

5-Fluoroorotic Acid Monohydrate (5-FOA) by Molecular Depot is a 5-fluoroorotic acid monohydrate, known as 5-FOA, the selection agent of yeast molecular genetics. Yeast carrying a functional URA3 gene converts 5-fluoroorotic acid into a toxic nucleotide, so the compound kills URA3-positive cells and spares those that have lost the gene. It is used to select against the URA3 marker in yeast, in gene disruption and marker recycling and in yeast genetics research. Each unit contains 1 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.