

Citrullinated Core Histones (bovine) by Molecular Depot is a preparation of bovine core histones that have been citrullinated, a modification in which peptidylarginine deiminases convert arginine to citrulline. Citrullination changes protein structure and interactions and so affects chromatin structure and gene expression. It is used as a substrate and antigen in citrullination research, in anti-citrullinated histone antibody assays and in studies of neutrophil extracellular traps. Each unit contains 100 µg. MBP supplies Molecular Depot protein reagents to research labs in the United States, Canada and worldwide.