6-Azauracil (Highly Pure)

6-Azauracil (Highly Pure) by Molecular Depot is a 6-azauracil, a uracil analogue and a potent inhibitor of orotidine-5′-phosphate decarboxylase in pyrimidine nucleotide biosynthesis. The compound is converted in the cell to 6-azauridine monophosphate, which is the actual inhibitor, so the effect depends on the cell possessing the salvage enzymes that make that conversion. It is used to deplete nucleotide pools and to induce transcriptional stress in yeast and cell culture, in pyrimidine metabolism research and in transcription elongation studies. Each unit contains 10 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.