
HY500084 by Applied Biological Materials (ABM) is a mouse monoclonal antibody (clone IHC703, IgG1) targeting ATRX, validated for IHC at 1:50–1:200 and ELISA. Loss of ATRX nuclear expression is a hallmark of IDH-mutant astrocytoma and is required for WHO CNS tumor grading under the 2021 classification. MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center.