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Pipette Controllers for Serological Pipette Operation

 

Pipette controllers are battery-powered or mains-powered motorised instruments that hold and actuate glass or plastic serological pipettes (1–100 mL) for accurate, ergonomic medium-volume liquid transfer without manual mouth-pipetting or rubber bulbs. Variable-speed aspirate and dispense control, a hydrophobic inline filter protecting the motor, and a universal cone accepting all standard serological pipette diameters are the core features. 

MBP Inc. supplies pipette controllers for cell culture and research labs across the USA and Canada, with Quick Order and PO purchasing. Request a quote today by contacting  customerservice@mbpinc.net

Pipette Controller

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What Are Pipette Controllers?


A pipette controller (also called a pipetting aid, motorised pipette filler, or pipette boy) is a battery-operated instrument that accepts and drives 1–100 mL glass or plastic serological pipettes, replacing the rubber bulb, Pi-pump, and manual mouth-pipetting techniques. A motorised rotating wheel or roller generates controlled airflow to aspirate and dispense liquid at variable speeds; a hydrophobic 0.2 µm inline filter prevents liquid and aerosol from reaching the motor. Controllers accept all standard serological pipette diameters (1 mL to 100 mL) through a silicone or rubber cone adapter. They are the standard dispensing tool for media preparation, cell culture reagent transfer, serial dilutions in large volumes, and reagent bottle-to-flask transfers. The disposable consumables used in the instrument. A pipette controller is required for safe, ergonomic use of serological pipettes in any volume from 1 mL to 100 mL — the rubber bulb is not a recommended alternative.

 

What you will find:

 

  • Electronic pipette controllers for precise liquid control

  • Manual pipette controllers for routine laboratory use

  • Lightweight ergonomic pipette controllers

  • Adjustable speed pipette controllers for controlled dispensing

  • Controllers compatible with glass and plastic serological pipettes

  • Sterile-use pipette controllers for sensitive applications

  • High-precision aspirating controllers for accurate volume handling


How to Choose a Pipette Controller


Power Source: Battery vs Rechargeable vs Mains
Battery-powered controllers (AA or rechargeable internal battery) provide cordless flexibility across the bench and BSC. Rechargeable lithium-ion controllers offer 8–10 hours of continuous use per charge and charge from a base stand. Mains-powered controllers provide continuous operation without charge interruption — preferred in high-throughput cell culture facilities.

Speed Control
Two-speed controllers offer slow (for precise fill) and fast (for rapid dispense) modes. Variable-speed controllers with a continuous-pressure or stepless trigger allow fine-tuned flow rate adjustment for viscous media, delicate cell suspensions, or filling against gravity into narrow-neck vessels.

Filter: Inline 0.2 µm Hydrophobic Filter
A 0.2 µm hydrophobic inline filter is the critical protection component — it prevents liquid from entering the motor during accidental over-aspiration. Filters should be replaced when liquid reaches the filter or when flow resistance increases noticeably; replacement filters are sold separately for most models.

Universal Cone Compatibility
Confirm the controller's cone adapter accepts your pipette brand's tip diameter. Most controllers use a silicone or rubber cone that accommodates 1–100 mL serological pipettes from Falcon, Globe Scientific, and Nest Scientific without adapters.

Autoclavability
Controllers intended for BSC and sterile cell culture use should have an autoclavable cone, nose piece, and filter assembly. They have autoclavable lower sections; the battery/electronic module is not autoclavable.


Specifications Context


Standard pipette controllers accept serological pipette diameters from 1 mL (narrow shaft) through 50 mL and 100 mL (wide-body). Replacement 0.2 µm hydrophobic filters are sold in packs; filter replacement interval is typically every 6–12 months or immediately after liquid ingress. It has a runtime of approximately 8 hours per charge on a single lithium-ion battery. 

 

Control your workflow with ease—designed for smooth aspiration, consistent dispensing, and dependable performance at every step. Contact the MBP Team now.

FAQ

A pipette controller is a battery-powered motorised instrument that holds and drives 1–100 mL serological pipettes, replacing the rubber bulb and eliminating manual mouth-pipetting. It is used for media preparation, cell culture reagent transfer, serial dilutions in large volumes, and flask-to-flask liquid transfer where precise speed control and contamination safety are needed.
Most pipette controllers accept all standard serological pipette diameters from 1 mL through 100 mL via a silicone or rubber cone adapter — including brands such as Falcon, Globe Scientific, and Nest Scientific. Confirm the specific cone adapter diameter range for the controller model before ordering if using non-standard pipette brands.
The Eppendorf Easypet 3 provides approximately 8 hours of continuous operation per lithium-ion charge. Integra PIPETBOY has a similar runtime. Controllers charge from a dedicated base stand or USB adapter; most reach full charge in 2–4 hours depending on the model.
The 0.2 µm hydrophobic inline filter is the primary protection between the liquid aspirated in the serological pipette and the controller's motor. It blocks liquid and aerosol from reaching the motor in the event of over-aspiration. When liquid reaches the filter, the filter must be replaced immediately to prevent motor damage and contamination carryover.
The cone adapter, nose piece, and filter assembly of most research-grade pipette controllers (Eppendorf Easypet 3, Integra PIPETBOY) are autoclavable at 121°C for sterile cell culture and BSC use. The electronic module and battery are not autoclavable. Always confirm which components are rated for autoclave sterilisation before processing the controller.
A pipette controller is designed for 1–100 mL serological glass or plastic pipettes used in bulk liquid transfers — media, buffers, and reagents in the millilitre range. A micropipettor (e.g., Eppendorf Research Plus) handles 0.1–5,000 µL using disposable polypropylene tips. The two instruments are complementary: controllers for large-volume serological work, micropipettors for precise small-volume transfers.
Rechargeable cordless pipette controllers (Eppendorf Easypet 3, Integra PIPETBOY) are designed for use inside biosafety cabinets (BSCs) — their cordless operation and autoclavable lower section make them compatible with sterile work environments. The controller should be surface-decontaminated before entering the BSC per your facility's SOPs.
Variable-speed control allows the flow rate to be continuously adjusted during aspiration and dispensing. For viscous media such as Matrigel or methylcellulose, slow speed prevents foaming and over-aspiration. For rapid large-volume transfers, high speed reduces cycle time. Two-speed controllers (slow/fast) are sufficient for routine cell culture; stepless variable speed is preferred for delicate or high-viscosity applications.
The 0.2 µm hydrophobic inline filter should be replaced every 6–12 months under routine use, or immediately if liquid reaches the filter — visible as discolouration or increased flow resistance. Replacement filters for Eppendorf Easypet 3 and Integra PIPETBOY are sold separately in packs; always keep spare filters on hand in high-throughput cell culture labs.
MBP Inc. accepts purchase orders for pipette controllers and offers a Quick Order tool for recurring lab instruments. MBP is a registered vendor at Howard Hughes Medical Institute, MD Anderson Cancer Center, and Vanderbilt University, supporting institutional PO processing for procurement teams across the USA and Canada.
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