Anti-IRS-1 (Phospho-Ser636)

Y011230 by MBP is a rabbit polyclonal antibody detecting IRS-1 (IRS1) phosphorylated at Serine 636, a negative regulatory site phosphorylated by mTOR-S6K1, ERK, and JNK that inhibits IRS-1 function and contributes to insulin resistance. MW ~165–185 kDa (anomalous). Validated for WB, IHC, IF, and ELISA. Human, mouse, rat. Research Use Only.