

2-Iminobiotin (Highly Pure) by Molecular Depot is a 2-iminobiotin, the cyclic guanidino analogue of biotin. Replacing the biotin ureido ring with a guanidino group makes binding to avidin pH-dependent, so the analogue binds tightly at alkaline pH and releases at around pH 4. It is used for reversible avidin and streptavidin affinity capture, as a selective nitric oxide synthase inhibitor and in biotin-binding protein research. Each unit contains 10 mg. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.