

2-Deoxy-D-glucose by Molecular Depot is a 2-deoxy-D-glucose, a glucose analogue that cells take up but cannot metabolise, which disrupts glycolysis at the hexokinase step. Hexokinase phosphorylates 2-deoxyglucose as readily as glucose, but the product cannot be isomerised onward, so it accumulates and blocks the pathway from inside. It is used to inhibit glycolysis in cell culture, in glucose uptake and transport assays and in cancer metabolism and autophagy research. Each unit contains 5 mg. MBP supplies Molecular Depot carbohydrate reagents to research labs in the United States, Canada and worldwide.