

DAPT (Highly Pure) by Molecular Depot is a highly pure DAPT, a small molecule inhibitor of gamma-secretase. Gamma-secretase cuts the Notch receptor to release its intracellular domain, and it is also the enzyme that makes the amyloid beta peptides from the amyloid precursor protein, so inhibiting it blocks both processes. It is used to block Notch signalling in cell and organoid culture, in stem cell differentiation protocols and in amyloid processing and gamma-secretase research. Each unit contains 5 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.