Anti-Merlin (Phospho-Ser518)

Y011266 by MBP is a rabbit polyclonal antibody detecting Merlin (NF2) phosphorylated at Serine 518, a PAK1/PAK2-dependent modification that inactivates Merlin's tumour suppressor function by driving the open, inactive conformation. pSer518 is elevated at low cell density and reduced at high cell density/contact inhibition. MW ~69 kDa. WB, IHC; human. Research Use Only.