

N-Hydroxyphthalimide (Highly Pure) by Molecular Depot is a N-hydroxyphthalimide, used to prepare amine nucleosides for coupling into non-anionic antisense oligonucleosides. The hydroxylamine nitrogen of N-hydroxyphthalimide is the basis of two quite different uses: it introduces a protected aminooxy group in synthesis, and it generates a nitrogen-centred radical that abstracts hydrogen, which makes it an aerobic oxidation catalyst. It is used to introduce aminooxy groups in nucleoside and oligonucleotide chemistry, as an organocatalyst in aerobic oxidation and in organic synthesis. Each unit contains 1 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.