

1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate by Molecular Depot is a 1H-benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate, known as PyBOP, a phosphonium coupling reagent for peptide synthesis. Phosphonium coupling reagents activate a carboxylic acid as a benzotriazolyl ester, which an amine then attacks, and unlike the uronium reagents they cannot cap a free amine. It is used to form amide bonds in solid phase and solution peptide synthesis, in difficult and hindered couplings and in fragment condensation. Each unit contains 1 g. MBP supplies Molecular Depot research reagents to research labs in the United States, Canada and worldwide.