The Z446-500-A225C by Hermle Labortechnik GmbH is a 2-pack of 175/225 ml conical bottle inserts for the Z446-04500 4 × 500 ml fixed-angle rotor, compatible with Hermle Z446 and Z496 centrifuges. The inserts convert 500 ml rotor positions to accept intermediate-volume conical bottles, supporting preparative centrifugation at up to 10,000 × g.