

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium Tetrafluoroborate by Molecular Depot is a O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, known as TBTU, a uronium coupling reagent for solid-phase peptide synthesis. A uronium coupling reagent converts the carboxylic acid of the incoming amino acid into a benzotriazole ester in situ, which then acylates the amine on the resin quickly and with little racemisation. It is used as the coupling reagent in Fmoc solid-phase peptide synthesis, in amide bond formation and in peptide library preparation. Each unit contains 1 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.