Anti-ß-Catenin (Phospho-Ser37)

Y011219 by MBP is a rabbit polyclonal antibody detecting β-Catenin (CTNNB1) phosphorylated at Serine 37, a sequential GSK-3β phosphorylation in the Wnt destruction complex that creates a β-TrCP docking site for ubiquitin-mediated degradation. Signal is absent in Wnt-activated or APC/CTNNB1-mutant cells. MW ~92 kDa. Validated for WB, IHC, ELISA. Human, mouse, rat. Research Use Only.