNA from a wide range of starting materials, including whole blood, cultured cells, solid tissue, bacteria, and yeast, through lysis, binding to a silica membrane or magnetic beads under chaotropic salt conditions, washing, and elution. Standard kits typically yield DNA suitable for PCR, qPCR, restriction enzyme digestion, and routine sequencing applications, while specialized high-molecular-weight (HMW) kits target larger, less fragmented DNA for long-read sequencing workflows.&nbsp;A standard silica spin-column genomic DNA kit covers most PCR, qPCR, genotyping, and routine sequencing applications. Consider a high-molecular-weight DNA extraction kit when your workflow requires minimally fragmented DNA for long-read sequencing or structural variation analysis.
&nbsp;
<h2>What You Will Find</h2>
&nbsp;
<ul>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/viral">Viral Genomic DNA</a>: For sensitive monitoring of viral load, pathogen profiling, and molecular surveillance assays using optimized viral formulations.</li>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/blood/tissue">Blood/Tissue Genomic DNA</a>: High-molecular-weight genomic DNA extraction from mammalian blood and tissue samples for downstream sequencing applications.</li>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/plant">Plant Genomic DNA</a>: High-purity DNA extraction from plant samples with effective removal of common contaminants.</li>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/ffpe">FFPE Genomic DNA</a>: Rapid isolation of high-quality genomic DNA from formalin-fixed, paraffin-embedded tissue samples.</li>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/urine">Urine Genomic DNA</a>: Purification of cell-free and cellular DNA from urine samples for oncology, biomarker, and clinical research applications.</li>
<li><a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/insect">Insect Genomic DNA</a>: High-yield genomic DNA extraction from entomological samples.</li>
</ul>
<h2>&nbsp;</h2>
<h2>How to Choose a Genomic DNA Extraction Kit</h2>
&nbsp;
Starting Material Lysis
Different sample types require different lysis approaches. Blood cells generally lyse readily, while solid tissue often benefits from Proteinase K digestion to ensure complete cellular disruption. Bacteria and yeast may require enzymatic or mechanical cell-wall disruption before standard lysis buffers can effectively release genomic DNA.
Sample Volume and Yield Expectations
DNA yield is closely linked to starting material quantity and quality. Small volumes of fresh whole blood commonly produce several micrograms of genomic DNA using standard silica spin-column workflows, although exact yields vary by kit design, sample condition, and extraction method.
Fragment Size and DNA Integrity
Standard genomic DNA extraction kits are optimized for PCR, qPCR, and routine sequencing applications and typically recover DNA fragments under 30-50 kb. High-molecular-weight extraction kits use gentler lysis and purification chemistries to preserve longer DNA fragments, often exceeding 50 kb, making them well-suited to long-read sequencing technologies.
RNA Removal and Purity
Many genomic DNA extraction kits incorporate RNase A treatment to remove RNA contamination. This helps improve nucleic acid purity and can be particularly important for downstream applications that are sensitive to RNA carryover, including certain sequencing and library preparation workflows.
Sample Age and Storage History
DNA yield and integrity may be influenced by sample storage conditions and age. Fresh samples generally provide the highest-quality DNA, while archived or shipped specimens may exhibit some degree of DNA degradation or reduced yield that should be considered during experimental planning.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
Standard genomic DNA extraction kits rely on silica spin-column or magnetic bead-based purification workflows. Following cell or tissue lysis, genomic DNA binds to the purification matrix under chaotropic salt conditions while proteins, inhibitors, and other contaminants are removed during wash steps before final elution in water or low-salt buffer.&nbsp;These workflows generate DNA suitable for PCR, qPCR, restriction digestion, genotyping, and routine sequencing applications. RNase A treatment is commonly included to minimize residual RNA contamination and improve overall nucleic acid purity.&nbsp;High-molecular-weight genomic DNA extraction kits use gentler lysis and purification methods, including specialized magnetic bead or glass bead-based workflows, to minimize DNA shearing. These approaches can preserve DNA fragments exceeding 50-70 kb and are commonly selected for long-read sequencing platforms where fragment length directly influences read length and assembly quality.&nbsp;Genomic DNA extraction kit buffers are typically stable at room temperature, while enzyme components may require refrigeration or freezing. Lot-specific Certificates of Analysis (CoAs) are available on request.
&nbsp;
Need a bulk quote? Use MBP's <a href="https://mbpinc.net/quickorder">Quick Order</a> or <a href="https://mbpinc.net/contact-us">Contact Us</a> for volume pricing.

MSDS

Protocol

Pinpoint™ Slide DNA Isolation System

C1011-ZYM by Zymo Research — capped silica spin columns for purification of DNA (up to 25 µg) and RNA (up to 50 µg) in ≥ 25 µl eluate. 900 µl volumetric capacity; compatible with microcentrifuge and vacuum manifold. Available in 50-column and 250-column packs. Contact MBP for pricing and availability.

Applicable For

Equipment

Sample Source

Sample Storage

Size Range

Type

Enzyme Commission Number

pH and Temperature Range

Source (Proteinase K)

Specific Activity (Proteinase K)

Unit Definition (Proteinase K)

Manufacturer

Pinpoint™ Slide DNA Isolation System (50 Preps.)

Pinpoint Solution (1 ml)

Proteinase K w/ Storage Buffer Set (125 mg)

Proteinase K w/ Storage Buffer Set (20 mg)

Proteinase K w/ Storage Buffer Set (5 mg)

Proteinase K w/ Storage Buffer Set (60 mg)

Pinpoint Extraction Buffer (2.5 ml)

Pinpoint Binding Buffer (6 ml)

Pinpoint Wash Buffer (Concentrate) (2.4 ml)

<h2>What Are 96-Well Plate Genomic DNA Kits for Blood and Tissue?</h2>
&nbsp;
96-well plate genomic DNA kits for blood and tissue replace individual spin columns with silica-binding or glass-fiber plates that enable simultaneous purification of genomic, mitochondrial, or pathogen DNA from up to 96 samples per run. These systems are designed for whole blood, serum, plasma, lymphocytes, cultured cells, and selected tissue samples, providing efficient high-throughput DNA extraction for research and molecular testing workflows.&nbsp;Choose a 96-well plate genomic DNA kit when sample volumes justify batch processing on a plate-compatible centrifuge or vacuum manifold.
&nbsp;
<h2>What You Will Find</h2>
&nbsp;
<ul>
<li>Streamlined high-throughput processing using 96-well plate formats for simultaneous genomic DNA purification.</li>
<li>High-purity DNA extraction from blood and tissue samples using optimized purification chemistries.</li>
<li>Compatibility with both automated and manual workflows for scalable sample preparation in research and diagnostic laboratories.</li>
<li>Purified DNA suitable for sequencing, PCR, qPCR, genotyping, and other downstream molecular biology applications.</li>
</ul>
<h2>&nbsp;</h2>
<h2>How to Choose a 96-Well Plate Blood and Tissue Genomic DNA Kit</h2>
&nbsp;
Sample Input and Well Capacity
Most kits accept up to 200 &micro;L of whole blood, serum, plasma, or approximately 5 &times; 106 cultured cells per well. Exceeding recommended input volumes can reduce DNA binding efficiency and overall recovery.
Centrifuge Rotor vs. Vacuum Manifold Compatibility
96-well plate kits typically require either a centrifuge equipped with a compatible 96-well plate rotor and deep bucket carriers or a vacuum manifold system. If your laboratory lacks a plate-compatible centrifuge, confirm vacuum manifold compatibility before selecting a kit.
Yield and Elution Volume
A typical extraction yields approximately 6 &micro;g of genomic DNA from 200 &micro;L of whole blood, with elution volumes commonly around 200 &micro;L using TE buffer or nuclease-free water. Processing times generally range from 45 minutes to a few hours, depending on workflow design.
Throughput and Sample Type Considerations
These kits are optimized for high-throughput processing and can handle large sample batches efficiently. When processing multiple sample types within the same plate, additional pretreatment steps may be required for certain tissues or cell types.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
The key specifications for 96-well plate genomic DNA extraction kits include sample input volume, DNA yield, elution volume, and compatibility with centrifuge-based or vacuum-manifold workflows. Most kits in this category are designed for high-throughput purification of genomic DNA from blood, tissue, and cultured cell samples while maintaining consistent recovery across large sample batches.&nbsp;Products such as the Quick-DNA 96 Kit, Quick-DNA 96 Plus Kit, 96-well Blood DNA Kit, and 96-well Tissue DNA Kit support parallel processing in a plate-based format, helping laboratories scale routine genotyping, PCR, qPCR, and sequencing workflows. Typical workflows combine optimized lysis and silica-based DNA binding chemistry to remove inhibitors while producing purified DNA suitable for downstream molecular biology applications.&nbsp;When selecting a kit, confirm compatibility with your laboratory's centrifuge rotor, 96-well carrier, or vacuum manifold system, as equipment requirements vary between platforms. Most kit components are stored at room temperature, while any included enzyme reagents should be stored according to the manufacturer's recommendations. Lot-specific Certificates of Analysis (CoAs) are available upon request.
&nbsp;
<a href="https://mbpinc.net/contact-us">Contact the MBP team </a>today to discuss high-throughput genomic DNA extraction workflows and receive expert guidance on selecting the right 96-well plate solution for your laboratory.

96-well plate

DataSheet

Quick-DNA 96 Kit

D3010 Quick-DNA 96 Kit by Zymo Research purifies inhibitor-free genomic DNA (≤5 µg/well, ≥40 kb) from whole blood, cells, and tissue in a 2×96-well plate format. Compatible with PCR, genotyping, bisulfite conversion, and NGS.

Shipping Condition

Storage Condition

ZR-96 Quick-DNA™ Kit (2 x 96 Preps.)

ZR-96 Quick-DNA™ (4 x 96 Preps.)

ZR-96 Quick-DNA™ (10 x 96 Preps.)

D4070-Data Sheet

D4070 - MSDS

D4070-Protocol

Quick-DNA 96 Plus Kit

D4070 by Zymo Research: Quick-DNA™ 96 Plus Kit, 2×96 preps. Extracts genomic DNA from biofluids, cells, and solid tissues. 5 µg/well binding capacity; ≥15 µl elution; Proteinase K digestion at 55°C. Typical yield: 5–7 µg from 100 µl whole blood. Made in USA.

Elution Volume

Purity

Workflow

Yield

Quick-DNA™ 96 Plus Kit (2 x 96 Preps.)

Quick-DNA™ 96 Plus Kit (4 x 96 Preps.)

<h2>What Are Spin-Column Genomic DNA Kits for Blood and Tissue?</h2>
&nbsp;
A spin-column genomic DNA kit for blood and tissue combines a proteinase K-based direct lysis step with a silica-membrane spin column to purify genomic, mitochondrial, or viral DNA from animal blood, tissue, and cultured cells without phenol, chloroform, or alcohol precipitation. Related entities include direct-lysis protocols, dried blood spot supplementary workflows, TissueLyser mechanical disruption, and downstream PCR, genotyping, and sequencing library preparation.&nbsp;Use spin-column formats for individual or small-batch genomic DNA extraction from blood, cells, or tissue using a standard microcentrifuge.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li>Efficient isolation of high-quality genomic DNA from blood, saliva, tissues, and other biological samples using rapid spin-column purification.&nbsp;</li>
<li>Maximize DNA recovery with optimized lysis and binding chemistry while minimizing inhibitor, protein, and contaminant interference</li>
<li>Midiprep, microprep, and miniprep formats available to support varied sample input volumes&nbsp;</li>
<li>User-friendly workflows and streamlined protocols with fast processing times for efficient genomic DNA extraction&nbsp;</li>
</ul>
&nbsp;
<h2>How to Choose a Spin-Column Blood/Tissue Genomic DNA Kit</h2>
&nbsp;
Lysis Approach by Sample Type
Whole blood, buffy coat, buccal cells, and cultured cells generally undergo direct proteinase K lysis without mechanical disruption. In contrast, fibrous or fatty tissues such as muscle, liver, or skin often require mechanical homogenization prior to the lysis step to ensure complete cell disruption.
Anticoagulant and Blood Sample Handling
These kits typically support fresh or frozen blood collected in EDTA, citrate, or heparin. Dried blood spots generally require supplementary protocols and additional equipment beyond standard spin-column workflows.
Column Elution Chemistry
Elution is typically performed using Tris-based buffer or nuclease-free water, with volumes ranging from approximately 50&ndash;200 &micro;L depending on kit design and sample type. Water elution may be preferred for EDTA-sensitive downstream applications.
Scaling Beyond a Single Column
For higher throughput workflows, 96-well plate formats using the same silica-membrane chemistry enable simultaneous processing of multiple samples per centrifuge run. Spin-column formats remain best suited for method development and low-to-moderate sample volumes.
&nbsp;
<h2>Specifications Context:</h2>
&nbsp;
The most important parameters for spin-column blood/tissue genomic DNA kits are sample-type compatibility and elution buffer composition, as these determine whether additional pretreatment is required and whether the eluate is directly compatible with downstream workflows. A typical 200 &micro;L whole blood input yields low-microgram quantities of genomic DNA in an elution volume of approximately 50&ndash;200 &micro;L.
&nbsp;
Use MBP's <a href="mbpinc.net/quickorder">Quick Order tool</a> for bulk pricing or <a href="mbpinc.net/contact-us">contact the specialist team</a> to confirm pretreatment requirements for challenging tissue types.

Spin-column

Quick-DNA Microprep Kit

C2010 by Zymo Research — 2-pack of Zymo-Spin™ I-96-XL deep-well 96-well purification plates for high-throughput HMW DNA (up to 5 µg/well) and RNA (up to 10 µg/well) purification. 1.1 ml well capacity; elution in ≥ 15 µl per well. Centrifuge-compatible. Pair with Air Permeable Sealing Cover (C2011-2).

Quick-DNA™ MicroPrep (50 Preps.)

Quick-DNA™ MicroPrep (200 Preps.)

Quick-DNA Miniprep

D3024 by Zymo Research is the Quick-DNA™ Miniprep Kit (50 preps) for rapid, Proteinase K-free gDNA isolation from whole blood (up to 200 µl), plasma, serum, cultured cells, and buccal samples—yielding 3–7 µg per 100 µl blood (up to 25 µg total) with A260/A280 &gt;1.8, DNA up to 40 kb+, in ≥50 µl eluate. The inhibitor-free output is directly compatible with PCR, qPCR, restriction digestion, and bisulfite conversion.

Quick-DNA™ MiniPrep (50 Preps.)

Quick-DNA™ MiniPrep (200 Preps.)

<h2>What Are 96-Well Plate Viral DNA Extraction Kits?</h2>
&nbsp;
A 96-well plate viral DNA extraction kit replaces individual spin columns with a silica-membrane plate, allowing up to 96 cell-free liquid samples to be lysed, bound, washed, and eluted simultaneously using either a centrifuge equipped with a 96-well rotor carrier or a vacuum manifold. These systems support high-throughput viral DNA purification workflows while maintaining the nucleic acid quality required for PCR, qPCR, sequencing, and molecular diagnostics.&nbsp;Choose a 96-well plate viral DNA extraction kit when sample volumes justify batch processing, and your laboratory has compatible centrifuge or vacuum-manifold equipment.
&nbsp;
<h2>What you will find:&nbsp;</h2>
&nbsp;
<ul>
<li>Quick-DNA Viral 96 Kit: Enables efficient parallel processing of up to 96 samples in a single workflow.</li>
<li>Sequencing Ready: Produces purified viral nucleic acids suitable for next-generation sequencing applications.</li>
<li>PCR &amp; qPCR Compatible: Delivers high-quality DNA and RNA for PCR, qPCR, and RT-qPCR workflows.</li>
<li>Molecular Diagnostics Support: Ideal for high-throughput viral screening and diagnostic research applications.</li>
</ul>
<h2>&nbsp;</h2>
<h2>How to Choose a 96-Well Plate Viral DNA Extraction Kit</h2>
&nbsp;
Centrifuge Rotor and Minimum Speed Requirements
Most 96-well plate kits require a centrifuge equipped with a compatible 96-well plate rotor or carrier. Some systems specify minimum centrifugal forces around 2,250 &times; g and sufficient bucket depth to accommodate the plate format. Confirm equipment compatibility before selecting a kit.
Vacuum Manifold Compatibility
Many plate-based viral DNA extraction kits can also be operated using a vacuum manifold instead of centrifugation. This option is particularly useful for laboratories already utilizing vacuum-based nucleic acid purification workflows.
Elution Volume and DNA Concentration
Some kits support elution volumes as low as 6&ndash;10 &micro;L of DNase/RNase-free water, enabling recovery of highly concentrated viral DNA suitable for low-titer samples and sensitive qPCR applications. Larger elution volumes may be preferable when sample concentration is less critical, and ease of handling is a priority.
Throughput and Workflow Efficiency
While plate-format kits generally have a higher upfront cost than individual spin-column kits, they significantly reduce hands-on time per sample when processing large batches. Laboratories routinely processing dozens of samples per run typically benefit most from plate-based workflows.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
The most important specifications for 96-well plate viral DNA extraction kits are sample input capacity, minimum elution volume, and equipment compatibility requirements. Many systems process up to 400 &micro;L of sample per well and support low-volume elution for concentrated DNA recovery.&nbsp;Plate-based workflows are commonly adopted by laboratories transitioning from single-column extraction methods to higher-throughput operations. By combining silica-membrane purification with automation-friendly formats, these kits help standardize viral DNA extraction across large sample sets while maintaining consistent performance for downstream PCR, qPCR, and sequencing applications.
&nbsp;
<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> today to discuss your high-throughput viral DNA extraction requirements and receive expert guidance on selecting the right 96-well plate solution for your laboratory workflow.

Quick-DNA Viral 96 Kit

D3017 by Zymo Research is a 96-well viral DNA isolation kit providing 2 × 96 preps. Accepts ≤200 µl whole blood, plasma, serum, tissue, or cultured cells; elutes in ≥10 µl with A260/A280 ≥1.8 and DNA spanning 100 bp–50 kb. Compatible with qPCR, NGS, PCR, Southern blotting, and restriction digestion.

Processing Volume

Quick-DNA™ Viral 96 Kit (2 x 96 Preps.)

Quick-DNA™ Viral 96 Kit (4 x 96 Preps.)

<h2>What are FFPE DNA extraction kits?</h2>
&nbsp;
An FFPE DNA extraction kit purifies genomic DNA from formalin-fixed, paraffin-embedded tissue sections through a deparaffinization step (xylene-free in most current kits), proteinase K digestion to lyse fixed tissue, heat treatment to reverse formalin-induced crosslinks, and silica-membrane spin column purification, with some kits offering an optional uracil-N-glycosylase (UNG) treatment to remove deaminated-cytosine artifacts before NGS. Choose an FFPE-specific kit rather than a standard tissue kit whenever your sample is formalin-fixed and paraffin-embedded, since standard kits don't include deparaffinization or crosslink-reversal steps.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" aria-level="1">Quick-DNA&trade; FFPE MiniPrep for rapid isolation of high-purity genomic DNA from FFPE tissue samples for high-throughput downstream applications.</li>
<li data-section-id="1n7706u" data-start="258" data-end="375">Designed to recover highly fragmented and cross-linked DNA suitable for sensitive downstream molecular workflows.</li>
<li data-section-id="355glt" data-start="376" data-end="494">Streamlined workflow supports rapid processing of FFPE samples with minimal hands-on time and reduced sample loss.</li>
<li data-section-id="125uabh" data-start="495" data-end="611">Optimized for compatibility with high-throughput applications, including PCR, sequencing, and genotyping assays.</li>
<li data-section-id="10hv3na" data-start="612" data-end="731" data-is-last-node="">Ensures consistent DNA yield and purity from challenging archived tissue specimens for reliable experimental results.</li>
</ul>
&nbsp;
<h2>How to choose an FFPE DNA extraction kit</h2>
&nbsp;
Deparaffinization chemistry
Most current FFPE DNA kits use a proprietary, xylene-free Deparaffinization Solution that dissolves paraffin without multiple wash steps, though some published methods use mineral oil as a simple alternative deparaffinization approach. Xylene-free chemistry reduces hands-on time and avoids handling a hazardous solvent, which matters for labs without dedicated solvent fume hoods.
Crosslink reversal and artifact removal
Formalin fixation creates DNA-protein crosslinks that block PCR unless reversed, so FFPE kits include a heat-based de-crosslinking step after lysis; some kits add an optional UNG treatment before a second lysis step to remove deaminated-cytosine artifacts, which is specifically useful for reducing C-to-T and G-to-A transition artifacts in NGS data. If your downstream application is NGS or dPCR on long-archived samples, a kit with UNG treatment is worth the extra step.
Sample input and elution volume
FFPE kits typically recommend 6-8 tissue sections of 5-10 um thickness as input, with some kits offering elution volumes as low as 15-30 ul for concentrated DNA suitable for limited-input downstream assays. If your archived sections are scarce, prioritize kits that minimize sample loss during deparaffinization rather than requiring multiple wash steps.
Expected DNA quality and fragment size
DNA from FFPE samples is inherently fragmented due to formalin fixation, and downstream applications involving fragments under 200 bp are generally achievable with effective deparaffinization and extraction; PCR success rates around 97% across microsatellite markers have been reported with optimized protocols on long-archived specimens. Set expectations for fragment size and PCR success rate based on sample age and fixation duration rather than assuming fresh-tissue-equivalent quality.
&nbsp;
<h2>Specifications context</h2>
&nbsp;
The key specs for FFPE DNA extraction are deparaffinization chemistry (xylene-free vs. solvent-based), whether crosslink reversal and optional UNG artifact removal are included, and elution volume relative to your sample's scarcity. A kit recommending 6-8 sections per extraction with elution as low as 15-30 ul concentrates limited archived material for downstream PCR or NGS. Labs working with both fresh and archived samples often keep&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/blood/tissue">blood/tissue genomic DNA kits</a>&nbsp;for fresh/frozen tissue alongside a dedicated FFPE kit for archived specimens, since standard tissue kits lack deparaffinization chemistry. The parent&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna">genomic DNA extraction kits hub</a>&nbsp;and broader&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits">DNA extraction kits hub</a>&nbsp;link to related sample-type categories, including&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/urine">urine DNA extraction kits</a>&nbsp;and&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/insect">insect genomic DNA kits</a>&nbsp;for other specialized sample types.&nbsp;
&nbsp;
<section class="mbp-contact-cta">
MBP's specialist team can help match kit chemistry, format, and throughput to your sample type and downstream application.&nbsp;<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> for personalized guidance.
</section>

FFPE

Quick-DNA™ FFPE MiniPrep

D3067 by Zymo Research is the Quick-DNA FFPE MiniPrep Kit (50 preps) for extracting up to 25 µg of DNA from FFPE tissue samples into ≥50 µl with A260/A280 ≥1.8 purity. Includes Deparaffinization Solution and Zymo-Spin IIC columns; fragment size selection available for &gt;50 bp (qPCR) or &gt;500 bp (NGS) targets. Compatible with fresh/frozen tissue. Requires microcentrifuge and heat block (55 °C and 90 °C). Made in USA by Zymo Research.

Quick-DNA™ FFPE MiniPrep (50 Preps.)

Deparaffinization Solution (20 ml)

Genomic DNA Wash 1 (25 ml)

Genomic DNA Wash 2 (12 ml)

<h2>What Are Magnetic Bead Genomic DNA Kits for Blood and Tissue?</h2>
&nbsp;
Magnetic bead genomic DNA kits for blood and tissue use paramagnetic beads to capture genomic DNA released during sample lysis. Following DNA binding, a magnetic separator immobilizes the beads, and contaminants are removed by wash steps before purified DNA is eluted. Unlike spin-column workflows, magnetic bead protocols eliminate centrifugation and simplify automation, making them well-suited to high-throughput laboratories and automated liquid-handling systems.
Magnetic bead extraction is often selected when automation, reduced hands-on processing, or compatibility with high-throughput workflows is a priority. Specialized high-molecular-weight (HMW) magnetic bead chemistries are also available for applications requiring longer DNA fragments for advanced sequencing workflows.
&nbsp;
<h2>What you will find:</h2>
&nbsp;
<ul>
<li>Quick-DNA&trade; Magbead Plus Kit: Magnetic bead-based genomic DNA purification for blood, tissue, cultured cells, and other biological samples.</li>
<li>Automation-Compatible Workflows: Designed for seamless integration with manual and automated magnetic separation platforms.</li>
<li>High-Yield DNA Recovery: Optimized to produce purified genomic DNA suitable for PCR, qPCR, genotyping, sequencing, and other downstream molecular biology applications.</li>
<li>Streamlined Sample Processing: Eliminates centrifugation steps through magnetic bead technology, simplifying genomic DNA extraction workflows.</li>
</ul>
<h2>&nbsp;</h2>
<h2>How to Choose a Magnetic Bead Genomic DNA Kit for Blood and Tissue</h2>
&nbsp;
Sample Input and Processing Time
Most magnetic bead kits are designed to process approximately 100-400 &micro;L of whole blood or buffy coat per preparation. Tissue and cultured cell inputs vary by kit but generally support small tissue samples and several million cells per extraction. Manual workflows can often be completed in about 20 minutes because centrifugation steps are eliminated.
Yield and Purity Requirements
Magnetic bead extraction kits are capable of producing high-quality genomic DNA suitable for PCR, qPCR, genotyping, sequencing, Southern blotting, and related molecular biology applications. DNA purity is commonly comparable to silica-based purification methods, making these kits suitable for most downstream workflows.
Automation Compatibility
One of the primary advantages of magnetic bead chemistry is its compatibility with automated liquid handling platforms. Because DNA capture and washing occur through magnetic separation rather than centrifugation, these workflows can be readily adapted to 96-well and higher-throughput automated formats.
High-Molecular-Weight DNA Applications
Some magnetic bead systems are specifically optimized for high-molecular-weight genomic DNA recovery. These workflows can preserve larger DNA fragments required for long-read sequencing, linked-read assembly, structural variation analysis, and other applications where DNA integrity is critical.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
Magnetic bead genomic DNA extraction kits are differentiated by their centrifuge-free workflow, automation compatibility, and flexibility across blood, buffy coat, tissue, and cultured cell samples. The magnetic separation process reduces manual handling steps while supporting consistent DNA recovery and scalable throughput.&nbsp;Many laboratories adopt magnetic bead workflows when transitioning from manual extraction methods to automated sample preparation systems. Compared with traditional spin-column methods, magnetic bead purification simplifies integration with robotic liquid handlers and high-throughput extraction platforms while maintaining DNA quality suitable for PCR, qPCR, sequencing, and genotyping applications.&nbsp;When selecting a kit, evaluate sample input requirements, automation compatibility, DNA purity specifications, and whether high-molecular-weight DNA recovery is required for downstream applications. Most kit reagents are stored according to manufacturer recommendations, and lot-specific Certificates of Analysis (CoAs) are available upon request.
&nbsp;
<a href="https://mbpinc.net/contact-us">Contact the expert team at MBP</a> to get high-quality mag beads for blood/tissue genomic DNA extraction workflows to scale up your laboratory throughput.

Mag Beads

D4081-Data Sheet

D4081-1-MSDS

D4081-2-MSDS

D4081-3-MSDS

D4081-Protocol

Quick-DNA™ Magbead Plus Kit

D4081 by Zymo Research is the Quick-DNA™ Magbead Plus Kit, a magnetic bead-based platform for total DNA extraction (genomic, mitochondrial, and viral) from biological fluids, cells, and solid tissues in a 96-well format, with Proteinase K included and automation scripts available for KingFisher, Tecan, Hamilton, and Opentrons OT-2. The kit recovers DNA fragments up to 150 kb and processes 96 samples in approximately 60 minutes.

Quick-DNA™ Magbead Plus Kit (96 Preps.)

Quick-DNA™ Magbead Plus Kit (4 x 96 Preps.)

Solid Tissue Digestion Buffer II (22 ml)

Solid Tissue Digestion Buffer II (6 ml)

BioFluid & Solid Tissue Buffer (100 ml)

BioFluid & Solid Tissue Buffer (25 ml)

D4074-Data Sheet

D4074-MSDS

D4074-Protocol

Quick-DNA™ Microprep Plus Kit (50 Preps.)

D4074 by Zymo Research — Quick-DNA™ Microprep Plus Kit (50 preps) for high molecular weight genomic DNA extraction (&gt; 50 kb) from tissues, blood, saliva, cell cultures, and biological fluids. 20-minute protocol; elution ≤ 10 µl; binding capacity up to 5 µg. Ready for qPCR, NGS, and microarray.

D4075-Data Sheet

D4075 - MSDS

D4075-Protocol

Quick-DNA™ Midiprep Plus Kit (25 Preps.)

D4075 Quick-DNA Midiprep Plus Kit by Zymo Research — 25 preps; &gt;50 kb genomic DNA; 125 &micro;g column capacity; &le;200 &micro;l elution; tissues, blood, cells, FFPE, hair, and bone.

D4068-Data Sheet

D4068/D4068T - MSDS

D4069 - MSDS

D4068-Quick Protocol

D4068-Protocol

Quick-DNA™ Miniprep Plus Kit

D4068 by Zymo Research — Quick-DNA™ Miniprep Plus Kit with Proteinase K; 20-minute protocol; ≥35 µL elution; 25 µg capacity; >50 kb recovery; A260/A230 ≥ 2.0; for tissue, blood, saliva, and biological fluids. 10, 50, or 200 preps.

BioFluid & Cell Buffer (Red) (6 ml)

BioFluid & Cell Buffer (Red) (12 ml)

BioFluid & Cell Buffer (Red) (25 ml)

BioFluid & Cell Buffer (Red) (45 ml)

Solid Tissue Buffer (Blue) (10 ml)

Solid Tissue Buffer (Blue) (22 ml)

Solid Tissue Buffer (Blue) (6 ml)

Genomic Binding Buffer (25 ml)

Genomic Binding Buffer (45 ml)

Genomic Binding Buffer (85 ml)

Quick-DNA™ Miniprep Plus Kit (10 Preps.)

Quick-DNA™ Miniprep Plus Kit (200 Preps.)

Quick-DNA™ Miniprep Plus Kit (50 Preps.)

<h2>What are 96-well plate plant genomic DNA kits?</h2>
&nbsp;
A 96-well plate plant genomic DNA kit replaces individual spin columns with a silica binding plate, processed by a centrifuge with a 96-well rotor carrier, to purify genomic DNA from up to 96 plant tissue samples per run using CTAB- or SDS-based lysis chemistry adapted to a plate format. Related entities include plate-based pre-filtration steps for polysaccharide removal, high-throughput genotyping and marker-assisted breeding workflows, and downstream PCR and SNP genotyping applications. Choose the 96-well plate format for plant genomic DNA when weekly sample numbers across multiple individuals or accessions justify batch processing on a plate-compatible centrifuge.
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<h2>What you will find:</h2>
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<ul>
<li>Quick-DNA&trade; Plant/Seed 96 Kit for rapid vacuum manifold processing using silica-membrane 96-well plant DNA plates</li>
<li>Silica-membrane 96-well plates deliver consistent genomic DNA recovery for downstream PCR and genotyping</li>
<li>Optimized plant and seed DNA extraction workflow supports efficient large-scale breeding and research projects</li>
</ul>
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<h2>How to choose a 96-well plate plant genomic DNA kit</h2>
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Lysis chemistry consistency across the plate
Because all 96 wells are processed together, lysis chemistry (CTAB vs. SDS) needs to suit every sample on the plate; mixing species with very different polysaccharide or polyphenol content on one plate can mean some wells underperform if the chemistry is not matched to the most demanding sample type. Validate lysis chemistry on individual spin columns for a new species before committing to plate-scale runs.
Centrifuge rotor and pre-filtration in plate format
96-well plant DNA kits require a centrifuge with a 96-well rotor carrier, and pre-filtration to remove polysaccharides and debris is typically built into the plate workflow using a pre-filter plate stacked above the binding plate rather than a separate Maxi column. Confirm your centrifuge accepts the stacked-plate configuration the kit specifies.
Tissue input per well and plate layout
Each well in a 96-well plant DNA kit typically accepts a similar tissue mass to a single spin-column preparation, under 100 mg fresh weight, so plate layouts should account for tissue collection and loading time per well alongside the extraction itself. For breeding programs processing many individuals per accession, planning plate layout by population or family can simplify downstream genotyping data handling.
Throughput vs. species diversity
A single 96-well plant DNA plate is most efficient when processing many samples of the same or closely related species with similar metabolite profiles; highly diverse sample sets may be better split across plates by lysis chemistry requirement. Estimate species diversity within a typical batch before committing to one chemistry for an entire plate run.
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<h2>Specifications Context</h2>
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The defining specifications for a 96-well plate plant genomic DNA kit are lysis chemistry suitability across all samples on the plate, centrifuge rotor and stacked pre-filter plate compatibility, and per-well tissue input consistent with spin-column equivalents. A kit processing under 100 mg fresh tissue per well with matched CTAB or SDS chemistry and built-in pre-filtration scales the same yield range, roughly 1&ndash;30 micrograms, across 96 samples per run. Breeding and genotyping programs often validate lysis chemistry using <a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/plant/spin-column">plant spin-column kits</a> for a new species or accession set before committing to plate-scale batches with this format.
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<a href="https://mbpinc.net/contact-us">Contact the expert team </a>at MBP today and get high-throughput extraction using an optimized 96-well system.

MSDS (EU)

MSDS (US)

User Manual

Quick-DNA™ Plant/Seed 96 Kit (2 x 96 Preps.)

D6021 by Zymo Research — Quick-DNA™ Plant/Seed 96 Kit; 2 × 96 preps; processes stems, roots, leaves, fruits, and seeds (≤80 mg input); BashingBead™ lysis; ≥50 µL elution; inhibitor-free DNA for qPCR, NGS, and arrays.

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