Name: DNA/RNA Shield Collection Tube w/ Swab
SKU: R1106
Availability: InStock

<h2 dir="ltr">What is DNA/RNA Shield?</h2>
 DNA/RNA Shield is a nucleic acid stabilization reagent developed by Zymo Research that preserves DNA and RNA in biological samples at ambient temperature (15&ndash;25 &deg;C) without freezing or refrigeration. The aqueous reagent permeates cells on contact, inactivating nucleases and infectious agents&mdash;including viruses, bacteria, fungi, and parasites&mdash;while maintaining the genetic integrity and gene expression profiles of samples for up to 28 days at room temperature or multiple years at &minus;20 &deg;C. Sample types include cells, tissues, swabs, blood, saliva, urine, feces, plant material, insects, and environmental specimens. DNA/RNA Shield is the primary reagent for any workflow requiring ambient-temperature nucleic acid preservation from collection through extraction.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" aria-level="1">
DNA/RNA stabilization solution for biological sample preservation
</li>
<li dir="ltr" aria-level="1">
Ambient temperature sample preservation reagents
</li>
<li dir="ltr" aria-level="1">
1X and 2X concentration formats for different sample types
</li>
<li dir="ltr" aria-level="1">
Nucleic acid protection reagents for molecular workflows
</li>
<li dir="ltr" aria-level="1">
Pathogen-inactivating preservation solutions for safer handling
</li>
<li dir="ltr" aria-level="1">
Compatible solutions for PCR, qPCR, and sequencing workflows
</li>
<li dir="ltr" aria-level="1">
General-purpose nucleic acid preservation reagents for research use
</li>
</ul>
<h2 dir="ltr"> How to Choose the Right DNA/RNA Shield Format</h2>
 1&times; Solution vs. 2&times; Concentrate The 1&times; ready-to-use solution (catalog R1100) is used directly: add 1 volume of reagent per 1 volume of liquid sample, or submerge tissue fully. The 2&times; concentrate (R1200) is used to treat high-volume liquid samples (blood, urine) where diluting the sample would reduce nucleic acid input. Prepare a working 1&times; solution by mixing 2&times; concentrate 1:1 with the liquid sample at collection.
Pre-filled Devices vs. Bulk Reagent Pre-filled collection tubes, swab kits, lysis tubes, and saliva kits deliver accurate volumes at the point of collection without pipetting. Bulk reagent (50 mL&ndash;250 mL) is used in the laboratory for tissue immersion, custom plate-based workflows, or when preparing multiple collection devices at once.
DNA-Only vs. Dual DNA + RNA Preservation DNA/RNA Shield preserves both simultaneously. If only DNA is required (e.g., genotyping, RFLP), any stabilization reagent is adequate. When RNA is the target&mdash;particularly for transcriptomics, gene expression, or viral RNA detection&mdash;DNA/RNA Shield is preferred over RNAlater because it requires no removal before extraction and prevents freeze-thaw degradation.
Downstream Extraction Compatibility DNA/RNA Shield is directly compatible with Zymo Research Quick-DNA, Quick-RNA, ZymoBIOMICS, and Direct-zol kits without removal. Third-party kits (QIAGEN DNeasy, Thermo Fisher MagMAX) require pilot testing; residual shield reagent can cause inhibition in some column-based systems at high concentrations.
Volume Per Sample For swab samples: pre-filled 1 mL or 2 mL collection tubes. For tissue: 10&times; volume reagent per gram; a 50 mg biopsy needs ~500 &micro;L reagent in a 2 mL tube. For stool: 1 mL reagent per 50&ndash;100 mg sample. For whole blood: use the 2&times; concentrate at a 1:5 blood-to-reagent ratio for DNA/RNA blood collection tubes.
<h2 dir="ltr"> Specifications Context</h2>
 DNA/RNA Shield has received FDA 510(k) clearance (K202641) for SARS-CoV-2 RNA preservation and viral inactivation. The reagent is supplied as a clear aqueous solution, RNase-free, DNase-free, and PCR-inhibitor-free per lot certificate. At &minus;20 &deg;C storage, DNA stability extends to 2+ years with no measurable freeze-thaw degradation. A precipitate may form at temperatures below 15 &deg;C; resolving requires warming to &gt;37 &deg;C for 10 minutes; reagent function is unaffected. DNA/RNA Shield is among the most-cited sample stabilization reagents in published microbiome, environmental genomics, and infectious disease surveillance literature.
 MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center. Bulk volume and PO orders accepted. <a href="https://mbpinc.net/contact-us">Contact the MBP team&nbsp;</a>to request a quote.

DNA/RNA Shield

<h2 dir="ltr">What are UTM Tubes?</h2>
 Universal Transport Medium (UTM) tubes are pre-filled collection and transport systems containing Hanks' Balanced Salt Solution (HBSS) enriched with proteins, a pH indicator, and antibiotics that maintain the viability of viruses, Chlamydia, Mycoplasma, and Ureaplasma for 48 hours at room or refrigerated temperature. They are used in molecular diagnostics, viral culture, antigen detection, and NAAT-based workflows for respiratory, genital, and other clinical specimens. The Copan UTM&reg; (catalog 360C and related) is FDA-cleared and is cited in CDC guidelines as an acceptable transport system for SARS-CoV-2 specimens. Choose UTM tubes over plain saline when the specimen requires extended ambient-temperature stability, viral viability for culture, or compatibility with automated molecular diagnostic platforms validated for UTM matrix.
&nbsp;
<h2 dir="ltr">What you will find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Pre-filled UTM tubes for viral and microbial specimen transport</li>
<li dir="ltr" role="presentation">Swab-integrated collection systems for respiratory sampling</li>
<li dir="ltr" role="presentation">3 mL and 5 mL Universal Transport Medium tube formats</li>
<li dir="ltr" role="presentation">Sterile screw-cap tubes for secure clinical handling</li>
<li dir="ltr" role="presentation">Buffered transport medium for pathogen stabilization</li>
<li dir="ltr" role="presentation">Nasopharyngeal and/or oropharyngeal compatible sampling systems</li>
</ul>
<h2 dir="ltr"> How to Choose UTM Tubes</h2>
 Standard Tube vs. Round-Bottom (UTM-RT) Standard UTM tubes (12 &times; 80 mm, red cap, 3 mL) require swab removal and possible aliquoting before loading onto automated analyzers. The UTM-RT&reg; Round Bottom Tube is engineered for direct loading onto Roche cobas&reg; 5800/6800/8800 platforms without aliquoting or swab removal, saving processing steps in high-volume clinical labs. Choose UTM-RT if your laboratory runs cobas instrumentation at scale.
With or Without Swab Bulk media tubes (tube-only format) suit labs that stock their own swab type. Kit configurations pair UTM tubes with Copan FLOQSwabs&reg; (flocked nylon), which provide 10&ndash;100&times; greater cell elution than rayon or Dacron swabs, directly impacting the sensitivity of downstream NAAT and antigen tests. For nasopharyngeal specimens, the minitip FLOQSwab + UTM combination is the standard validated pairing.
Volume: 1 mL vs. 3 mL Fill A 1 mL fill is used when a higher specimen concentration is needed for sensitive assays or limited-volume extraction protocols. A 3 mL fill is the standard for most NAAT platforms. Using a 1 mL tube on a platform calibrated for 3 mL inputs may cause out-of-range results; always confirm volume requirements with your assay's instructions for use.
Bead Inclusion UTM tubes with 3 glass beads facilitate the release and dispersion of patient material from the swab tip during vortexing, improving homogeneity before aliquoting. For platforms that recommend homogenization (e.g., high-mucosity respiratory specimens), bead-containing UTM is preferred.
Regulatory Status For clinical diagnostic use, confirm that your specific UTM tube carries FDA 510(k) clearance. Copan UTM&reg; (K910043 and subsequent clearances) is FDA-cleared for collection, transport, preservation, and long-term freeze storage of clinical specimens and complies with CLSI M40-A2 standards. Verify product-specific regulatory status before deploying in clinical settings.
&nbsp;
<h2 dir="ltr">Specifications Context</h2>
 UTM contains HBSS supplemented with bovine serum albumin (BSA), sucrose, gentamicin, amphotericin B, and a phenol-red pH indicator. The antibiotic-antimycotic formulation inhibits bacterial and fungal overgrowth without affecting viral, Chlamydial, or Mycoplasmal viability. At ambient temperature (15&ndash;25 &deg;C) or 2&ndash;8 &deg;C, UTM maintains organism viability for 48 hours. For long-term storage of viral isolates, specimens can be frozen at &minus;70 &deg;C or colder; storage at &minus;20 &deg;C is specifically discouraged by Copan because it can result in loss of viral infectivity. UTM-RT has received CE-IVDR compliance marking. As of 2026, Copan UTM&reg; is carried by MBP and is a registered catalog item for institutional procurement customers.
 MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, and MD Anderson Cancer Center. Direct PO ordering and bulk pricing available.&nbsp;<a href="https://mbpinc.net/contact-us">Contact MBP</a> &mdash;they&rsquo;ll help you sort out the right UTM setup without second-guessing.

UTM Tubes

<h2 dir="ltr">What are VTM tubes?</h2>
 VTM tubes are pre-filled, screw-cap polypropylene tubes containing viral transport medium &mdash; an isotonic buffer designed to preserve virus viability and viral RNA between specimen collection and PCR or culture in the lab. The CDC reference formulation (SOP DSR-052) is Hank's Balanced Salt Solution with 2 % heat-inactivated fetal bovine serum, 100 &micro;g/mL gentamicin, and 0.5 &micro;g/mL amphotericin B &mdash; antibiotics that suppress contaminating bacteria and fungi without inactivating the target virus. Most are sold as 3 mL aliquots in a 10 mL or 15 mL conical tube. Buy from this category whenever a respiratory or other virus specimen must travel from the point of collection to a testing laboratory.
&nbsp;
<h2 dir="ltr">What You Will Find:</h2>
&nbsp;
<ul>
<li dir="ltr" role="presentation">Viral Transport Medium (VTM) Tubes &ndash; Medical-grade vials designed to maintain viral viability during transit.</li>
<li dir="ltr" role="presentation">Universal Transport Medium (UTM) &ndash; Versatile, bead-free systems for preserving viruses, chlamydia, and mycoplasma.</li>
<li dir="ltr" role="presentation">DNA/RNA Shield Collection Tubes &ndash; Advanced tubes that lock in nucleic acid profiles and inactivate pathogens.</li>
<li dir="ltr" role="presentation">Smart Collection &amp; Transport Systems &ndash; High-performance vials and kits for streamlined diagnostic management.</li>
<li dir="ltr" role="presentation">Saliva Collection Kits &ndash; User-friendly funnel and vial systems for non-invasive, high-yield sampling.</li>
<li dir="ltr" role="presentation">Flocked Swab &amp; Medium Combos &ndash; Precision-engineered pairings for maximum recovery and immediate stabilization.</li>
</ul>
<h2 dir="ltr"> How to choose VTM tubes</h2>
&nbsp;
Verify the formulation against CDC SOP Confirm the medium follows CDC SOP DSR-052 (HBSS + 2 % HI-FBS + gentamicin + amphotericin B); some lots substitute 1 % bovine serum albumin or fluconazole &mdash; both are accepted variants, but the substitution should be on the certificate of analysis.
Check tube material and IATA compliance For specimen shipping, the primary tube should be polypropylene, screw-capped, and rated to 95 kPa internal pressure per IATA packaging instruction 650. MedSchenker tubes are 100 % polypropylene and 95 kPa compliant.
Match volume to the swab and assay 3 mL of medium in a 10 mL tube is the CDC reference fill for nasopharyngeal swabs; 1 mL or 1.5 mL versions exist for pediatric and difficult-to-collect specimens where dilution must be minimized.
Confirm storage and stability Standard VTM stabilizes respiratory viruses for about 72 hours at 2&ndash;8 &deg;C; some commercial formulations are room-temperature stable for up to six months. The MedSchenker Smart Transport Medium variant maintains organism viability for 96 hours at room temperature. 
&nbsp;
<h2 dir="ltr">Specifications context</h2>
 A VTM tube is defined by its formulation, fill volume, primary container material, screw-cap design, and validated stability window. The MedSchenker line is manufactured by Vectormed (a Vectornate company, headquartered in Mahwah, New Jersey, and manufactured in South Korea), is FDA-cleared and CE-marked, and ships sterile in individual peel-pouch or bulk case packaging. As of 2026, MBP stocks 3.0 mL and 1.5 mL MedSchenker VTM formats and the Smart Transport Medium variant alongside paired flocked swabs.&nbsp; 
&nbsp;
Don&rsquo;t let your viral titers drop. Browse our VTM inventory and hit up the<a href="https://mbpinc.net/contact-us" style="color: #236fa1; text-decoration: underline;"> MBP team </a>for a custom quote today.

VTM Tubes

MSDS

Quick Protocol

Instructions For Use (Full) (CE)

Instructions For Use (Quick) (CE)

Recommended Purification

DNA/RNA Shield Collection Tube w/ Swab

R1106 by Zymo Research is the DNA/RNA Shield&trade; Collection Tube with Swab, a 10-pack of sterile 12 &times; 80 mm polypropylene vials pre-filled with 1 mL of DNA/RNA Shield, each with a flocked nylon (Hydraflock) swab and an 80 mm molded breakpoint. DNA/RNA Shield inactivates pathogens at point of collection and stabilizes RNA for at least 28 days at ambient temperature (5&ndash;30&deg;C); DNA remains stable for at least 2 years under the same conditions. No cold chain is required for transport. Available in 1 mL or 2 mL fill, 10- or 50-packs, with CE-marked versions of the 50-packs (R1107-E, R1109-E).
Validated for buccal, nasal, throat, vaginal, rectal, and wound swabs, as well as environmental surfaces. Compatible with Zymo Quick-RNA Viral MagBead and KingFisher Flex for downstream automated extraction.
MBP is a registered vendor for Howard Hughes Medical Institute, Vanderbilt University, MD Anderson Cancer Center, Eurofins, and many other institutes across the USA. Order via <a href="https://www.mbpinc.net/quickorder">Quick Order</a> or contact <a href="mailto:customerservice@mbpinc.net">customerservice@mbpinc.net</a>.