

Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride by Molecular Depot is a abbreviated Z-FR-AMC, a fluorogenic peptide substrate. Cleavage releases 7-amino-4-methylcoumarin, which fluoresces strongly where the intact conjugate does not, so activity is read continuously. It is used to measure cathepsin L, cathepsin B and related cysteine protease activity in enzyme assays and inhibitor screening. Each unit contains 5 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.