
Y011290 by MBP is a rabbit polyclonal antibody detecting PKR (EIF2AK2) phosphorylated at Threonine 451 in the kinase activation loop — an autophosphorylation mark of dsRNA-activated, dimerised PKR. Apparent MW ~65 kDa. Validated for WB, IHC, and ELISA in human samples. Key marker for antiviral innate immunity and ISR kinase activation. Research Use Only.