Name: DNA/RNA Shield SafeCollect Swab Collection Kit
SKU: R1160
Availability: InStock

<h2 dir="ltr">What is DNA/RNA Shield?</h2>
 DNA/RNA Shield is a nucleic acid stabilization reagent developed by Zymo Research that preserves DNA and RNA in biological samples at ambient temperature (15&ndash;25 &deg;C) without freezing or refrigeration. The aqueous reagent permeates cells on contact, inactivating nucleases and infectious agents&mdash;including viruses, bacteria, fungi, and parasites&mdash;while maintaining the genetic integrity and gene expression profiles of samples for up to 28 days at room temperature or multiple years at &minus;20 &deg;C. Sample types include cells, tissues, swabs, blood, saliva, urine, feces, plant material, insects, and environmental specimens. DNA/RNA Shield is the primary reagent for any workflow requiring ambient-temperature nucleic acid preservation from collection through extraction.
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<h2 dir="ltr">What you will find:</h2>
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DNA/RNA stabilization solution for biological sample preservation
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Ambient temperature sample preservation reagents
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1X and 2X concentration formats for different sample types
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Nucleic acid protection reagents for molecular workflows
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Pathogen-inactivating preservation solutions for safer handling
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Compatible solutions for PCR, qPCR, and sequencing workflows
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General-purpose nucleic acid preservation reagents for research use
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<h2 dir="ltr"> How to Choose the Right DNA/RNA Shield Format</h2>
 1&times; Solution vs. 2&times; Concentrate The 1&times; ready-to-use solution (catalog R1100) is used directly: add 1 volume of reagent per 1 volume of liquid sample, or submerge tissue fully. The 2&times; concentrate (R1200) is used to treat high-volume liquid samples (blood, urine) where diluting the sample would reduce nucleic acid input. Prepare a working 1&times; solution by mixing 2&times; concentrate 1:1 with the liquid sample at collection.
Pre-filled Devices vs. Bulk Reagent Pre-filled collection tubes, swab kits, lysis tubes, and saliva kits deliver accurate volumes at the point of collection without pipetting. Bulk reagent (50 mL&ndash;250 mL) is used in the laboratory for tissue immersion, custom plate-based workflows, or when preparing multiple collection devices at once.
DNA-Only vs. Dual DNA + RNA Preservation DNA/RNA Shield preserves both simultaneously. If only DNA is required (e.g., genotyping, RFLP), any stabilization reagent is adequate. When RNA is the target&mdash;particularly for transcriptomics, gene expression, or viral RNA detection&mdash;DNA/RNA Shield is preferred over RNAlater because it requires no removal before extraction and prevents freeze-thaw degradation.
Downstream Extraction Compatibility DNA/RNA Shield is directly compatible with Zymo Research Quick-DNA, Quick-RNA, ZymoBIOMICS, and Direct-zol kits without removal. Third-party kits (QIAGEN DNeasy, Thermo Fisher MagMAX) require pilot testing; residual shield reagent can cause inhibition in some column-based systems at high concentrations.
Volume Per Sample For swab samples: pre-filled 1 mL or 2 mL collection tubes. For tissue: 10&times; volume reagent per gram; a 50 mg biopsy needs ~500 &micro;L reagent in a 2 mL tube. For stool: 1 mL reagent per 50&ndash;100 mg sample. For whole blood: use the 2&times; concentrate at a 1:5 blood-to-reagent ratio for DNA/RNA blood collection tubes.
<h2 dir="ltr"> Specifications Context</h2>
 DNA/RNA Shield has received FDA 510(k) clearance (K202641) for SARS-CoV-2 RNA preservation and viral inactivation. The reagent is supplied as a clear aqueous solution, RNase-free, DNase-free, and PCR-inhibitor-free per lot certificate. At &minus;20 &deg;C storage, DNA stability extends to 2+ years with no measurable freeze-thaw degradation. A precipitate may form at temperatures below 15 &deg;C; resolving requires warming to &gt;37 &deg;C for 10 minutes; reagent function is unaffected. DNA/RNA Shield is among the most-cited sample stabilization reagents in published microbiome, environmental genomics, and infectious disease surveillance literature.
 MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center. Bulk volume and PO orders accepted. <a href="https://mbpinc.net/contact-us">Contact the MBP team&nbsp;</a>to request a quote.

DNA/RNA Shield

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DNA/RNA Shield SafeCollect Swab Collection Kit

The DNA/RNA Shield SafeCollect Swab Collection Kit by Zymo Research provides a flocked swab and pierceable-safety-seal tube with DNA/RNA Shield for immediate pathogen inactivation and nucleic acid stabilization at point of collection. RNA stable over 1 month and DNA over 2 years at 4–30°C; no cold chain required. Available in 1 ml fill (R1160 series) and 2 ml fill (R1161 series), each as single, DX, 10-pack, and 50-pack formats: R1160, R1160-E, R1160-10, R1160-50, R1161, R1161-E, R1161-10, R1161-50.