Plate Sealer

Plate Sealer Accessories

<h2>What Are Plate Sealer Accessories?</h2>
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Plate sealer accessories include consumable sealing materials and instrument hardware used with heat plate sealers. Consumable sealing materials, such as sealing films and foil seals, are the most frequently replaced accessories, with one seal used per plate. Films and foils vary in optical properties, adhesion, temperature resistance, and pierceability, making it important to select the appropriate type for PCR, qPCR, sample storage, or automated liquid handling. Instrument hardware accessories, such as sealing frames, adapter inserts, and replacement components, are model-specific and designed to maintain proper sealer performance. Before ordering, confirm whether your application requires an optically clear film, a pierceable foil, or a cryogenic-rated foil.
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<h2>What You Will Find</h2>
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<ul>
<li>Optically clear qPCR sealing films with peelable, pierceable, and strong-bond options.</li>
<li>Peelable sealing films compatible with most microplate types for PCR and qPCR workflows.</li>
<li>Strong-bond sealing films for polypropylene (PP) plates requiring secure sample containment.</li>
<li>Foil plate seals with peelable or strong-bond options for PP plates.</li>
<li>Foil seals suitable for DMSO applications and cold storage from -200&deg;C to 110&deg;C.</li>
</ul>
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<h2>How to Choose Plate Sealer Accessories</h2>
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Seal material: film vs. foil
Polymer films are optically transparent and required for qPCR, fluorescence assays, and plate readers that detect through the seal. They are suitable for thermal cycling and short-term storage. Aluminum foil seals provide superior evaporation protection and are preferred for long-term storage, solvent resistance, and applications that do not require optical read-through.
Optical properties for qPCR
Use optically clear, low-autofluorescence sealing films for real-time qPCR to maximize fluorescence detection sensitivity. Confirm compatibility with your PCR instrument and fluorescence detection wavelengths.
Cryogenic performance
For storage at -80&deg;C or below, select sealing materials designed to maintain adhesion and barrier integrity through repeated freeze-thaw cycles. Cryogenic-rated foil seals provide the most reliable long-term performance.
Pierceable vs. non-pierceable seals
Pierceable foil seals allow robotic or manual pipette access without removing the seal, making them suitable for automated workflows. Non-pierceable seals provide the highest barrier protection for storage but must be removed before accessing samples.
Format adapters and sealing frames
Sealing frames and adapter inserts help align sealing materials and non-standard microplate formats during heat sealing. Verify compatibility with both your plate sealer model and microplate format before ordering.
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<h2>Specifications Context</h2>
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Film thickness influences evaporation protection, optical clarity, and piercing performance. Polymer films are typically 60 to 100 micrometers thick, while aluminum foils are generally 50 to 70 micrometers thick. Also confirm whether your plate sealer uses pre-cut sealing sheets or roll-format sealing material, as these formats are not interchangeable.
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To discuss product availability or get selection guidance,&nbsp;<a href="https://mbpinc.net/contact-us">contact the MBP team</a>.

Foil seals, peelable for PP plates, 100/pk

The MS1000-F1 by Accuris Instruments is a pack of 100 peelable foil seals for polypropylene (PP) microplates, applied using the Accuris SmartSeal semi-automated thermal sealer (MS1000). The peelable foil provides hermetic closure for sample storage and compound library plates where wells need to be manually peeled open—distinct from the pierceable MS1000-PCR3 variant. Order at mbpinc.net using catalog number MS1000-F1.

Manufacture

Foil seals, strong bonding for cold storage (-200 to 110°C) and DMSO, for PP plates, 100/pk

MS1000-F2 by Accuris Instruments is the Accuris SmartSeal aluminum foil plate seal for polypropylene (PP) microplates — rated from −200 °C to +110 °C and resistant to DMSO, making it suitable for ultra-low temperature storage, liquid nitrogen banking, and DMSO-based compound library plates.

Optically clear sealing film for qPCR, Peelable, for most plate types, 100/pk

The MS1000-PCR1 by Benchmark Scientific is an optically clear, peelable qPCR sealing film supplied as 125 × 78 mm sheets (100/pack). Compatible with PP, PC, and PE 96-well plates, it maintains fluorescence-grade optical clarity across –110°C to 200°C and allows post-run sample access via its peelable adhesive—designed for use with the Benchmark MS1000 SmartSeal sealer and most standard heat sealers.

Optically clear sealing film for qPCR, Pierceable, for most plate types, 100/pk

MS1000-PCR3 by Benchmark Scientific is an optically clear, pierceable qPCR sealing film (125 mm × 78 mm) rated from −200°C to +110°C, compatible with PP, PC, and PE microplates. Each pack contains 100 sheets. Designed for use with the Accuris SmartSeal sealer (MS1000) and most standard thermal plate sealers, it keeps plates sealed during thermal cycling while allowing robotic tip piercing between workflow steps.

Optically clear sealing film for qPCR, Strong Bond, for PP plates, 100/pk

SmartSeal MS1000-PCR2 by Benchmark Scientific: optically clear, strong bond (permanent) sealing film for qPCR PP plates, 125 × 78 mm sheets, 100/pk. Designed for the Accuris SmartSeal MS1000 sealer. Suitable for qPCR thermal cycling and long-term sample storage at –80°C.

<h2>What Are Plate Sealers?</h2>
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A plate sealer is a laboratory instrument that applies a uniform heat seal to the surface of a standard SBS-format microplate, protecting samples from evaporation, contamination, aerosol carryover, and sample loss during PCR, qPCR, ELISA, NGS library preparation, and long-term storage. Even small amounts of evaporation from low-volume PCR reactions can alter reagent concentrations and affect amplification consistency, while inadequate sealing during frozen storage can lead to sample degradation through sublimation and repeated freeze-thaw cycles.&nbsp;Bench-top semi-automated heat sealers use controlled temperature and pressure to bond compatible polymer films or aluminum foils securely to the plate rim, producing consistent, reproducible seals with minimal operator variability. Typical sealing temperatures range from 80 to 200 degrees C, with sealing completed in 2 to 3 seconds after the instrument reaches operating temperature. Choose a heat plate sealer when your workflow requires reliable sealing for PCR, qPCR, NGS library preparation, or secure short- and long-term microplate storage.
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<h2>What you will find:</h2>
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<ul>
<li>Semi-automated and automated plate sealers for sealing standard and deepwell microplates.</li>
<li><a href="https://mbpinc.net/equipments/microscopes-balances-and-analytical-equipment/microplate-instruments/plate-sealer/plate-sealer-accessories">Plate Sealer Accessories</a>, including optically clear qPCR sealing films and foil seals for a variety of microplate applications.</li>
<li>Optically clear qPCR sealing films with peelable, pierceable, and strong-bond options for different plate types.</li>
<li>Foil plate seals with peelable or strong-bond adhesives for polypropylene (PP) plates, including DMSO-compatible cold storage applications.</li>
</ul>
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<h2>How to Choose a Plate Sealer</h2>
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Heat sealer vs. adhesive sealer vs. manual film applicator
Heat sealers produce hermetic, consistent seals by bonding non-adhesive sealing film to the plate at programmed temperature and pressure; the seal is uniform plate to plate and user to user, and holds integrity through thermal cycling (-80 to +100 degrees C). They require a warm-up period (3 to 6 minutes) and a sealing film or foil matched to the instrument. Adhesive sealers use pressure-sensitive film that the operator applies by rolling or pressing across the plate; no instrument warm-up is required, but seal quality is technique-dependent and less reliable for PCR thermal cycling or cryogenic storage. Manual film applicators (rollers or squeegees) ensure even pressure application of adhesive films and are intermediate in cost and reliability.
Sealing temperature and film compatibility
Most heat sealers cover a sealing temperature range of 80 degrees C to 200 degrees C with 1-degree increment control. PCR aluminum foil seals typically seal optimally at 175 to 185 degrees C; optically clear polymer films for qPCR seal at 160 to 175 degrees C; cell culture gas-permeable membranes seal at lower temperatures (80 to 120 degrees C). Confirm that the sealer's temperature range covers all seal types used in the lab, and that the instrument stores named protocols per seal type to prevent user parameter errors.
Plate format compatibility
Confirm the sealer's plate guide accommodates the plate formats in routine use: standard 96-well at 14.4 mm height; low-profile 96-well PCR plates (13.8 mm); 384-well plates; and deep-well plates (2 mL per well, up to 44 mm tall). Some sealers require format-specific adapter inserts or different sealing frames for 384-well and deep-well plates. Confirm the maximum plate height the instrument accommodates (typically 44 to 48 mm) and whether height adjustment is automatic or manual.
Platen temperature uniformity
Temperature uniformity across the sealing platen (plus or minus 3 degrees C or better across the full plate footprint) is the critical performance specification for qPCR and PCR plate sealers. Non-uniform platen temperature produces weaker seals in cooler zones (typically the outer corners and edges of the plate) where evaporation during thermocycling is most likely and where Cq value variability is first observed. Request platen temperature mapping data from the manufacturer across the full plate area at the intended sealing temperature before specifying a sealer for critical qPCR applications.
Throughput and automation integration
Manual heat sealers process one plate per cycle (2 to 3 seconds active sealing time plus operator load/unload time: approximately 1 plate per minute). Semi-automated sealers with motorized drawer eject the plate after sealing and include a stackable design for faster processing. Fully automated sealers integrate with liquid handling robots and process plates at 1 to 3 plates per minute without operator intervention. For drug discovery and NGS workflows processing 50 to 500 plates per day, specify a fully automated sealer with RS-232 or USB control interface.
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<h2>Specifications Context</h2>
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After sealing, allow the sealed plate to cool on a flat surface for 10 to 15 seconds before placing it in the thermocycler or centrifuge; premature handling before the seal cools and bonds to the rim can cause edge lifting, particularly in the outer rows. If the seal lifts at any position, the sealing temperature is too low, the plate rim was wet or contaminated before sealing, or the sealing film is incompatible with the specific plate brand. Foil seal materials for cryogenic storage must specify a minimum rated temperature of -80 degrees C or below; standard PCR foil seals may not maintain seal integrity below -40 degrees C during prolonged cold storage.&nbsp;
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To discuss product availability or get selection guidance,&nbsp;<a href="https://mbpinc.net/contact-us">contact the MBP team</a>.

User Manual

Brochure

SmartSeal Semi-Automated Microplate Sealer, 115V

SmartSeal Semi-Automated Microplate Sealer, 230V

Optically clear sealing film for qPCR, PEELABLE for most plate types, PP, PC, PE, etc., 100/pk

Optically clear sealing film for qPCR, STRONG BOND for PP plates, 100/pk

Optically clear sealing film for qPCR, PIERCEABLE for most plate types, PP, PC, PE, etc., 100/pk

SmartSeal Semi-Automated PlateSealer

SmartSeal™ Semi-Automated PlateSealer

The MS1000 SmartSeal™ Semi-Automated Microplate Sealer by Benchmark Scientific seals PCR plates, assay plates, and deep-well storage plates (up to 48 mm) with a programmable temperature range of 80°C to 200°C (±1°C accuracy) and sealing times from 0.5 to 10 seconds. Compatible with foil, pierceable, and transparent polymer seals on polypropylene, polystyrene, and polyethylene plates. Operates at 115V, 300W; dimensions 17.8 × 37 × 33 cm. Includes aluminum block adapter for PCR and assay plates.