Biomiga

<h2>What Are 96-Well Plate Genomic DNA Kits for Blood and Tissue?</h2>
&nbsp;
96-well plate genomic DNA kits for blood and tissue replace individual spin columns with silica-binding or glass-fiber plates that enable simultaneous purification of genomic, mitochondrial, or pathogen DNA from up to 96 samples per run. These systems are designed for whole blood, serum, plasma, lymphocytes, cultured cells, and selected tissue samples, providing efficient high-throughput DNA extraction for research and molecular testing workflows.&nbsp;Choose a 96-well plate genomic DNA kit when sample volumes justify batch processing on a plate-compatible centrifuge or vacuum manifold.
&nbsp;
<h2>What You Will Find</h2>
&nbsp;
<ul>
<li>Streamlined high-throughput processing using 96-well plate formats for simultaneous genomic DNA purification.</li>
<li>High-purity DNA extraction from blood and tissue samples using optimized purification chemistries.</li>
<li>Compatibility with both automated and manual workflows for scalable sample preparation in research and diagnostic laboratories.</li>
<li>Purified DNA suitable for sequencing, PCR, qPCR, genotyping, and other downstream molecular biology applications.</li>
</ul>
<h2>&nbsp;</h2>
<h2>How to Choose a 96-Well Plate Blood and Tissue Genomic DNA Kit</h2>
&nbsp;
Sample Input and Well Capacity
Most kits accept up to 200 &micro;L of whole blood, serum, plasma, or approximately 5 &times; 106 cultured cells per well. Exceeding recommended input volumes can reduce DNA binding efficiency and overall recovery.
Centrifuge Rotor vs. Vacuum Manifold Compatibility
96-well plate kits typically require either a centrifuge equipped with a compatible 96-well plate rotor and deep bucket carriers or a vacuum manifold system. If your laboratory lacks a plate-compatible centrifuge, confirm vacuum manifold compatibility before selecting a kit.
Yield and Elution Volume
A typical extraction yields approximately 6 &micro;g of genomic DNA from 200 &micro;L of whole blood, with elution volumes commonly around 200 &micro;L using TE buffer or nuclease-free water. Processing times generally range from 45 minutes to a few hours, depending on workflow design.
Throughput and Sample Type Considerations
These kits are optimized for high-throughput processing and can handle large sample batches efficiently. When processing multiple sample types within the same plate, additional pretreatment steps may be required for certain tissues or cell types.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
The key specifications for 96-well plate genomic DNA extraction kits include sample input volume, DNA yield, elution volume, and compatibility with centrifuge-based or vacuum-manifold workflows. Most kits in this category are designed for high-throughput purification of genomic DNA from blood, tissue, and cultured cell samples while maintaining consistent recovery across large sample batches.&nbsp;Products such as the Quick-DNA 96 Kit, Quick-DNA 96 Plus Kit, 96-well Blood DNA Kit, and 96-well Tissue DNA Kit support parallel processing in a plate-based format, helping laboratories scale routine genotyping, PCR, qPCR, and sequencing workflows. Typical workflows combine optimized lysis and silica-based DNA binding chemistry to remove inhibitors while producing purified DNA suitable for downstream molecular biology applications.&nbsp;When selecting a kit, confirm compatibility with your laboratory's centrifuge rotor, 96-well carrier, or vacuum manifold system, as equipment requirements vary between platforms. Most kit components are stored at room temperature, while any included enzyme reagents should be stored according to the manufacturer's recommendations. Lot-specific Certificates of Analysis (CoAs) are available upon request.
&nbsp;
<a href="https://mbpinc.net/contact-us">Contact the MBP team </a>today to discuss high-throughput genomic DNA extraction workflows and receive expert guidance on selecting the right 96-well plate solution for your laboratory.

96-well plate

R6811 96 well RNA. Purification Kit

96-well Tissue DNA Kit

96-well Tissue, Eukaryotic cells RNA purification Kit: Purify up to 100μg total RNA from 5×106 Eukaryotic cells or 30 mg tissue.\n

Manufacturer

96-well Tissue DNA Kit , 1x96 Preps

96-well Tissue DNA Kit , 4x96 Preps

96-well Tissue DNA Kit , 20x96 Preps

<h2>What are 96-Well Plate Total RNA Extraction Kits?</h2>
&nbsp;
96-well plate total RNA extraction kits purify total RNA from up to 96 samples in a single processing run using silica-membrane plates, glass-fiber filter plates, or magnetic bead formats compatible with centrifuges, vacuum manifolds, or automated liquid handlers. Unlike single-tube spin-column formats, plate kits maintain individual sample integrity while delivering the throughput needed for screens, longitudinal studies, and genomics pipelines processing hundreds of samples per week.&nbsp;Choose a 96-well plate format when processing 48 or more samples per session to eliminate the per-sample handling overhead of individual spin columns.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" aria-level="1">
Direct-zol&trade;-96 RNA Kits facilitate bypass of the phase-separation steps, enabling phenol-free, high-throughput transcript extraction directly from TRIzol&reg; reagents&nbsp;
</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" aria-level="1">
Quick-RNA&trade; 96 Kits for rapid, ultra-pure total RNA delivery from small-scale cellular samples
</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" aria-level="1">
96-well Tissue RNA Kits with multi-well lysis arrays to handle complex, fibrous animal tissues without blocking the filtration matrices
</li>
</ul>
&nbsp;
<h2>How to Choose a 96-Well Plate RNA Extraction Kit</h2>
&nbsp;
Processing Method: Centrifuge vs. Vacuum vs. Magnet
Centrifuge-compatible plates (e.g., QIAGEN RNeasy 96) require a 96-well plate rotor; vacuum manifold protocols skip that equipment dependency. Magnetic bead formats eliminate both and are the preferred choice when an automation platform is available. Select based on the equipment already in your facility before comparing kits.
Sample Type and Starting Amount
Standard plate kits handle 100-2x10^6 cultured mammalian cells or up to 30 mg of tissue per well. Plant tissue extraction requires an additional plant isolation aid to remove polysaccharide and polyphenol inhibitors. Do not use total RNA kits for cell-free samples (plasma, serum, nasal wash) - those require viral RNA formats.
On-Plate DNase Treatment
For RT-qPCR and RNA-seq, choose kits that include on-plate DNase I digestion to remove genomic DNA contamination. Most silica-membrane kits supply lyophilized DNase I; verify that the kit includes this reagent rather than requiring a separate purchase.
Elution Volume and Concentration
96-well kits typically elute in 50-100 ul per well; magnetic bead formats can concentrate into 20-50 ul, which is advantageous for low-abundance samples or applications needing high RNA concentration for library prep.
Automation Compatibility
Magnetic bead 96-well formats integrate with Tecan, Hamilton, and Beckman Coulter liquid handlers using vendor-supplied scripts. Silica-membrane plates can be semi-automated on vacuum manifold platforms. Confirm the kit supplier provides an automation protocol before purchase if robotic processing is required.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
Key purity benchmarks for 96-well RNA eluates are A260/A280 &gt;= 1.8 and A260/A230 &gt;= 1.5; values below these thresholds indicate carryover of protein, phenol, or guanidinium salts that inhibit downstream enzymes. Silica-membrane kits from QIAGEN and Bio-Rad remain the most widely cited 96-well formats in peer-reviewed methods, and their protocols are referenced directly in published automation workflows at institutions including the Howard Hughes Medical Institute. RNase-free reagents and consumables are required throughout to prevent RNA degradation; confirm kit buffers are certified RNase-free before use with precious or low-abundance samples.
<section class="mbp-contact-cta">
&nbsp;
MBP's specialist team can help match kit chemistry, format, and throughput to your sample type and downstream application.&nbsp;<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> for personalized guidance.
</section>

Product Literature

96-well Tissue RNA Kit

96-well Tissue RNA Kit , 1x96 Preps

96-well Tissue RNA Kit , 4x96 Preps

96-well Tissue RNA Kit , 20x96 Preps

<h2>What Are Spin-Column Viral DNA Extraction Kits?</h2>
&nbsp;
Spin-column viral DNA extraction kits combine a chaotropic lysis and binding buffer with a silica-membrane spin column housed in a collection tube, allowing viral DNA to be purified using a standard laboratory microcentrifuge. Following lysis, viral nucleic acids bind to the membrane while contaminants are removed during wash steps before purified DNA is eluted for downstream analysis.&nbsp;Choose a spin-column viral DNA extraction kit when processing low-to-moderate sample volumes and when a standard benchtop microcentrifuge provides a more practical solution than a 96-well plate workflow.
&nbsp;
<h2>What You Will Find</h2>
&nbsp;
<ul>
<li>Obtain high-quality viral nucleic acids using spin-column-based purification for PCR, qPCR, sequencing, and molecular diagnostic applications.</li>
<li>Mini and maxi purification formats for efficient concentration and isolation of adenovirus, lentivirus, retrovirus, and adeno-associated virus (AAV).</li>
<li>Optimized workflows that minimize inhibitors and maximize downstream compatibility for fast, reproducible recovery of viral nucleic acids.</li>
<li>Scalable purification options supporting both low-throughput and high-throughput virology, infectious disease, and molecular biology research.</li>
</ul>
&nbsp;
<h2>How to Choose a Spin-Column Viral DNA Extraction Kit</h2>
&nbsp;
Input Sample Volume and Processing Capacity
Most spin-column viral DNA extraction kits accept up to 400 &micro;L of liquid sample per column, with some protocols allowing the same column to be reloaded to process larger total sample volumes. Confirm that your sample type and volume fall within the manufacturer's recommended specifications.
Centrifuge Compatibility
Spin-column purification workflows generally require centrifugation speeds of approximately 10,000 &times; g or greater. Most standard benchtop microcentrifuges used with 1.5&ndash;2 mL tubes can accommodate these requirements, but equipment compatibility should always be verified before implementation.
Elution Buffer Versus Water
Many kits provide the option of eluting DNA with either a storage buffer or DNase/RNase-free water. Elution buffer may be preferable for longer-term storage, while water can be advantageous for downstream applications sensitive to EDTA or other buffer components.
Sample Type Considerations
Spin-column viral DNA extraction kits are optimized primarily for cell-free liquid samples. Protein-rich or solid biological samples may require additional pretreatment steps or may be better served by dedicated genomic DNA extraction kits designed for blood or tissue specimens.
&nbsp;
<h2>Specifications Context</h2>
&nbsp;
The most important performance specifications for spin-column viral DNA extraction kits are sample input capacity and minimum elution volume, as these directly influence DNA concentration and recovery efficiency. A workflow processing several hundred microliters of sample and eluting into a smaller final volume can significantly improve target concentration for downstream qPCR analysis.&nbsp;Many laboratories maintain both spin-column and 96-well plate extraction formats to accommodate varying weekly sample volumes. Spin-column systems offer flexibility and simplicity for smaller studies, while maintaining the DNA quality required for PCR, qPCR, sequencing, and molecular diagnostic applications.
&nbsp;
<a href="https://mbpinc.net/contact-us">Contact the MBP team </a>today to discuss your viral DNA extraction workflow and receive expert guidance on selecting the most suitable spin-column kit for your PCR, qPCR, sequencing, or molecular diagnostics application.

Spin-Column

Adeno-Associated Virus (AAV) Purification Maxi Kit, All Serotypes

The ViraTrapTM AAV purification kit is designed for fast and efficient purification of all rAAV serotypres from AAV infected cell culture.

Adeno-Associated Virus Purification Mini Kit, 3,5,6,8,9 and otherserotypes, 2 Preps

Adeno-Associated Virus Purification Mini Kit, 3,5,6,8,9 and otherserotypes, 4 Preps

Adeno-Associated Virus Purification Mini Kit, 3,5,6,8,9 and otherserotypes, 10 Preps

Adeno-Associated Virus Purification Maxi Kit, serotpye 2 and DJ

Adeno-assiciated viruses, belong to the replication deficient parvovirus family, are small single-stranded DNA viruses. AAVs are important gene delivery tools, which have been used in gene therapy and RNAi delivery.

Adeno-Associated Virus Purification Maxi Kit, serotpye 2 and DJ, 2 Preps

Adeno-Associated Virus Purification Maxi Kit, serotpye 2 and DJ, 4 Preps

Adeno-Associated Virus Purification Maxi Kit, serotpye 2 and DJ, 10 Preps

Adeno-Associated Virus Purification Mini Kit, 3,5,6,8,9 and otherserotypes

Adeno-assiciated viruses, belong to the replication deficient parvovirus family, are small single-stranded DNA viruses. AAVs are important gene delivery tools, which have been used in gene therapy and RNAi delivery.\n

Adeno-Associated Virus Purification Mini Kit, All Serotypes, 2 Preps

Adeno-Associated Virus Purification Mini Kit, 3,5,6,8,9 and otherserotypes, 20 Preps

Adeno-Associated Virus Purification Mini Kit, serotype 2 and DJ

The ViraTrapTM AAV purification kit is designed for fast and efficient purification all serotypres of rAAV from AAV infected cell culture.\n\nViral particles can be purified from cell culture of 1 to 2 T75 flasks per column.

Adeno-Associated Virus Purification Mini Kit, serotype 2 and DJ,2 Preps

Adeno-Associated Virus Purification Mini Kit, serotype 2 and DJ, 10 Preps

Adeno-Associated Virus Purification Mini Kit, serotype 2 and DJ, 20 Preps

Adenovirus Purification Maxi Kit

The ViraTrapTM Adenovirus maxi purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 4 x1012 viral particles can be purified from cell culture media of 6 to 8 T75 flasks.\n

Adenovirus Purification Maxi Kit, 2 Preps

Adenovirus Purification Maxi Kit, 4 Preps

Adenovirus Purification Maxi Kit, 10 Preps

User Manual

MSDS

Adenovirus Purification Mini Kit

The ViraTrapTM adenovirus mini purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 1 x1012 viral particles can be purified from cell culture media of 1 to 2 T75 flasks.\n

Adenovirus Purification Mini Kit, 2 Preps

Adenovirus Purification Mini Kit , 10 Preps

Adenovirus Purification Mini Kit , 20 Preps

<h2>What are plasmid miniprep kits?</h2>
&nbsp;
A plasmid miniprep kit uses SDS/alkaline lysis to break open pelleted E. coli cells from a small culture volume (1-10 ml), followed by binding to a silica-membrane spin column, washing, and elution, separating plasmid DNA from genomic DNA, RNA, and protein in roughly 10-15 minutes per prep. Related entities include Buffer P1/P2/P3-style alkaline lysis reagents, color-coded lysis dyes for visual confirmation of complete lysis and neutralization, RNase A for RNA removal, and downstream applications including transformation, restriction digestion, PCR, and sequencing. Choose a miniprep kit for routine, low-volume plasmid prep (cloning screens, sequencing checks, restriction digests) where yields up to roughly 20-100 ug per column are sufficient.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" role="presentation">Pellet-free and classic plasmid miniprep kits for high-yield bacterial isolation using rapid spin-column workflows</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" role="presentation">High-throughput 96-well plasmid plates optimized for vacuum manifold processing and parallel automated screening&nbsp;</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" role="presentation">Specialized yeast plasmid miniprep systems for fragile fungal hosts using cell-wall digesting chemistries</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" role="presentation">BAC/PAC and large construct isolation units for safer purification of high-molecular-weight vectors</li>
<li dir="ltr" style="font-family: arial, helvetica, sans-serif;" role="presentation">Endotoxin-free plasmid extraction reagents for sensitive mammalian cell lines, ensuring transfection-grade DNA purity&nbsp;</li>
</ul>
&nbsp;
<h2>How to choose a plasmid miniprep kit</h2>
&nbsp;
Standard vs. high-yield chemistry
Standard silica spin-column minipreps typically recover up to about 20 ug per column, while high-yield formulations using modified alkaline lysis and novel binding chemistry can reach up to 100 ug at concentrations up to 3 ug/ul from the same small culture volume. If your downstream application (e.g., sequencing multiple samples from one prep, or transfection requiring more DNA per prep) benefits from a higher concentration, a high-yield kit reduces the need to scale up to midiprep.
Plasmid copy number and culture volume planning
High-copy plasmids (pUC-based vectors) can saturate a miniprep column from as little as 3 ml of culture, yielding around 20 ug, while low-copy plasmids (pBR322, pET, cosmids) may yield under 2 ug from the same volume and benefit from doubling culture volume to 5-10 ml. Identify your vector's origin of replication before choosing a standard culture volume, since low-copy vectors at standard volumes can produce yields too low for some downstream steps.
Color-coded lysis buffers for visual QC
Some miniprep kits include color-coded lysis and neutralization buffers that allow visual confirmation of complete cell lysis (color change) and proper neutralization before loading the column, helping catch incomplete-lysis failures before they waste a column. This visual QC step is particularly useful for new users or when troubleshooting inconsistent yields across a batch of preps.
Endotoxin-free and large-construct options
For transfection-sensitive downstream applications, endotoxin-free miniprep kits add a dedicated wash step without significantly extending the protocol time; for large plasmids, cosmids, or BAC/YAC/PAC constructs, some miniprep kits are validated up to approximately 200 kb, while standard kits are optimized for constructs up to roughly 25 kb. Confirm both endotoxin status and size compatibility match your specific construct and downstream use before relying on a standard miniprep.
&nbsp;
<h2>Specifications context</h2>
&nbsp;
The key specs for plasmid miniprep selection are expected yield relative to your plasmid's copy number and culture volume, whether color-coded buffers aid visual QC, and whether endotoxin-free or large-construct compatibility is needed for your downstream application. A standard miniprep yielding up to roughly 20-25 ug in 10-15 minutes from 1-10 ml of culture covers most routine cloning workflows, while high-yield kits up to 100 ug reduce the need to scale up for moderately DNA-hungry applications. Labs running both daily cloning screens and occasional larger-scale prep work typically keep <a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/plasmid-dna-extraction-kits/miniprep-kits">miniprep kits</a>&nbsp;on hand alongside&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/plasmid-dna-extraction-kits/midiprep-kits">midiprep kits</a>&nbsp;for when miniprep yields aren't sufficient. The parent&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/plasmid-dna-extraction-kits">plasmid DNA extraction kits category</a>&nbsp;and&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/plasmid-dna-extraction-kits/maxiprep-kits">maxiprep kits</a>&nbsp;cover larger-scale options, while the broader&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits">nucleic acid extraction kits hub</a>&nbsp;and&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna">genomic DNA extraction kits category</a> link to chromosomal DNA workflows.&nbsp;
<section class="mbp-contact-cta">
&nbsp;
MBP's specialist team can help match kit chemistry, format, and throughput to your sample type and downstream application.&nbsp;<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> for personalized guidance.
</section>

Miniprep Kits

BAC/PAC Isolation KIt Protocol

BAC/PAC Isolation Kit

The EZgeneTM high-capacity-plasmid DNA Isolation Kit is designed for rapid purification of BAC, PAC, cosmid and P1 from small volume of bacterial cultures. It is based on a modified alkaline lysis procedure that is specially adapted for spin column

BAC/PAC Isolation Kit , 4 Preps

BAC/PAC Isolation Kit , 50 Preps

BAC/PAC Isolation Kit , 250 Preps

<h2>What are microbial and environmental DNA isolation kits?</h2>
&nbsp;
Microbial and environmental DNA isolation kits purify DNA from soil, sediment, freshwater, marine water, feces, and other complex environmental matrices using lysis and purification chemistry designed to remove humic acids, metal compounds, and other inhibitors that interfere with PCR and sequencing, supporting 16S/18S rRNA amplicon profiling and shotgun metagenomic sequencing. Related entities include "kitome" and "splashome" contamination controls, alpha diversity and microbial community composition analysis, and compatibility with both short-read (Illumina) and long-read (Oxford Nanopore) sequencing platforms. Choose a kit validated for your specific sample matrix (soil, sediment, water, or feces), since benchmarking studies consistently show kit performance varies by matrix rather than one kit being universally best.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Spin-column fungal and bacterial kits for rapid DNA purification using rapid silica-membrane technology&nbsp;</li>
<li dir="ltr" role="presentation">Parallel extraction of soil, fecal, and environmental samples using high-throughput 96-well microplates&nbsp;</li>
<li dir="ltr" role="presentation">Automated&nbsp; purification of complex microbial and environmental specimens using Magnetic bead isolation systems</li>
<li dir="ltr" role="presentation">Scalable microprep and midiprep columns tailored for concentrated low-volume elution demands and diverse sample inputs</li>
</ul>
&nbsp;
<h2>How to choose a microbial and environmental DNA isolation kit</h2>
&nbsp;
Matrix-specific kit performance
Benchmarking studies comparing multiple commercial kits across sediment, water, soil, oyster gut microbiome, and mammalian feces have found that the best-performing kit varies by matrix - kits ranked highly for sediment did not necessarily perform best for water or host-associated samples. Rather than assuming a single "universal" kit, match your kit choice to published benchmarking results for your primary sample type where available.
Inhibitor removal for downstream PCR and sequencing
Environmental samples, especially sediments and soils, contain organic and metal compounds that inhibit PCR amplification if not removed during extraction; kits designed for these matrices integrate inhibitor-removal steps as part of the standard protocol. If your samples have historically produced low PCR amplification efficiency with general-purpose kits, an environmental-matrix-specific kit with built-in inhibitor removal is the first thing to evaluate.
Short-read vs. long-read sequencing compatibility
For long-read metagenomic sequencing, DNA fragment length and integrity from the extraction kit directly affect achievable read lengths, though longer extracted fragments don't always translate consistently into longer sequencing reads - kit choice affects both fragment length and downstream classification rate and reproducibility. If long-read metagenomics is your goal, prioritize kits with published long-read benchmarking data over kits validated only for short-read amplicon work.
Contamination control (kitome/splashome)
Kit-derived contamination ("kitome") and cross-sample contamination during processing ("splashome") can affect microbial community composition results, particularly for low-biomass samples; benchmarking studies evaluate kits specifically for these contamination sources alongside yield and diversity metrics. For low-biomass environmental samples, prioritize kits with documented low kitome contamination in published comparisons.
&nbsp;
<h2>Specifications context</h2>
&nbsp;
The key specs for microbial and environmental DNA isolation are matrix-specific validation (soil vs. sediment vs. water vs. feces), built-in inhibitor removal for PCR-ready output, and fragment length/integrity for long-read sequencing compatibility where relevant. Since benchmarking studies repeatedly show no single kit performs best across all matrices, identifying your primary sample type before selecting a kit is the most impactful decision. Labs running metagenomic surveys across multiple matrices (e.g., soil and water from the same field site) often need separate matrix-optimized kits rather than a single universal kit. The parent <a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna">genomic DNA extraction kits hub</a>&nbsp;links to related sample-type categories, including&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/insect">insect genomic DNA kits</a>&nbsp;and&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/genomic-dna/plant">plant genomic DNA kits</a>&nbsp;for organism-associated environmental work, and&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/high-molecular-weight-dna">high molecular weight DNA kits</a>&nbsp;for long-read metagenomics requiring larger fragment sizes. For cell-free DNA in environmental water samples (eDNA detection), see&nbsp;<a href="https://mbpinc.net/reagents/molecular-biology/nucleic-acid-extraction-kits/dna-extraction-kits/cell-free-dna">cell-free DNA kits</a>.&nbsp;
<section class="mbp-contact-cta">
&nbsp;
MBP's specialist team can help match kit chemistry, format, and throughput to your sample type and downstream application.&nbsp;<a href="https://mbpinc.net/contact-us">Contact the MBP team</a> for personalized guidance.
</section>

Microbial & Environmental DNA Isolation

Bacterial DNA Kit

Purify genomic DNA from 1-3 mL bacterial cultures\n

Bacterial DNA Kit , 4 Preps

Bacterial DNA Kit , 50 Preps

Bacterial DNA Kit , 250 Preps

<h2>What Are Spin-Column Genomic DNA Kits for Blood and Tissue?</h2>
&nbsp;
A spin-column genomic DNA kit for blood and tissue combines a proteinase K-based direct lysis step with a silica-membrane spin column to purify genomic, mitochondrial, or viral DNA from animal blood, tissue, and cultured cells without phenol, chloroform, or alcohol precipitation. Related entities include direct-lysis protocols, dried blood spot supplementary workflows, TissueLyser mechanical disruption, and downstream PCR, genotyping, and sequencing library preparation.&nbsp;Use spin-column formats for individual or small-batch genomic DNA extraction from blood, cells, or tissue using a standard microcentrifuge.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li>Efficient isolation of high-quality genomic DNA from blood, saliva, tissues, and other biological samples using rapid spin-column purification.&nbsp;</li>
<li>Maximize DNA recovery with optimized lysis and binding chemistry while minimizing inhibitor, protein, and contaminant interference</li>
<li>Midiprep, microprep, and miniprep formats available to support varied sample input volumes&nbsp;</li>
<li>User-friendly workflows and streamlined protocols with fast processing times for efficient genomic DNA extraction&nbsp;</li>
</ul>
&nbsp;
<h2>How to Choose a Spin-Column Blood/Tissue Genomic DNA Kit</h2>
&nbsp;
Lysis Approach by Sample Type
Whole blood, buffy coat, buccal cells, and cultured cells generally undergo direct proteinase K lysis without mechanical disruption. In contrast, fibrous or fatty tissues such as muscle, liver, or skin often require mechanical homogenization prior to the lysis step to ensure complete cell disruption.
Anticoagulant and Blood Sample Handling
These kits typically support fresh or frozen blood collected in EDTA, citrate, or heparin. Dried blood spots generally require supplementary protocols and additional equipment beyond standard spin-column workflows.
Column Elution Chemistry
Elution is typically performed using Tris-based buffer or nuclease-free water, with volumes ranging from approximately 50&ndash;200 &micro;L depending on kit design and sample type. Water elution may be preferred for EDTA-sensitive downstream applications.
Scaling Beyond a Single Column
For higher throughput workflows, 96-well plate formats using the same silica-membrane chemistry enable simultaneous processing of multiple samples per centrifuge run. Spin-column formats remain best suited for method development and low-to-moderate sample volumes.
&nbsp;
<h2>Specifications Context:</h2>
&nbsp;
The most important parameters for spin-column blood/tissue genomic DNA kits are sample-type compatibility and elution buffer composition, as these determine whether additional pretreatment is required and whether the eluate is directly compatible with downstream workflows. A typical 200 &micro;L whole blood input yields low-microgram quantities of genomic DNA in an elution volume of approximately 50&ndash;200 &micro;L.
&nbsp;
Use MBP's <a href="mbpinc.net/quickorder">Quick Order tool</a> for bulk pricing or <a href="mbpinc.net/contact-us">contact the specialist team</a> to confirm pretreatment requirements for challenging tissue types.

Spin-column

GD2311 Blood DNA Isolation Kit

Blood DNA Mini Kit

Purification of genomic DNA from less than 1 mL blood sample\n

Blood DNA Mini Kit , 4 Preps

Blood DNA Mini Kit , 50 Preps

Blood DNA Mini Kit , 250 Preps

<h2>What are Spin-Column DNA/RNA Co-Extraction Kits for Cells, Tissue, and Blood?</h2>
&nbsp;
Spin-column DNA/RNA co-extraction kits for cells, tissue, and blood simultaneously purify genomic DNA and total RNA in separate fractions from the same mammalian sample using a sequential two-column silica-membrane workflow in a standard microcentrifuge. The Zymo Quick-DNA/RNA Miniprep Plus Kit loads the sample lysate onto a Zymo-Spin IIICG column that physically captures gDNA while RNA passes through to a Zymo-Spin IIC column for binding, washing, and elution - completing both DNA and RNA purification in under 15 minutes for cell pellets and 45-75 minutes (including Proteinase K digestion) for solid tissue biopsies. Choose the spin-column format for DNA/RNA co-extraction from cells, tissue, and blood when processing 1-24 samples per run, when automation infrastructure is not available, or when the fastest possible DNA + RNA turnaround from a limited biopsy sample is required.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" aria-level="1">
Quick-DNA/RNA&trade; Miniprep Kit for rapid co-extraction of total DNA and RNA from blood and tissues utilizing advanced spin-column technology
</li>
<li dir="ltr" aria-level="1">
Quick-DNA/RNA&trade; Microprep Plus Kit to recover high-purity nucleic acids from extremely small or rare samples using a specialized micro-elution column
</li>
<li dir="ltr" aria-level="1">
Quick-DNA/RNA Miniprep Plus Kit to ensure high-yield genomic DNA and total RNA yields using an ultra-clean spin-column workflow
</li>
<li dir="ltr" aria-level="1">
Blood RNA Mini Kit for the specific extraction of intact viral and total host RNA from whole blood samples using robust silica-membrane columns
</li>
</ul>
&nbsp;
<h2>How to Choose a Spin-Column DNA/RNA Co-Extraction Kit for Cells, Tissue, and Blood</h2>
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Miniprep Plus vs. Microprep Plus Format
The Miniprep Plus kit handles standard inputs (up to 5x10^6 cells or 30 mg tissue) and elutes in 25-100 ul per fraction, appropriate for most downstream applications. The Microprep Plus kit is designed for very low inputs -- 500 cells to 5,000 cells or 0.5-5 mg tissue -- with minimum elution volumes of 6-10 ul per fraction for maximum concentration from limited material. Use Microprep Plus for needle biopsy cores, laser-capture microdissected cells, single-well organoid lysates, and sorted immune cell populations.
DNA/RNA Shield for Sample Lysis and Stabilization
DNA/RNA Shield in the Miniprep Plus and Microprep Plus kits performs dual duty: it lyses cells on contact while simultaneously stabilizing DNA and RNA at room temperature, enabling sample collection and processing to be decoupled by hours or days without cold-chain handling. For tissue biopsies collected in the operating room that cannot be processed immediately, submerging in DNA/RNA Shield preserves RNA integrity for up to 30 days at room temperature -- the practical alternative to snap-freezing in liquid nitrogen.
Tissue Digestion Strategy
Soft, high-cellularity tissues (liver, spleen, kidney cortex) lyse completely in DNA/RNA Shield + Proteinase K at 55 degrees C within 30 minutes. Fibrous tissues (skeletal muscle, heart, skin, lung) require 1-2 hours of Proteinase K digestion or mechanical homogenization (bead-beating, tissue grinder) before column loading. For very fibrous tissue that resists Proteinase K digestion, add bead-beating in a lysis tube (0.5 mm beads) with DNA/RNA Lysis Buffer before proceeding to column loading.
On-Column DNase I for the RNA Fraction
Always include on-column DNase I treatment for RNA-seq and for RT-qPCR assays without intron-spanning primers. Skip DNase I only for RT-qPCR with exon-spanning primer pairs that distinguish cDNA from gDNA amplicons. The IIICG column physically depletes the majority of gDNA but does not eliminate 100%; residual gDNA in the RNA fraction produces false-positive amplification in RT-qPCR assays without an intron-spanning design.
Elution Strategy for Downstream Applications
For RNA-seq: elute RNA in 50-100 ul, quantify by Qubit RNA HS Assay, and verify RIN &gt;= 7 on a Bioanalyzer before library preparation. For RT-qPCR: elute in 25-50 ul for higher RNA concentration. For gDNA applications requiring &gt;= 5 kb fragments (WGS, WES, long-read sequencing): elute DNA in 50-100 ul and quantify by Qubit dsDNA BR Assay; avoid vortexing gDNA eluates to preserve high-molecular-weight fragment integrity.
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<h2>Specifications Context</h2>
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The Zymo Quick-DNA/RNA Miniprep Plus Kit produces gDNA (A260/A280 &gt;= 1.8, high molecular weight &gt;= 20 kb) and total RNA, including small RNAs &gt;=17 nt (A260/A280 &gt;= 1.8, RIN &gt;= 7 from fresh tissue) in under 15 minutes from cell pellets, with both analytes ready for next-generation sequencing without further cleanup. The Quick-DNA/RNA Miniprep Plus Kit is among the most widely used spin-column co-extraction kits in academic molecular biology, gene therapy, pharmacology, and cancer multi-omics research; its use is cited in published studies at institutions including Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center for paired genomic and transcriptomic analyses. For needle biopsy or LCM inputs where the Miniprep Plus minimum input cannot be met, the Microprep Plus format recovers both analytes from the single-cell level without carrier RNA or pre-amplification requirements.
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For guidance on selecting the right spin-column co-extraction format for your input type or for pricing, <a href="https://mbpinc.net/contact-us">contact the expert team at MBP Inc. </a>

Blood RNA Mini Kit

The EZgeneTM Viral DNA/RNA kit provides an easy and reliable method for isolating total viral DNA/RNA from plasma, serum, whole blood, urine and cell culture supernatant. This procedure has been tested for isolating nucleic acids from Hepatitis A, Hepatitis C and HIV. The isolated DNA/RNA can be used for PCR, RT-PCR and other downstream applications.