

Z-VAD-FMK (Highly Pure) by Molecular Depot is a Z-VAD-FMK, a cell-permeable irreversible pan-caspase inhibitor. The fluoromethylketone group alkylates the active site cysteine of a caspase, so inhibition is covalent, and the Z-VAD sequence is accepted by caspases broadly rather than by one of them. It is used to block apoptosis in cells, as a pan-caspase inhibitor control in cell death research and in studies of caspase-independent death pathways. Each unit contains 2 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.