

Caspase-1 Substrate VI Fluorogenic by Molecular Depot is a Z-YVAD-AFC, a fluorogenic substrate for caspase-1. Cleavage releases 7-amino-4-trifluoromethylcoumarin, which fluoresces further to the red than the more common aminomethylcoumarin, so it suffers less interference from sample autofluorescence. It is used to measure caspase-1 activity in inflammasome research and in caspase inhibitor screening. Each unit contains 2 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.