
Truncated Tau (AA297-391) (dGAE C322A) Protein Pre-formed Fibrils (B2022527) from Molecular Depot is pre-formed fibrils of the tau dGAE fragment (residues 297′,91) carrying the C322A substitution. Pre-formed fibrils are used as seeds to induce templated aggregation of endogenous protein in cultured neurons and other cells, and by stereotaxic injection in animal models of protein misfolding disease, as well as in biophysical aggregation and binding studies. Available from MBP, a registered vendor at leading US research institutions.