Deep Well Plates

Square Well Deep Well Plates

<h2 data-section-id="7nn2n" data-start="0" data-end="42">What Are Square Well Deep Well Plates?</h2>
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Square well deep well plates are polypropylene microplates designed with square-shaped wells instead of traditional round wells. This design maximizes liquid capacity within the standard SBS/ANSI microplate footprint, making them ideal for high-throughput laboratory workflows that require larger sample volumes. Commonly available in 96-well formats with capacities ranging from 1.1 mL to 2.2 mL per well, these plates are widely used for nucleic acid extraction, protein precipitation, compound library storage, sample preparation, and automated liquid handling.
The square-well geometry increases usable volume while maintaining compatibility with automated platforms from Hamilton, Tecan, Beckman Coulter, and Agilent. Manufactured from virgin polypropylene, square well plates offer excellent chemical resistance to DMSO, ethanol, acetonitrile, and extraction buffers, while minimizing sample binding and contamination risks.
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<h2 dir="ltr">Product Range:</h2>
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96-square well storage plates for sample management.
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2.2ml deep well plates for large-volume handling.
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V-bottom square well plates for maximum sample recovery.
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DNA-free deep well microplates for molecular applications.
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Medical-grade polypropylene plates for chemical durability.
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Automation-ready square well formats for robotic integration.
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Deep well plates for bead beating and high-impact use.
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Chemical-resistant 96-well plates for harsh reagents.
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<h2 data-section-id="1lthnju" data-start="1133" data-end="1179">How to Choose Square Well Deep Well Plates</h2>
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Well Volume The most common formats are 2.0 mL and 2.2 mL square well plates, which provide sufficient volume for nucleic acid extraction, protein precipitation, and compound storage workflows. Lower-profile 1.1 mL plates are useful when deck height limitations or freezer space optimization are important considerations.
Bottom Geometry V-bottom wells concentrate liquid and pellets into a single point, enabling more complete aspiration and improved recovery during centrifugation-based workflows. U-bottom wells promote better mixing and resuspension, making them suitable for microbial culture applications and serial dilutions.
Centrifugation Requirements Most square well polypropylene plates are compatible with centrifugation speeds between 4,000 &times; g and 6,000 &times; g. For demanding extraction protocols, reinforced plate designs provide additional structural stability during high-speed centrifugation.
Automation Compatibility Select plates that comply with ANSI/SLAS standards and include molded alphanumeric indexing for sample tracking. Features such as stacking lugs and raised well rims improve robotic handling and sealing performance.
Certification Standards For molecular biology applications, choose plates manufactured from virgin polypropylene and certified DNase-free, RNase-free, DNA-free, and PCR inhibitor-free. Sterile options are recommended for sensitive workflows and regulated environments.
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<h2 data-section-id="u7fdje" data-start="3248" data-end="3283">Specifications and Applications</h2>
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Square well deep well plates are typically manufactured from high-purity polypropylene and operate across a wide temperature range, often from approximately &ndash;86&deg;C to +125&deg;C. Most plates conform to ANSI/SLAS microplate dimensions (127.76 &times; 85.48 mm), ensuring compatibility with automated liquid handlers, centrifuges, incubators, and storage systems.
Today, 2.0 mL and 2.2 mL square well V-bottom plates remain the preferred format in pharmaceutical research, clinical diagnostics, genomics laboratories, and biobanking facilities due to their high volume capacity, efficient liquid recovery, and seamless integration into automated workflows.
Upgrade your lab with durable essentials that won't fail during critical runs. Browse our website and <a href="https://mbpinc.net/contact-us" style="color: #236fa1; text-decoration: underline;">request a quote from the team at MBP</a> for your supplies.

1.2ml 96 Square Well, Deep Well Plates

MBPDSW12-V — 1.2 mL per well, 96 square wells, V-bottom deep well plate, SBS-standard footprint, 100 plates/case. For high-throughput sample processing and automated liquid handling.

Manufacturer

Round Well Deep Well Plates

<h2 data-section-id="8npnrj" data-start="0" data-end="40">What are Round Well Deep Well Plates?</h2>
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Round well deep well plates are polypropylene microplates manufactured to ANSI/SLAS (SBS) footprint standards, featuring cylindrical wells that provide greater sample volumes than standard PCR or assay plates. Typical formats include 96-well plates with capacities of 1.2 mL, 2.0 mL, or 2.2 mL per well, designed for automated sample processing, nucleic acid extraction, microbial culture, compound storage, and high-throughput laboratory workflows.
The round well geometry promotes uniform mixing, consistent liquid movement during shaking, and efficient magnetic bead collection during automated extraction procedures. Unlike square well plates, which maximize storage volume, round well plates are preferred when sample recovery, mixing performance, and magnetic bead handling are critical.
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<h2 dir="ltr">What you will find:</h2>
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96-round well storage plates
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1.2ml deep well plates
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2.0ml round well plates
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Sterile deep well microplates
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DNase and RNase-free plates
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U-bottom deep well plates
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Polypropylene storage plates
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Automation-compatible round well plates
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Silicone sealing mats
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<h2 data-section-id="m2xmka" data-start="1392" data-end="1436">How to Choose Round Well Deep Well Plates</h2>
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Well Volume
The 1.2 mL round well plate is specified for smaller-input nucleic acid extraction protocols (blood, plasma, swab) and fits automated deck formats with restricted Z-height clearance. The 2.0 mL round well format accommodates larger sample input volumes for high-yield extractions and is the standard format for Nest Scientific deep well plates used in nucleic acid processing. Confirm working volume versus total well volume in the product specification &mdash; a 2.0 mL plate typically has a total volume of 2,200&ndash;2,400 &micro;L.
Bottom Geometry
U-bottom (hemispherical) round wells are standard for sample storage, bacterial and cell culture, and general liquid handling where complete aspiration is not required. V-bottom (conical) round wells concentrate liquid and pellet to the lowest point for complete aspiration and enhanced pellet recovery, preferred in enzymatic assay and precipitation protocols. Flat-bottom round well plates are used when an optical flat surface is needed for absorbance-based assay measurement.
Sterility Requirements
Non-sterile round well deep well plates manufactured in ISO 8 cleanrooms satisfy most nucleic acid extraction and sample processing workflows. Sterile options (gamma-irradiated, SAL 10⁻⁶) are required for cell culture, bacterial culture, and RNA extraction from live cells. Autoclavable polypropylene formats provide a cost-effective reusable sterile option for labs with autoclave access.
Centrifugation and Sealing
Standard round well deep well plates are rated 4,000&ndash;6,000 &times; g. Raised well rims ensure consistent sealing with adhesive films, heat-seal foils, and pre-slit silicone mats. Nest Scientific 96-well round well silicone sealing mats (pre-slit, 7 mm diameter) are compatible with 0.35&ndash;1.35 mL round well plates.
Automation Compatibility
Specify virgin polypropylene, lot-certified DNase-free, RNase-free, DNA-free, and PCR inhibitor-free for nucleic acid extraction. Nest Scientific deep well plates use USP Class VI polypropylene material with high chemical stability for demanding extraction workflows.
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<h2 data-section-id="1jl751w" data-start="4818" data-end="4843">Specifications Context</h2>
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Round well deep well plates are manufactured from high-purity polypropylene and are commonly rated for temperatures from &minus;80&deg;C to +121&deg;C, supporting freezer storage and autoclave sterilization. Premium plates are produced from USP Class VI resins and tested for DNase, RNase, DNA, and PCR inhibitor contamination.
The 96-well 2.0 mL U-bottom round well plate remains one of the most widely used formats for automated nucleic acid extraction, biobanking, bacterial culture, and sample preparation workflows due to its balance of volume capacity, automation compatibility, and reliable magnetic bead performance.
Browse our range and <a href="https://mbpinc.net/contact-us" style="color: #236fa1; text-decoration: underline;">request a quote from the MBP team</a> to find the right fit for your lab.

1.2ml Deep Well Plates Abgene

AB-12DWP by MBP — 96-well, 1.2 mL round U-bottom deep well plate; medical-grade PP; ANSI/SLAS SBS footprint; certified DNase/RNase-free; rated to 2,000 × g; 50 plates/case.

2.0ML Deep Well Plates Hamilton

HM-20DWP is a sterilized 96-well deep well plate with 2.0 mL U-bottom circular wells, supplied 50 plates per case. Designed for Hamilton automated liquid handling platforms (STAR, STARlet, Nimbus). Suitable for sample storage, extraction workflows, and high-throughput compound arraying.

2.2ml Square well U bottom Deep Plate

MBPDSW22-UB by MBP — 96-well deep-well plate, 2.2 mL/well, U-bottom, half-skirted, ultra-thin wall medical-grade PP, DNase/RNase/endotoxin-free, 6,000 RCF rated.

2ml Deep Well Plate Nunc

MBP20CU by Nunc — 96-well deep well plate, 2 mL/well, U-bottom round wells, non-treated polypropylene, ANSI/SLAS standard footprint. Compatible with robotic liquid handlers and multichannel pipettors. Supplied 50 plates per case.

Kingfisher Plastics

<h2 data-section-id="144nuix" data-start="0" data-end="40">What Are KingFisher Flex Consumables?</h2>
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KingFisher Flex consumables are specialized plates, tip combs, and accessories designed specifically for Thermo Scientific KingFisher magnetic particle processors, including the KingFisher Flex, Apex, Duo Prime, and Presto systems. These consumables are engineered to support automated magnetic bead-based purification workflows for DNA extraction, RNA isolation, protein purification, cell isolation, and other molecular biology applications. Their precise dimensions and well geometries ensure accurate magnetic rod movement, efficient bead transfer, and consistent purification results across high-throughput laboratory workflows.
Unlike standard deep well plates, KingFisher consumables are manufactured from low-binding polypropylene to minimize the loss of nucleic acids and proteins during extraction and washing steps. This helps maximize sample recovery, improve purity, and maintain reproducibility in research, clinical diagnostics, biobanking, and next-generation sequencing (NGS) applications.
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<h2 dir="ltr">At MBP, You can discover:</h2>
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6 Deep-Well Plates for KingFisher Flex and Presto systems
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24-Well Deep Well Plates for high-volume extraction
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96-Format Plastic Tip Combs for magnetic bead collection
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U-bottom Square Well Plates for minimal volume
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10.4 ml 24-well plates for large-scale purification
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Medical-grade Polypropylene Plates for chemical stability
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Sterile, DNase/RNase-free consumables for sensitive assays
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High-recovery extraction plates for maximum specimen yield
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<h2 data-section-id="1h779p8" data-start="1262" data-end="1306">How to Choose KingFisher Flex Consumables</h2>
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Instrument Configuration
Consumable selection depends on the instrument model and processing head installed. Most KingFisher Flex systems use a 96-well head designed for medium-throughput sample processing, while certain applications require a 24-well head for larger sample volumes. Always verify your instrument configuration before ordering consumables.
Sample Volume Requirements
The 96-well format is ideal for routine DNA and RNA extraction from blood, plasma, swabs, tissue lysates, and cultured cells. Applications requiring larger input volumes, such as circulating cell-free DNA isolation, environmental testing, or stool sample processing, often use the 24-well format, which accommodates significantly larger volumes per well.
Sterility Requirements
Non-sterile consumables are commonly used for standard nucleic acid purification and protein extraction workflows. Sterile plates and sterile plate-tip comb combination packs are recommended for cell-based applications, sensitive RNA workflows, and any procedure requiring aseptic processing conditions.
Individual Components vs. Combination Packs
Many laboratories purchase plates and tip combs separately to match workflow requirements. Combination packs containing both sterile plates and matching sterile tip combs simplify inventory management and ensure compatibility between components.
Downstream Application
For PCR, qPCR, sequencing, and library preparation workflows, purified samples are typically transferred into 96-well microplates with smaller working volumes. Applications requiring larger elution volumes may use deep well plates for the final collection step.
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<h2 data-section-id="1jl751w" data-start="3463" data-end="3488">Specifications Context</h2>
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KingFisher consumables are manufactured from high-purity, low-binding polypropylene to reduce non-specific adsorption of DNA, RNA, proteins, and magnetic beads. They are produced under strict quality control standards to ensure dimensional consistency and compatibility with automated magnetic particle processors.
These consumables are widely used in molecular diagnostics, genomics, biobanking, pharmaceutical research, and clinical laboratories. Their standardized design supports reproducible extraction performance while maintaining compatibility with automated sample preparation workflows.
For laboratories requiring more general automation-compatible sample processing plates, deep well plates provide SBS-format compatibility with liquid handling systems from Hamilton, Tecan, Beckman Coulter, and other automation platforms. Immunoassay and ELISA workflows, however, require specialized assay plates designed for optical detection rather than magnetic bead processing.&nbsp;
Lock your combs, load your plates, and let the automation handle the precision. Request a quote from <a href="https://mbpinc.net/contact-us" style="color: #236fa1; text-decoration: underline;">the team at Molecular Biology Products Inc</a> today.

Kingfisher Flex Consumables

KingFisher Flex Consumables for 96 Deep-Well Format

MBPDSW22 by MBP: 96 deep-well V-bottom polypropylene consumables for the Thermo Scientific KingFisher Flex, Duo Prime, Presto, and MagMAX 96. Stocked in US and Canadian warehouses; six-year zero-quality-issue record. Contact MBP for volume pricing.