Name: SIEVA-3 Filtration Centrifuge
SKU: Z600-S3
Availability: InStock

Filtration Centrifuge

<h2>What Are Filtration Centrifuges?</h2>
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Filtration centrifuges, also called centrifugal filters, spin concentrators, or centrifugal ultrafiltration devices, are two-part filter units placed inside a standard benchtop centrifuge or microcentrifuge. They consist of an upper reservoir containing an ultrafiltration membrane and a lower filtrate collection tube. During centrifugation, solvent, salts, and small molecules pass through the membrane while proteins, antibodies, nucleic acids, and other larger biomolecules are retained and concentrated in the upper chamber. These devices support concentration factors of 25- to 80-fold or more in a single spin and are available with molecular weight cut-off (MWCO) options ranging from 2 kDa to 300 kDa. Common membrane materials include regenerated cellulose (RC) for low protein binding and broad chemical compatibility, and polyethersulfone (PES) for faster filtration rates.
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<h2>What You Will Find:</h2>
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<li><a href="https://mbpinc.net/equipments/centrifuges/filtration-centrifuge/accessories">Filtration Centrifuge Accessories:</a> Include filter materials with different pore sizes and perforated and non-perforated baskets. These tools allow efficient and controlled separation of particles.</li>
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<h2>How to Choose a Filtration Centrifuge Device</h2>
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MWCO Selection
The molecular weight cut-off determines which molecules are retained during centrifugation. A general guideline is to select an MWCO that is three to six times lower than the molecular weight of the target molecule. This approach helps maximize retention while maintaining efficient filtration performance.
Sample Volume and Device Format
Choose a filtration device that matches or slightly exceeds your starting sample volume. Small-volume devices accommodate hundreds of microliters, while larger formats support up to 20 mL for preparative and bioprocessing applications.
Membrane Material
Regenerated cellulose membranes provide minimal non-specific protein binding and broad pH compatibility, making them suitable for sensitive protein samples. Polyethersulfone membranes offer faster flow rates and are often preferred for viscous solutions and higher-concentration preparations.
Centrifuge and Rotor Compatibility
Ensure that the selected device fits the available rotor format and operates within the recommended centrifugal force range. Small devices fit standard microcentrifuge rotors, while larger filtration units may require 15 mL or 50 mL conical tube rotors.
Reverse-Spin Recovery
Many centrifugal filtration systems include a reverse-spin recovery step that helps maximize sample retrieval from the membrane surface. This technique is particularly valuable when working with dilute samples or low-abundance biomolecules.
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<h2>Specifications Context</h2>
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Most centrifugal ultrafiltration devices operate within a range of 3,000&ndash;5,000 &times;g. Exceeding the recommended force limits may damage the membrane or reduce sample recovery. Processing times vary depending on sample volume, concentration requirements, and membrane characteristics.
Modern regenerated cellulose membranes provide excellent protein recovery with minimal adsorption, while newer PES-based systems offer improved flow rates for demanding laboratory applications. These technologies continue to support life science, biotechnology, and pharmaceutical workflows requiring reliable concentration and buffer-exchange performance.
Don't miss your chance to get the right filtration centrifuge for your lab. <a href="https://mbpinc.net/contact-us">Contact the expert team</a> at Molecular Biology Products Inc. and get yours today.

Product Literature

 Hermle Benchmark SIEVA III Filtration Centrifuge

SIEVA-3 Filtration Centrifuge

The Hermle SIEVA-3 Filtration Centrifuge Series by Hermle is the SIEVA-3 Filtration Centrifuge, reaching 10,000 rpm / 7,825 × g with a speed range of 200–10,000 rpm. Designed for cake filtration, OLEUM oil testing, and sample clarification, it features a maintenance-free induction drive, stainless steel construction, transparent lid, and 5-year warranty. Filtration baskets sold separately; available in 120V and 230V. Available models: Z600-S3, Z600-S3-E, Z600-S3-TC, Z600-S3-TC-E.