

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate by Molecular Depot is a (benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, known as PyBOP, a phosphonium coupling reagent. A phosphonium coupling reagent activates a carboxylic acid as a benzotriazole ester without the risk of capping the growing peptide, which is the side reaction the uronium reagents can cause when they are used in excess. It is used as the coupling reagent in Fmoc solid-phase peptide synthesis, in difficult couplings and macrocyclisations and in amide bond formation. Each unit contains 250 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.