Cryogenic Storage

Cryogenic Vials

<h2>What Are Cryogenic Vials?</h2>
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Cryogenic vials are specialized screw-cap laboratory containers manufactured from cryogenic-grade virgin polypropylene (PP) and designed to withstand extreme temperatures ranging from &minus;196&deg;C in liquid nitrogen storage to +121&deg;C during steam autoclaving. They serve as the primary storage vessel for biological materials requiring long-term preservation, including cell lines, serum, plasma, blood samples, DNA, RNA, microbial cultures, and other biospecimens. Common vial capacities include 1.2 mL, 1.5 mL, 1.8 mL, 2 mL, 3 mL, and 5 mL, with the 2 mL format being the most widely used standard for cell culture and biobanking applications. Most cryogenic vials feature leak-resistant screw caps with silicone sealing gaskets and dedicated writing areas for sample identification. For storage in liquid nitrogen, it is important to use vials specifically certified for cryogenic applications, as standard laboratory tubes are not designed to tolerate temperatures as low as &minus;196&deg;C.
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<h2>What You Will Find:</h2>
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<ul>
<li><a href="https://mbpinc.net/consumables/cryogenic-storage/cryogenic-vials/cryo-boxes" title="Cryo Boxes">Cryo Boxes:</a> High-durability polycarbonate storage systems with integrated grids for rapid, indexed sample retrieval in ultra-low environments.</li>
<li><a href="https://mbpinc.net/consumables/cryogenic-storage/cryogenic-vials/freezer-boxes" title="Freezer Boxes">Freezer Boxes:</a> Moisture-resistant and stackable organizers designed to maximize space and maintain thermal consistency within -20 degree celsius and -80 degree celsius freezers.</li>
<li><a href="https://mbpinc.net/consumables/cryogenic-storage/cryogenic-vials/externally-threaded-cryogenic-vials" title="Externally Threaded Cryogenic Vials">Externally Threaded Cryogenic Vials</a>: Designed with threads on the outside of the vial to minimize contamination risk and maximize the internal volume for sample storage.</li>
<li><a href="https://mbpinc.net/consumables/cryogenic-storage/cryogenic-vials/internally-threaded-cryogenic-vials" title="Internally Threaded Cryogenic Vials">Internally Threaded Cryogenic Vials</a>: Featuring a silicone O-ring seal and internal threads to provide the most secure, leak-proof closure for vapor-phase LN2 storage.</li>
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<h2>How to Choose Cryogenic Vials</h2>
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Thread Type: Internal vs. External
Thread design influences both contamination control and workflow compatibility. Internal-thread vials position the sealing mechanism inside the neck of the vial, reducing the external surface area exposed to contaminants and making them a common choice for cell culture and biosafety-sensitive applications. External-thread vials place the threads on the outside of the vial neck, maximizing internal storage volume and improving compatibility with automated capping, decapping, and robotic handling systems. Laboratories using automated biobanking workflows often prefer external-thread formats.
Volume Selection
Vial capacity should match the intended sample type and storage requirements. The 1.8&ndash;2.0 mL size is commonly used for cell lines, serum aliquots, and general biospecimen storage because it fits standard cryogenic storage boxes. Smaller 1.2 mL formats support high-density storage of limited-volume samples, while larger 3&ndash;5 mL vials are suitable for tissue specimens, bacterial glycerol stocks, and applications requiring larger sample volumes.
Sterility and Purity Certification
For cell culture, molecular biology, and clinical research applications, cryogenic vials should be supplied with certifications confirming they are RNase-free, DNase-free, non-pyrogenic, and endotoxin-free. Many laboratories also prefer gamma-sterilized vials, which reduce contamination risk and eliminate the need for additional sterilization before use. Traceable lot documentation and certificates of conformity are often required in regulated environments.
Self-Standing vs. Round Bottom Designs
Self-standing cryogenic vials feature a molded base that allows them to remain upright on laboratory benches without additional support, reducing the risk of spills during sample handling. Round-bottom designs are compatible with a broader range of storage racks and cryogenic systems but generally require a rack or holder during bench-top use. The choice largely depends on laboratory workflow and storage equipment.
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<h2>Specifications Context</h2>
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Cryogenic vials are typically manufactured from high-purity polypropylene because of its excellent durability and resistance to ultra-low temperatures. Products intended for liquid nitrogen immersion should carry explicit certification for liquid-phase storage, as some vials are approved only for vapor-phase applications. Vial dimensions, particularly outer diameter, determine compatibility with freezer boxes, racks, and automated storage systems, so measurements should be confirmed before mixing products from different manufacturers. Modern biobanking facilities increasingly use externally threaded, 2D-barcoded cryogenic vials integrated with laboratory information management systems (LIMS) to improve inventory tracking, sample traceability, and large-scale repository management.
Protect your research legacy. <a href="https://mbpinc.net/contact-us">Connect with the Molecular Biology Products Inc. team</a> for a custom quote on our complete cryogenic storage range.

Cryogenic Vial Brochure

Picker for CryoClear vials, TPE, Blue, 10/Bag

30078 by Globe Scientific is a blue thermoplastic elastomer (TPE) cryogenic vial picker designed for safe retrieval of CryoClear vials from storage boxes. The picker engages the notch on the CryoClear cap, allowing single-vial extraction without direct hand contact, glove removal, or disturbance of adjacent samples. TPE remains flexible at cryogenic temperatures. Supplied 10/bag. Order

Manufacture

3032-1-Group-RingSeal Cryogenic Vials Brochure

3032-1-Group-Cryogenic Vial Comparison Guide

RingSeal Cryogenic Vials with External Threads Specifications

RingSeal Cryogenic Vials with External Threads

3032-1 by Globe Scientific is a 1.0 mL RingSeal cryogenic vial with external threads and an integrated O-ring seal rated to 90 kPa and −196°C. Made from virgin polypropylene and certified RNase-free, DNase-free, and pyrogen-free, the RingSeal vial is sterile and autoclavable for long-term biobanking and clinical sample archiving. Order via mbpinc.net/quickorder using catalog number 3032-1.

Cryogenic Vials, 1.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Conical Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 2.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 2.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 4.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 5.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 5.0mL, STERILE, External Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Printed Graduations and Writing Space, CS/500

3034-1-Group-RingSeal Cryogenic Vials Brochure

3034-1-Group-Cryogenic Vial Comparison Guide

3034-1-Group-TDS 3032-1

3034-1-Group-TDS 3032-2

3034-1-Group-TDS 3032-2-RB

3034-1-Group-TDS 3032-4

3034-1-Group-TDS 3032-5

3034-1-Group-TDS 3032-5-RB

3034-1-Group-TDS 3034-1

3034-1-Group-TDS 3034-2

RingSeal Cryogenic Vials with Internal Threads Specifications

RingSeal Cryogenic Vials with Internal Threads

The 3034-1 by Globe Scientific is a 1.0 mL RingSeal Cryogenic Vial with internal threads, a self-standing base, and an O-ring–sealed attached screwcap rated from –196°C to +121°C with 90 kPa leak-proof performance. Made from virgin polypropylene and certified RNase-free, DNase-free, and Pyrogen-free, each vial is supplied sterile and is autoclavable at 121°C for 15 minutes.

Cryogenic Vials, 1.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Conical Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 2.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 2.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 4.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 5.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Self-Standing, Printed Graduations and Writing Space, CS/500

Cryogenic Vials, 5.0mL, STERILE, Internal Threads, Attached Screwcap with O-Ring Seal, Round Bottom, Printed Graduations and Writing Space, CS/500

Cryo Boxes

<h2>What Are Cryo Boxes?</h2>
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Cryo boxes are lidded, gridded storage containers designed to organize cryogenic vials, microcentrifuge tubes, and centrifuge tubes inside ultra-low temperature (ULT) freezers at &minus;80&deg;C, vapor-phase liquid nitrogen refrigerators (&minus;150 to &minus;190&deg;C), and cryogenic dewars. The two primary materials are water-resistant coated cardboard (economical, single-use) and rigid polycarbonate or polypropylene (reusable, autoclavable, transparent). Standard well configurations&mdash;25 (5&times;5), 81 (9&times;9), and 100 (10&times;10)&mdash;in 2-inch and 3-inch box heights match common cryogenic vial sizes. The alphanumeric grid on the lid helps with sample tracking in LIMS systems. Cardboard cryo boxes are vapor-phase LN2 rated only; polycarbonate is required for autoclave use or liquid-phase LN2 immersion.
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<h2>What you will find:</h2>
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&bull; Standard cryo boxes for cryogenic vial storage &bull; Freezer storage boxes for ultra low temperature use &bull; Cardboard cryo boxes for cost effective storage &bull; Polypropylene cryo boxes for durability and reuse &bull; Grid format boxes for easy sample organization &bull; Hinged lid cryo boxes for quick access &bull; Color coded storage boxes for sample identification &bull; Cryo storage boxes for 1.5 mL and 2.0 mL vials
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<h2>How to Choose Cryo Boxes</h2>
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Material: Cardboard vs. Polycarbonate vs. Polypropylene
Cardboard cryo boxes are economical and used for long-term storage at &minus;80&deg;C or vapor-phase LN2. They are single-use and not autoclavable. Polycarbonate (PC) boxes are durable, transparent, and autoclavable at 121&deg;C, making them suitable for frequent handling. Polypropylene (PP) boxes also tolerate autoclaving and offer higher chemical resistance than PC. Choice depends on reuse frequency and sterilization needs.
Well Count and Vial Size
81-well (9&times;9) boxes fit standard 1.8&ndash;2.0 mL cryogenic vials up to ~13 mm outer diameter. 100-well (10&times;10) boxes are used for smaller 1.2&ndash;1.5 mL vials and microcentrifuge tubes up to ~12 mm OD. Always match vial diameter with box well size before ordering.
Box Height: 2-Inch vs. 3-Inch
2-inch boxes are standard for 1&ndash;2 mL cryovials and are most commonly used in biobanking. 3-inch boxes are for larger 3&ndash;5 mL vials and certain centrifuge tubes where extra depth is required.
LN2 Phase Compatibility
Both cardboard and hard-wall boxes can be used in vapor-phase LN2. Only polycarbonate or polypropylene boxes should be used for liquid-phase LN2 because cardboard can break down when submerged.
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<h2>Specifications Context</h2>
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Cryo boxes are typically rated from &minus;196&deg;C to +121&deg;C depending on material. Cardboard is suitable for vapor-phase LN2 only, while hard-wall plastic boxes can handle more demanding workflows. Proper selection depends on vial size, storage temperature, and how frequently samples are accessed.
Eliminate the risk of thermal damage. <a href="https://mbpinc.net/contact-us" style="color: #236fa1; text-decoration: underline;">Connect with the experts at Molecular Biology Products Inc.</a> to find the perfect storage solution for your high-value specimens.

3049-Group-Cryogenic Vial Brochure

Workstation Racks for CryoClear Vials

Globe Scientific polycarbonate workstation rack (SKU 3049) — 40-position (10×4 format) for CryoCLEAR cryogenic vials, round-bottom and self-standing. Autoclavable at 121°C, anti-slip rubber feet, one-handed cap removal. Available in blue (3049B), green (3049G), and red (3049R) for colour-coded sample organisation.

Workstation Rack for CryoCLEAR vials, Polycarbonate (PC), 40-Place (10x4 format), BLUE, BOX/5

Workstation Rack for CryoCLEAR vials, Polycarbonate (PC), 40-Place (10x4 format), GREEN, BOX/5

Workstation Rack for CryoCLEAR vials, Polycarbonate (PC), 40-Place (10x4 format), RED, BOX/5

Item Specifications

CryoClear Cryogenic Vials with External Threads

3010 by Globe Scientific is a 1.0 mL CryoClear cryogenic vial with external threads, a self-standing conical bottom, and a co-molded TPE sealing layer rated to −196°C. Each vial is beta-radiation sterile (SAL 10⁻⁶), ISO 7 cleanroom-manufactured, and individually barcoded, with lot certification for human-DNA-free, RNase-free, DNase-free, pyrogen-free, and ATP-free purity. Available from MBP in cases of 500; order via mbpinc.net/quickorder using catalog number 3010.

CryoCLEAR vials, 1.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Conical Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 1.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Conical Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

 CryoCLEAR vials, 2.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoCLEAR vials, 3.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 3.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoCLEAR vials, 4.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 4.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoCLEAR vials, 5.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 5.0mL, STERILE, External Threads, Attached Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag

CryoClear Cryogenic Vials with External Threads with Color-Coded Caps

Globe Scientific CryoCLEAR externally threaded cryogenic vials with colour-coded caps (SKU 3012X) — ISO 7 cleanroom, beta-radiation sterilised (SAL 10&#8722;6), certified human DNA-free, RNase/DNase-free, ATP-free, non-cytotoxic, BSE/TSE-free. Co-moulded TPE seal, star socket cap, per-vial barcode. Available 1–5 mL. Rated -196°C to +121°C; vapour-phase LN₂ only.

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled BLUE Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled GREEN Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled RED Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled VIOLET Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled WHITE Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

CryoCLEAR vials, 2.0mL, STERILE, External Threads, Assembled YELLOW Screwcap with Co-Molded Thermoplastic Elastomer (TPE) Sealing Layer, Round Bottom, Self-Standing, Printed Graduations, Writing Space and Barcode, 50/Bag, 10 Bags/Case

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