Erlenmeyer Flasks Accessories

<h2 dir="ltr">&nbsp;What are Erlenmeyer Flask Accessories?</h2>
 Erlenmeyer flask accessories are the replacement caps, transfer cap assemblies, vent filters, and adapter fittings used alongside PC and PETG shake flasks to customize gas exchange, enable closed-system liquid transfer, and replace consumable caps between culture runs. Accessory selection determines whether a shake flask acts as a standard culture vessel, a sealed storage container, or a closed-system liquid transfer assembly in a cGMP workflow.
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<h2 dir="ltr">What you will find:</h2>
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<ul>
<li>Accessories compatible with high-efficiency Erlenmeyer flasks in 2 L, 3 L, and 5 L formats.</li>
<li>Available in bi-directional, inverted, and multifunctional transfer cap configurations.</li>
<li>Supports both standard-neck and wide-mouth 3 L flask designs.</li>
<li>Includes options with integrated silicon tubing for transfer applications.</li>
<li>Enables customization of flask workflows through interchangeable transfer cap accessories.</li>
</ul>
<h2 dir="ltr">&nbsp;</h2>
<h2 dir="ltr">How to Choose Erlenmeyer Flask Accessories</h2>
 Vented Caps: Standard vs. Oversized Membrane Standard vented Erlenmeyer caps have a 0.22 &micro;m PTFE membrane in a small-diameter HDPE housing. NEST Scientific vented caps feature an oversized membrane area that increases the gas exchange surface, supporting higher oxygen mass transfer for dense suspension cultures at elevated shaker speeds. At 150 RPM with 20&ndash;25% fill, NEST oversized vented caps provide sufficient oxygen transfer for mammalian suspension cultures at densities up to approximately 5 &times; 10⁶ cells/mL. For cultures targeting densities above 10 &times; 10⁶ cells/mL in a standard shake flask format, a sparged bioreactor system is more appropriate. Plug Seal Caps: Autoclave vs. Non-Autoclave HDPE plug seal caps for NEST PC Erlenmeyer flasks are compatible with autoclave cycles at 121 &deg;C when loosened 1&ndash;1.5 turns before autoclaving to prevent steam pressure buildup. Plug seal caps for NEST PETG flasks are compatible with static incubation and transport but not autoclaving (PETG maximum temperature: +60 &deg;C). Confirm whether your accessory cap is rated for autoclave use before including it in a steam sterilization cycle. Transfer Cap Assemblies for Closed-System Culture NEST customized transfer cap assemblies combine an Erlenmeyer-compatible cap body with a bi-directional transfer port, TPE tubing, and a Luer lock or CPC connector &mdash; enabling aseptic inoculation, sampling, or media addition to a running shake flask culture without opening the flask. This closed-system capability is used in cGMP process development, GMP seed train management, and contamination-critical research workflows. Transfer caps are available in sizes matching NEST 125 mL, 250 mL, 500 mL, 1,000 mL, 2,000 mL, and 3,000 mL flask neck formats. Cap Sizing and Flask Compatibility Erlenmeyer flask caps are sized to the neck thread diameter of the flask. NEST Scientific PC and PETG Erlenmeyer flasks use proprietary screw-thread neck dimensions &mdash; confirm the specific cap catalog number matches your flask's neck size before ordering replacement caps. Do not mix cap brands across flask brands without verifying thread compatibility; mismatched caps create gas leaks at the vent membrane, contaminating cultures. Replacement Cap Frequency for Reusable PC Flasks For reusable PC flasks, replace the vented cap after each culture run to prevent membrane clogging from media splatter, condensation, and biofilm formation on the PTFE membrane. Reusing a contaminated or clogged vent membrane reduces gas exchange efficiency, creating a DO deficit that depresses cell growth without a visible contamination event. NEST vented caps for PC flasks are available in bulk packs for cost-efficient per-run replacement. 
<h2 dir="ltr"> Specifications Context</h2>
 NEST Scientific Erlenmeyer flask accessories &mdash; including replacement vented caps, plug seal caps, and transfer cap assemblies &mdash; are manufactured from USP Class VI HDPE (cap housing) and USP Class VI PTFE (0.22 &micro;m membrane), with TPE tubing in transfer assemblies. All accessory caps are sterile and non-pyrogenic per the lot certificate. The 0.22 &micro;m membrane pore size is the standard for microbial retention in cell culture venting applications. Transfer cap assemblies compatible with the NEST Erlenmeyer flask line are available in sizes for 125 mL through 3,000 mL flasks, individually wrapped in sterile packaging. NEST Scientific is ISO 9001:2015 and ISO 13485 certified.&nbsp; 
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Erlenmeyer Flask Accessories

DataSheet

2L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap

C10122-AZB050B by NEST Scientific is a bi-directional liquid transfer cap for 2 L Erlenmeyer flasks featuring a 50 cm TPE tube (1/8" ID), 0.22 µm hydrophobic PTFE vent filter, and a Colder Products MPC connector. E-beam sterilized to SAL 10⁻⁶ per ISO 11137; supplied 1/sterile bag, 4/cs. Flask not included.

Manufacturer

2L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ24mm), without Flask , Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/4" ID 3/8" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Male CPC Connector with Female Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Female CPC Connector with Male Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Inverted Transfer Cap

NEST Scientific C10131-AZC050B is a sterile inverted transfer cap for 2 L High Efficiency Erlenmeyer Flasks, featuring a 50 cm TPE tube (1/8″ ID × 1/4″ OD) and a 0.22 μm vent filter for closed-system liquid transfer in bioprocess and cell culture applications. Sold without flask; 1/pk, 4/cs.

2L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ42mm), without Flask , Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap

C10111-AJE052B by NEST Scientific is a multifunctional transfer cap for 2 L High Efficiency Erlenmeyer flasks. Pre-assembled with a 52 cm TPE tube (1/8" ID × 1/4" OD), T-junction Luer lock sampling nozzle, and 0.22 µm PTFE vent filter (Φ50 mm). E-beam sterilized to SAL 10⁻⁶. Cap only, sterile, 1/pk, 4/cs.

2L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube (52cm 1/8" ID 1/4" OD) and a Sampling Nozzle, Vent Filter (0.22 μm Φ50mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube ( 50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

2L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with Silicon Tube (100cm 3/16" ID 3/8" OD), Male CPC Connector with Female Sealing Cap, Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap

NEST Scientific C10222-AZB050B: bi-directional transfer cap for 3 L High Efficiency Erlenmeyer Flasks with 50 cm TPE tube (1/8" ID, 1/4" OD) and 0.22 µm vent filter. Enables closed-system liquid transfer without cap removal. Sterile, 1/pk, 4/cs. Order at <a href="https://www.mbpinc.net/quickorder">mbpinc.net/quickorder</a>.

3L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/4" ID 3/8" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Male CPC Connector with Female Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Female CPC Connector with Male Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Inverted Transfer Cap

NEST Scientific C10231-AZC050B is a sterile inverted transfer cap for 3 L High Efficiency Erlenmeyer Flasks — 50 cm TPE tube (1/8″ ID × 1/4″ OD), 0.22 μm vent filter (Φ42 mm), closed-system one-directional liquid transfer. Sold without flask. Sterile, 1/pk, 4/cs.

3L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube ( 50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap

C10211-AJE052B by NEST Scientific — multifunctional transfer cap for 3 L high efficiency Erlenmeyer flasks. Includes 52 cm TPE tube (1/8&quot; ID &times; 1/4&quot; OD), integrated sampling nozzle, 0.22 &mu;m &times; 50 mm vent filter. Sterile, cap only, 1/pk, 4/cs.

3L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube (52cm 1/8" ID 1/4" OD) and a Sampling Nozzle, Vent Filter (0.22 μm Φ50mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube ( 50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with Silicon Tube (100cm 3/16" ID 3/8" OD), Male CPC Connector with Female Sealing Cap, Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap

C10322-AZB050B by NEST Scientific is a 3 L wide-mouth polycarbonate Erlenmeyer flask with baffles and a bi-directional transfer cap for contamination-free closed-system liquid transfer in mammalian and insect cell culture bioprocessing. The cap includes a 50 cm TPE tube (1/8&Prime; ID &times; 1/4&Prime; OD) and an integrated 0.22 &micro;m vent filter (&Phi;24 mm) for aseptic media addition and harvest. Manufactured to cGMP standards under ISO 13485 certification; sterile, 1/pk, 4/cs.

3L Wide-mouth High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/4" ID 3/8" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Male CPC Connector with Female Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (50cm1/4" ID 3/8" OD), Female CPC Connector with Male Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Inverted Transfer Cap

C10331-AZC050B by NEST Scientific is an inverted transfer cap for 3 L wide-mouth High Efficiency Erlenmeyer flasks. The inverted design allows near-complete closed drainage when the flask is flipped. Pre-assembled with 50 cm TPE tube (1/8" ID × 1/4" OD) and 0.22 µm PTFE vent filter (Φ42 mm). E-beam sterile, SAL 10⁻⁶. Cap only, 1/pk, 4/cs.

3L Wide-mouth High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (50cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap

NEST Scientific C10311-AJE052B: multifunctional transfer cap for 3 L wide-mouth High Efficiency Erlenmeyer Flasks with 52 cm TPE tube (1/8" ID, 1/4" OD), integrated sampling nozzle, and 0.22 µm vent filter (Φ50 mm). Closed-system liquid transfer and in-process sampling without flask opening. Sterile, 1/pk, 4/cs. Order at <a href="https://www.mbpinc.net/quickorder">mbpinc.net/quickorder</a>.

3L Wide-mouth High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube (52cm 1/8" ID 1/4" OD) and a Sampling Nozzle, Vent Filter (0.22 μm Φ50mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube ( 50cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

3L Wide-mouth High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with Silicon Tube (100cm 3/16" ID 3/8" OD), Male CPC Connector with Female Sealing Cap, Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap

NEST Scientific C10422-AZB090B is a sterile bi-directional transfer cap for 5 L High Efficiency Erlenmeyer Flasks — 90 cm TPE tube (1/8″ ID × 1/4″ OD), 0.22 μm vent filter (Φ24 mm), supports both media addition and culture drain through a single closed-system connection. Sold without flask. 1/pk, 4/cs.

5L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (90cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with TPE Tube (50cm 1/4" ID 3/8" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (90cm1/4" ID 3/8" OD), Male CPC Connector with Female Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Bi-directional Transfer Cap with Silicon Tube (90cm1/4" ID 3/8" OD), Female CPC Connector with Male Sealing Cap with, Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Inverted Transfer Cap

The C10431-AZC090B by NEST Scientific is an inverted transfer cap for the 5 L NEST High Efficiency Erlenmeyer Flask, enabling closed-system liquid transfer that minimizes external contamination risk during media handling and bioprocess operations. Features a 90 cm transfer tube, 0.22 µm vent filter, and ships sterile to SAL 10⁻⁶. Packed 1 per pack, 4 per case.

5L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube (90cm 1/8" ID 1/4" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Inverted Transfer Cap with TPE Tube ( 90cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ42mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap

C10411-AJE092B by NEST Scientific is a sterile multifunctional transfer cap for 5 L High Efficiency Erlenmeyer Flasks, with 92 cm weldable TPE tubing (1/8" ID × 1/4" OD), sampling nozzle with one-way valve, and a 0.22 µm vent filter (Φ50 mm). Enables closed-system liquid transfer and aseptic sampling. SAL 10⁻⁶, endotoxin-free, animal-origin-free; 1/pk, 4/cs.

5L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube (92cm 1/8" ID 1/4" OD) and a Sampling Nozzle, Vent Filter (0.22 μm Φ50mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with TPE Tube ( 90cm 1/4" ID 7/16" OD), Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

5L High Efficiency Erlenmeyer Flask Multifunctional Transfer Cap with Silicon Tube (100cm 3/16" ID 3/8" OD), Male CPC Connector with Female Sealing Cap, Vent Filter (0.22 μm Φ24mm), without Flask, Sterile, 1/pk, 4/cs

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