Anti-HSP27 (Phospho-Ser78)

Y011247 by MBP is a rabbit polyclonal antibody detecting HSP27 (HSPB1) phosphorylated at Serine 78, one of three MK2 (MAPKAP Kinase 2) substrate sites downstream of p38 MAPK. pSer78 drives HSP27 oligomer dissociation and regulates actin cytoskeleton dynamics and anti-apoptotic activity under stress. MW ~27 kDa. Validated for WB, IHC, and IF. Human, mouse, rat. Research Use Only.