

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate by Molecular Depot is a 1H-benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate, known as BOP or the Castro reagent, a phosphonium coupling reagent for peptide synthesis. The reagent activates a carboxylic acid as a benzotriazolyl ester that an amine then attacks, which forms the amide bond with little racemisation. It is used to form amide bonds in solid phase and solution peptide synthesis, in hindered couplings and in fragment condensation. Each unit contains 1 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.